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Study opens up prospects for using virotherapy to treat central nervous system tumors

In a study conducted at the University of São Paulo's Human Genome and Stem Cell Research Center (HUG-CELL) in Brazil, serial systemic injections of zika virus into mice with brain tumors destroyed the cancer without causing neurological damage or injuring other organs, and increased the animals' survival rate.

11 Jan 2022

Study offers new evidence on how childhood immunometabolic risk factors may lead to depression, psychosis

A growing body of research suggests that early-life infection, inflammation, and metabolic changes could contribute to psychiatric disorders – perhaps via effects during critical periods of brain development.

11 Jan 2022

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

11 Jan 2022

First patient-derived stem cell model developed for studying oculocutaneous albinism

Researchers at the National Eye Institute have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA).

11 Jan 2022

VarLOCK approach for rapid detection of SARS-CoV-2 variants of concern and wastewater monitoring

A recent study discussed the expansion of the SARS-CoV-2 CRISPR-Cas detection technology (SHERLOCK) into Variant-specific SHERLOCK (VarLOCK) assays to accurately differentiate between the newly emerging SARS-CoV-2 variants of concern.

11 Jan 2022

Exploring the kinetics of SARS-CoV-2 Marseille-4 variant

In a new study, researchers determined the nature and dynamics of mutations associated with the SARS-CoV-2 French Marseille-4 variant during 10 months from its onset, and concluded that the heterogenicity associated with a SARS-CoV-2 lineage can possibly predict the end of an outbreak.

11 Jan 2022

Study reveals genomic regions that could help understand obesity

A new study has helped to shine light on the genetic pathways underlying obesity. The findings could help develop more personalized ways to help people maintain a healthy weight.

11 Jan 2022

Analyzing the evolution of SARS-CoV-2 RNA polymerase in humans

In a new study, researchers examined the impact of mutations on the structural thermodynamic stability (structural stability) of SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) through free energy computation.

11 Jan 2022

Low birth weight among IVF babies unlikely to be driven by the reproductive technology

Children conceived through medically assisted reproduction are more likely to be born premature and are at greater risk of being born small than naturally conceived babies, according to new research published today by the UCL Centre for Longitudinal Studies in collaboration with the University of Utah.

11 Jan 2022

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

A new preprint describes a single-step molecular diagnostic test for the presence of SARS-CoV-2 infection caused by the Omicron variant that is behind the unprecedented rise in cases over the last few weeks.

11 Jan 2022

Unique combination of nanomaterials in DNA biosensor enables easier SARS-CoV-2 detection

A recent paper that was published in the Talanta journal dedicated to original reports in pure and applied analytical chemistry presents for the first time the combination of two different nanomaterials – gold nanomaterials (AuNMs) and CDs for the development of an improved electrochemiluminescence (ECL) DNA biosensor.

10 Jan 2022

Researchers create a DNA-based fluorescent nanoantenna to monitor the motions of proteins

Researchers at Université de Montréal have created a nanoantenna to monitor the motions of proteins. Reported this week in Nature Methods, the device is a new method to monitor the structural change of proteins over time – and may go a long way to helping scientists better understand natural and human-designed nanotechnologies.

10 Jan 2022

Hybrid incompatibilities can be dependent on the environment, fish study suggests

You're likely familiar with the idea of the sterile mule: a hybrid animal born of a horse and a donkey that is unable to breed.

10 Jan 2022

Newly developed risk scores can help identify childhood obesity risk

Newly developed risk scores synthesize genetic information into an easy-to-interpret metric that could help clinicians identify young children most at risk of developing obesity.

10 Jan 2022

New neural circuits regulating spatial learning, memory in the brain's hippocampal formation discovered

A research team led by University of California, Irvine has discovered new neural circuits that regulate spatial learning and memory in the brain's hippocampal formation.

10 Jan 2022

Researchers illuminate the molecular landscape and clinical features of rare kidney cancer

Translocation renal cell carcinoma (tRCC) is a rare and aggressive form of kidney cancer. It accounts for about 5 percent of all renal cell carcinomas in adults and about 50 percent in children.

10 Jan 2022

Researchers identify gene expression signatures linked to suicide risk

Is risk of suicide in our genes? Findings of an international scientific team led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that gene expression studies could offer insights into the underlying causes of suicide, a highly complex public health problem that takes the lives of more than 800,000 people each year worldwide.

10 Jan 2022

Genetic News and Research

Study opens up prospects for using virotherapy to treat central nervous system tumors

Study offers new evidence on how childhood immunometabolic risk factors may lead to depression, psychosis

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

First patient-derived stem cell model developed for studying oculocutaneous albinism

VarLOCK approach for rapid detection of SARS-CoV-2 variants of concern and wastewater monitoring

Exploring the kinetics of SARS-CoV-2 Marseille-4 variant

Study reveals genomic regions that could help understand obesity

Analyzing the evolution of SARS-CoV-2 RNA polymerase in humans

Low birth weight among IVF babies unlikely to be driven by the reproductive technology

Single-step RT-PCR for SARS-CoV-2 Omicron variant detection in respiratory samples

Unique combination of nanomaterials in DNA biosensor enables easier SARS-CoV-2 detection

Researchers create a DNA-based fluorescent nanoantenna to monitor the motions of proteins

Hybrid incompatibilities can be dependent on the environment, fish study suggests

Newly developed risk scores can help identify childhood obesity risk

New neural circuits regulating spatial learning, memory in the brain's hippocampal formation discovered

Researchers illuminate the molecular landscape and clinical features of rare kidney cancer

Researchers identify gene expression signatures linked to suicide risk

New genetic mechanism that can cause severe male infertility identified

Scientists shine new light on the complexity of vitamin B12 diseases

T cells induced by common cold coronaviruses play a protective role against COVID-19 infection

Sequencing & Genomics: Elevating Science and Healthcare eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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