Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Sirolimus reduces risk of cancer in kidney transplant patients

A new study published in this month's issue of the Journal of the American Society of Nephrology shows that the risk of cancer in kidney transplant recipients was reduced by more than 50% at five years post transplantation in those patients who were treated with sirolimus following withdrawal of cyclosporine at three months.

13 Feb 2006

Cellular discovery suggests possibilities for drug therapy for kidney disease

Scientists at the University of California, Santa Barbara have reported a discovery at the cellular level that suggests possibilities for drug therapy for kidney disease.

13 Feb 2006

Lupus responds to stem cell transplant therapy

Transplanting patients with blood stem cells that originate from their own bone marrow can induce the remission of life-threatening, treatment-resistant lupus, according to a study that took place at Northwestern Memorial Hospital in Chicago.

13 Feb 2006

Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells

Changes in the tissue environment of the breast that occur after pregnancy promote the metastasis of breast tumor cells. The paper by McDaniel et al., "Remodeling of the mammary microenvironment following lactation promotes breast tumor cell metastasis.

12 Feb 2006

New DNA-based cell adhesion strategy

A new technique in which single strands of synthetic DNA are used to firmly fasten biological cells to non-biological surfaces has been developed by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California at Berkeley.

9 Feb 2006

High blood pressure and kidney disease increase risk for heart disease and stroke in older Americans

Older Americans with high blood pressure and moderate to severe chronic kidney disease have a greater chance of developing heart disease than people with normal kidney function. This finding is one of three in a new paper published in the Feb. 7 issue of the Annals of Internal Medicine.

7 Feb 2006

Alternative method to produce heparin

Researchers at Rensselaer Polytechnic Institute and University of North Carolina at Chapel Hill have discovered an alternative way to produce heparin, a drug commonly used to stop or prevent blood from clotting.

7 Feb 2006

$3.7 million to improve high blood pressure control

The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has launched a $3.7 million, three-year educational effort to improve high blood pressure control nationwide.

5 Feb 2006

Obesity may accelerate the onset of type 1 diabetes in some

Obesity, long known as a cause of type II diabetes, may accelerate the onset of type 1 diabetes in some - but not all - groups of younger patients, according to research at Wake Forest University School of Medicine and six clinical sites nationally.

5 Feb 2006

Hormone hydrocortisone (cortisol) supplementation improves ventilator weaning

Intensive care unit physicians can increase the success of mechanical ventilation weaning and shorten the weaning period by identifying critically ill patients who have adrenal insufficiency and treating them with the hormone hydrocortisone (cortisol).

2 Feb 2006

Weight loss and exercise reduces urinary incontinence in women with prediabetes

Losing a modest amount of weight through dietary changes and increased physical activity reduces the occurrence of urinary incontinence (UI) in women with prediabetes, a condition in which blood glucose levels are higher than normal but not yet diabetic.

27 Jan 2006

$More fractures, less bone density in premenopausal women with diabetes$

More fractures, less bone density in premenopausal women with diabetes

Premenopausal women who have type 1 diabetes should strongly consider preventive screening for osteoporosis, the researchers of a new study on bone density conclude in the February issue of Diabetes Care.

27 Jan 2006

Drug used worldwide doubles risk of kidney failure

A drug approved by the FDA, and sold worldwide for the last 13 years, has now been proven to double a patient's risk of kidney failure, and increase the risk of heart attack, heart failure, and stroke.

26 Jan 2006

New treatment trials for autosomal dominant polycystic kidney disease

The National Institutes of Health (NIH) and the PKD Foundation have launched two treatment trials for autosomal dominant polycystic kidney disease (ADPKD).

25 Jan 2006

Breakthrough in lupus research

A major breakthrough in lupus research - one that may fundamentally change thinking on how the disease affects behavior and cognition - was reported in the January 17, 2006 Proceedings of the National Academy of Sciences (PNAS).

25 Jan 2006

University of Florida researchers restore vitality to cells in lab experiments

University of Florida researchers say primitive cells that act like molecular maintenance men - traveling throughout the body to repair damaged blood vessels - become too rigid to move in patients with diabetes, fueling the disease's vascular complications.

25 Jan 2006