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Most U.S. hospitals did not adopt effective interventions to address crowding in emergency departments

The most crowded emergency departments in the U.S. have not adopted proven interventions to address crowding, a major public health concern.

8 Dec 2015

Coordinated health care not helping people with mental health conditions

People who are diagnosed with mental health conditions did not see improvements in coordination and quality of care as hoped but did not experience large cuts in access as some had feared under an early alternative payment model designed to encourage coordinated health care, according to a team led by researchers from Harvard Medical School and Johns Hopkins Bloomberg School of Public Health.

8 Dec 2015

Androgen deprivation therapy for prostate cancer may up Alzheimer's disease risk

Men taking androgen deprivation therapy (ADT) for prostate cancer were almost twice as likely to be diagnosed with Alzheimer's disease in the years that followed than those who didn't undergo the therapy, an analysis of medical records from two large hospital systems by Penn Medicine and Stanford University researchers has shown.

8 Dec 2015

Ibrutinib more effective than traditional chemotherapy in older untreated patients with CLL

A multi-center, international, randomized, Phase III study of older untreated patients with chronic lymphocytic leukemia (CLL) demonstrated that ibrutinib, a kinase inhibitor, is significantly more effective than traditional chemotherapy with chlorambucil.

7 Dec 2015

Prophylactic antibiotics reduce risk of serious bacterial infections in children with ALL

Prophylactic antibiotics significantly reduce the risk of serious bacterial infections in children during the critical first month of treatment for acute lymphoblastic leukemia (ALL), the most common childhood cancer, according to a U.S. and Canadian study led by investigators from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

7 Dec 2015

Gene therapy shows promise in children with Wiskott-Aldrich syndrome

Researchers reported promising preliminary outcomes for the first four children enrolled in a U.S. gene therapy trial for Wiskott-Aldrich syndrome (WAS), a life-threatening genetic blood and immune disorder, at the 57th annual meeting of the American Society of Hematology (abstract #260).

7 Dec 2015

Research highlights importance of controlling hospital and nursing home infection

A Rhode Island Hospital and The Miriam Hospital study found that a small percentage of nursing home patients carrying multi drug-resistant bacteria are admitted to hospitals without showing symptoms caused by the bacteria. The research, published in the American Journal of Infection Control, highlights the importance of hospital and nursing home infection control practices.

1 Dec 2015

Combination of antiviral medications can eradicate HCV infection in patients with advanced liver disease

A large multi-center clinical trial has found that a combination of antiviral medications can eradicate hepatitis C infection in more than 90 percent of patients with advanced liver disease. Known as the ASTRAL-4 trial, the study was co-led by investigators at Beth Israel Deaconess Medical Center and Intermountain Medical Center and published online Nov. 17 in The New England Journal of Medicine.

1 Dec 2015

Scientists can accurately measure microbial growth rates inside gastrointestinal tracts

For the first time, scientists can accurately measure population growth rates of the microbes that live inside mammalian gastrointestinal tracts, according to a new method reported in Nature Communications by a team at the Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard Medical School.

1 Dec 2015

DNA sequence variation can influence gene activity in developing human brain

An international research collaboration has shed new light on how DNA sequence variation can influence gene activity in the developing human brain.

1 Dec 2015

Air evacuations may pose significant added risk to patients with traumatic brain injury

Over the past 15 years, more than 330,000 U.S. soldiers have suffered a traumatic brain injury (TBI). It is one of the leading causes of death and disability connected to the country's recent conflicts in Afghanistan and Iraq. Many of these patients were evacuated by air from these countries to Europe and the U.S. for further treatment. In general, these patients were flown quickly to hospitals outside the battle zone, where more extensive treatment was available.

1 Dec 2015

Medical professionals compare different treatment methods for Neuromyelitis optica

In the course of a study conducted throughout Germany, medical professionals have compared different treatment methods for Neuromyelitis optica, an inflammatory disease of the central nervous system. It turned out that the best results were not achieved with conventional steroid therapy. Under the auspices of the Ruhr-Universität Bochum and the Hannover Medical School, the team published their findings in the journal Annals of Neurology.

30 Nov 2015

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

In addition to their well established cholesterol lowering benefits, statins also have potent anti-inflammatory, anti-fibrotic and antioxidant effects, which continue to be identified in a wide range of diseases.

30 Nov 2015

Medical Research Council announces prestigious doctoral training awards

The Medical Research Council has announced it will be funding 15 PhDs at the University of Warwick over the next three years.

26 Nov 2015

Medical professionals compare different treatment options for Neuromyelitis optica

26 Nov 2015

Researchers begin landmark clinical study to restore normal insulin secretion in people with type 1 diabetes

Investigators at Montreal's Lady Davis Institute at the Jewish General Hospital and McGill University Health Centre have announced the start of a landmark clinical study aimed at restoring normal insulin secretion in people with longstanding type 1 diabetes.

26 Nov 2015

Allergan, Rugen Therapeutics collaborate to discover and develop novel therapies for ASD and OCD

Allergan plc, a leading global pharmaceutical company, and Rugen Therapeutics, a start-up biotechnology company focused on the development of novel treatments for unmet CNS disorders and funded by the F-Prime Biomedical Research Initiative, today announced that they have entered into an exclusive collaboration to support the discovery and development of novel therapies for Autism Spectrum Disorders (ASD) and Obsessive Compulsive disorders (OCD).

25 Nov 2015

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

A group of people with fatal H1N1 flu died after their viral infections triggered a deadly hyperinflammatory disorder in susceptible individuals with gene mutations linked to the overactive immune response, according to a study in The Journal of Infectious Diseases.

25 Nov 2015

UNC study reveals how specific schizophrenia symptoms linked to distinct brain circuits

Schizophrenia, a severe mental disorder affecting about one in 100 people, is notoriously difficult to diagnose and treat, in large part because it manifests differently in different people. A new study published today in Molecular Neuropsychiatry helps explain why.

25 Nov 2015

Researchers offer novel solution to promote successful radiotherapy for cancer patients

Researchers at The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai have discovered a key mechanism by which radiation treatment (radiotherapy) fails to completely destroy tumors. And, in the journal Nature Immunology, they offer a novel solution to promote successful radiotherapy for the millions of cancer patients who are treated with it.

25 Nov 2015

Medical School News and Research

Most U.S. hospitals did not adopt effective interventions to address crowding in emergency departments

Coordinated health care not helping people with mental health conditions

Androgen deprivation therapy for prostate cancer may up Alzheimer's disease risk

Ibrutinib more effective than traditional chemotherapy in older untreated patients with CLL

Prophylactic antibiotics reduce risk of serious bacterial infections in children with ALL

Gene therapy shows promise in children with Wiskott-Aldrich syndrome

Research highlights importance of controlling hospital and nursing home infection

Combination of antiviral medications can eradicate HCV infection in patients with advanced liver disease

Scientists can accurately measure microbial growth rates inside gastrointestinal tracts

DNA sequence variation can influence gene activity in developing human brain

Air evacuations may pose significant added risk to patients with traumatic brain injury

Medical professionals compare different treatment methods for Neuromyelitis optica

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

Medical Research Council announces prestigious doctoral training awards

Medical professionals compare different treatment options for Neuromyelitis optica

Researchers begin landmark clinical study to restore normal insulin secretion in people with type 1 diabetes

Allergan, Rugen Therapeutics collaborate to discover and develop novel therapies for ASD and OCD

People with viral infections and identical gene mutations may be prone to hyperinflammatory disorder

UNC study reveals how specific schizophrenia symptoms linked to distinct brain circuits

Researchers offer novel solution to promote successful radiotherapy for cancer patients

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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