Genes News and Research

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Study provides insight on genes present during trachea and esophagus development

A new study reporting how a network of genes directs the development of the trachea and oesophagus in mice has been published today in eLife.

9 Jun 2020

Immune system can be re-wired to prevent attack of healthy cells, study finds

The body's immune system can be re-wired to prevent it from recognizing its own proteins which, when attacked by the body, can cause autoimmune diseases like multiple sclerosis, a significant new study by UK scientists has found.

9 Jun 2020

Exposure to flame retardant impacts paternal reproduction

A new study from the University of Georgia has shown that exposure to a now-banned flame retardant can alter the genetic code in sperm, leading to major health defects in children of exposed parents.

9 Jun 2020

Happiness could offer protection from gastrointestinal distress

Serotonin, a chemical known for its role in producing feelings of well-being and happiness in the brain, can reduce the ability of some intestinal pathogens to cause deadly infections, new research by UT Southwestern scientists suggests.

9 Jun 2020

High-salt diet may modulate the gut microbiome

Particularly in females with untreated hypertension, reducing salt intake to what's considered a healthier level appears to be good for both their gut microbiome and their blood pressure, scientists report.

9 Jun 2020

New technique to identify genes implicated in the development of malignant brain tumor

Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma - a malignant brain tumor with a very poor prognosis. The study is published in Genome Biology.

9 Jun 2020

Researchers examine bat genome assemblies to find solution for COVID-19

While questions remain about the origin of COVID-19, many scientists now believe the virus spread to humans from bats. Two Texas Tech University researchers are now taking a closer look at whether bats also could offer a solution to the pandemic.

9 Jun 2020

New evidence supports long-debated mode of evolution

A team working at the Smithsonian Tropical Research Institute (STRI) found evidence to support a long-debated mode of evolution, revealing how evolution captures environmental variation to teach old genes new tricks: Sweat bees switch from solitary to social behavior, repurposing ancient sets of genes that originally evolved to regulate the development of other traits.

9 Jun 2020

Metabolic diseases alter ACE2 expression and increase COVID-19 severity

A new study published on the preprint server medRxiv in June 2020 reports that one mechanism for this variable severity is the differential expression of the ACE2 receptor in various metabolic conditions, thereby facilitating viral entry into the host cells.

9 Jun 2020

New Canadian study investigates how cancer adapts its metabolism to overcome therapies

Knowing what cancer will do next could lessen the likelihood of it becoming resistant to treatment. A new Canadian study investigates how cancer adapts its metabolism to potentially overcome therapies still in development.

8 Jun 2020

Chemotherapy and cancer join together to cause neuropathy

Contrary to common medical guidance, chemotherapy does not appear to be the only culprit in neuropathy, a neurological side effect of cancer treatment, a new study says. Cancer itself contributes heavily, too, and the stresses on neurons appear far worse than the sum of the two causes.

8 Jun 2020

Better testing could lead to improved treatments for a specific type of ovarian cancer

Scientists have found that a specific type of ovarian cancer could possibly benefit from existing platinum-based chemotherapy and new DNA repairing treatments, following better testing.

8 Jun 2020

Researchers confirm new therapeutic target for myelodysplastic syndrome

A research group from Kumamoto University, Japan analyzed the pathophysiology of myelodysplastic syndrome (MDS), a blood cancer that presents often in the elderly, and found the presence of the transcription factor RUNX3, thereby revealing a cancer growth function for what had been considered a tumor suppressor.

8 Jun 2020

Study identifies potential biomarker for prescreening donor's stem cells

A new study released today in STEM CELLS addresses a significant problem that has been confronting human mesenchymal stem cells (hMSCs) therapy.

8 Jun 2020

Genetic studies analyze genome-wide set of genetic variants in different individuals

Genome-wide association studies (GWAS) analyze a genome-wide set of genetic variants in different individuals to see if any are associated with a trait or disease.

8 Jun 2020

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

By looking into zinc-finger antiviral proteins (ZAP), a new study from Germany and the United Kingdom (UK) and available on the preprint server bioRxiv suggests that zoonotic transmission of a coronavirus with a specific genetic make-up facilitated the pandemic spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also its sensitivity to interferons.

7 Jun 2020

Study investigates combined effects of cancer therapy and inherited genetics

Scientists at St. Jude Children's Research Hospital are studying the combined effect of cancer treatments and inherited mutations in DNA-repair genes.

5 Jun 2020

DNA sequencing and analysis of drug-resistant bacteria set up in the Philippines

Antibiotic resistance surveillance in the Philippines has moved into the genomic era, enabling better tracking of dangerous bacteria. Researchers at the Centre for Genomic Pathogen Surveillance (CGPS housed at the Wellcome Sanger Institute and The Big Data Institute, University of Oxford), and the Philippine Research Institute for Tropical Medicine, set up local DNA sequencing and analysis of drug resistant bacteria in the Philippines.

5 Jun 2020

Study: MafB protein may protect against renal failure

Focal segmental glomerulosclerosis (FSGS) is a common cause of steroid-resistant nephrotic syndrome, a type of kidney disease that is accompanied by massive urinary protein loss and that may progress to end-stage renal disease.

5 Jun 2020

Researchers use single-cell-resolution technologies to map brain genes in humans

A group of scientists led by Philipp Khaitovich, a professor at Skoltech, conducted a large-scale study of gene expression in 33 different brain regions of humans, chimpanzees, macaques and bonobos using the single-cell-resolution transcriptomics technologies and made a map of the different brain regions with their specific cell structures.

5 Jun 2020

Genes News and Research

Study provides insight on genes present during trachea and esophagus development

Immune system can be re-wired to prevent attack of healthy cells, study finds

Exposure to flame retardant impacts paternal reproduction

Happiness could offer protection from gastrointestinal distress

High-salt diet may modulate the gut microbiome

New technique to identify genes implicated in the development of malignant brain tumor

Researchers examine bat genome assemblies to find solution for COVID-19

New evidence supports long-debated mode of evolution

Metabolic diseases alter ACE2 expression and increase COVID-19 severity

New Canadian study investigates how cancer adapts its metabolism to overcome therapies

Chemotherapy and cancer join together to cause neuropathy

Better testing could lead to improved treatments for a specific type of ovarian cancer

Researchers confirm new therapeutic target for myelodysplastic syndrome

Study identifies potential biomarker for prescreening donor's stem cells

Genetic studies analyze genome-wide set of genetic variants in different individuals

Zinc-finger antiviral protein makes SARS-CoV-2 highly susceptible to interferons

Study investigates combined effects of cancer therapy and inherited genetics

DNA sequencing and analysis of drug-resistant bacteria set up in the Philippines

Study: MafB protein may protect against renal failure

Researchers use single-cell-resolution technologies to map brain genes in humans

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