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Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

In a recent study posted to the bioRxiv* preprint server, researchers in the United States described a blocking enzyme-linked immunosorbent assay (ELISA) to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure in animals.

16 Mar 2023

Study implicates gut microbiome and immune response in hospital-acquired infections

In a recent study published in the journal Nature Medicine, researchers at the University of Calgary analyzed the dynamics of fecal microbiota and conducted single-cell profiling of inflammatory responses and systemic immunity to determine associations between gut microbiome dysbiosis and an increased risk of nosocomial infections.

16 Mar 2023

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Testing of ambient air can be used to monitor the community circulation of respiratory pathogens.

16 Mar 2023

Multivariate brain-wide associated studies can be replicable with substantially smaller sample sizes

Since the development of functional magnetic resonance imaging in the 1990s, the reliance on neuroimaging has skyrocketed as researchers investigate how fMRI data from the brain at rest, and anatomical brain structure itself, can be used to predict individual traits, such as depression, cognitive decline, and brain disorders.

16 Mar 2023

Structure of cellular shredders varies according to cell type, study shows

"Miniature shredders" are at work in each cell, disassembling and recycling cell components that are defective or no longer required.

16 Mar 2023

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Acute gastroenteritis afflicts adults of all ages, causing significant suffering and inflicting significant costs on the American healthcare system.

16 Mar 2023

Maternal opioid treatment after delivery not associated with adverse infant outcomes

Infants born to mothers prescribed opioids after delivery, mostly after a cesarean, are at no greater risk of harm shortly after birth than infants of mothers not prescribed opioids, finds a large study from Canada published by The BMJ today.

16 Mar 2023

The US remains a grim leader in preterm births. Why? And can we fix it?

Tamara Etienne's second pregnancy was freighted with risk and worry from its earliest days — exacerbated by a first pregnancy that had ended in miscarriage.

16 Mar 2023

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

16 Mar 2023

New definitions can specify high-risk comorbidity combinations for older surgical patients

A new way to identify more specific, higher-risk groups of older surgical patients can help in clinical decision-making and accurately comparing the performance of one hospital to another, according to research published in the Journal of the American College of Surgeons.

16 Mar 2023

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "AAV1.NT-3 gene therapy prevents age-related sarcopenia."

16 Mar 2023

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.

16 Mar 2023

Customized insole with integrated sensors can measure sole pressure directly in the shoe

Researchers at ETH Zurich, Empa and EPFL are developing a 3D-printed insole with integrated sensors that allows the pressure of the sole to be measured in the shoe and thus during any activity.

15 Mar 2023

Dementia risk is reduced by a Mediterranean diet

A new study in the journal BMC Medicine aimed to analyze the association between dementia incidence and MedDiet adherence as well as assess the interaction between genetic risk and diet for dementia.

15 Mar 2023

Delivering culturally responsive sleep health services to Indigenous adolescents

The University of Queensland and Beyond Blue have partnered to deliver culturally responsive sleep health services to Aboriginal and Torres Strait Islander adolescents in Queensland.

15 Mar 2023

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

A new approach that delivers a "one-two punch" to help T cells attack solid tumors is the focus of a preclinical study by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Mar 2023

Johns Hopkins’ ARISE program may increase the odds of home discharge for hospitalized COVID-19 patients

The Acute Hospital Rehabilitation Intensive Service (ARISE) program, developed in 2020 by the Johns Hopkins Department of Physical Medicine and Rehabilitation (PM&R), may increase the chances of patients hospitalized with COVID-19 getting discharged to their home rather than to a rehabilitation facility that provides post-hospitalization care services.

15 Mar 2023

Hospital News and Research

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

Study implicates gut microbiome and immune response in hospital-acquired infections

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Multivariate brain-wide associated studies can be replicable with substantially smaller sample sizes

Structure of cellular shredders varies according to cell type, study shows

Multiplex PCR panels associated with reduced administration of antibiotics to hospitalized GI patients

Maternal opioid treatment after delivery not associated with adverse infant outcomes

The US remains a grim leader in preterm births. Why? And can we fix it?

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

New definitions can specify high-risk comorbidity combinations for older surgical patients

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

Customized insole with integrated sensors can measure sole pressure directly in the shoe

Dementia risk is reduced by a Mediterranean diet

Delivering culturally responsive sleep health services to Indigenous adolescents

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

Johns Hopkins’ ARISE program may increase the odds of home discharge for hospitalized COVID-19 patients

Teaching young cyclists about the rules of the road to avoid serious childhood accidents

Premature infants in incubators absorb evaporated alcohol from alcohol-based disinfectants

High consumption of common artificial sweetener lowers activation of T-cells in mice

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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