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Study demonstrates long-term safety and clinical benefit of combination therapy for cystic fibrosis

Patients with cystic fibrosis (CF) face difficulty breathing and a decline in lung function and are at risk of early death. CF is an inherited condition that results in thick mucus build-up, persistent infection and inflammation in the lungs.

15 Mar 2023

Vitamin A-rich diet may reduce risk of developing asparaginase-associated pancreatitis in ALL patients

Consuming a diet rich in vitamin A or its analogs may help prevent children and young adults with acute lymphoblastic leukemia (ALL) reduce their risk of developing painful pancreas inflammation during chemotherapy treatment.

15 Mar 2023

Research uncovers a possible explanation for sex differences in pancreatic cancer

Immunotherapy is an effective form of therapy for different types of cancer. However, for pancreatic cancer, its effect is limited and differs between men and women.

15 Mar 2023

Vaccination protects lupus patients from contracting COVID-19

Researchers determine the risk of COVID-19 and possibility of severe sequelae in patients with systemic lupus erythematosus and the general population.

14 Mar 2023

New guideline focuses on the timing of hip and knee arthroplasty

The American College of Rheumatology and the American Association of Hip and Knee Surgeons released a summary of its new guideline titled "the Optimal Timing of Elective Hip or Knee Arthroplasty for Patients with Symptomatic Moderate to Severe Osteoarthritis or Osteonecrosis Who Have Failed Nonoperative Therapy."

14 Mar 2023

Study finds better breast cancer screening outcomes with tomosynthesis than mammography

In a study of over a million women, digital breast tomosynthesis (DBT) showed improved breast cancer screening outcomes over screening with standard digital mammography alone.

14 Mar 2023

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

The hormone glucose-dependent insulinotropic polypeptide (GIP) is considered obesogenic. In contrast, GIP receptor agonists (GIPRAs) have shown reduced feeding and body weight in an obese mouse model. Therefore, the precise effects exerted by GIP and GIPRAs remain elusive.

14 Mar 2023

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

A growing body of evidence is showing that the healthy gut microbiome – a community of microorganisms that live together in the gut – influences many aspects of human growth and development, especially during adolescence.

14 Mar 2023

Hunger hormone can increase the heart's pump capacity in patients with heart failure

A clinical study by researchers at Karolinska Institutet and Karolinska University Hospital in Sweden shows that the hunger hormone ghrelin can increase the heart's pump capacity in patients with heart failure.

14 Mar 2023

Facility-level disparities linked to racial health inequality among prostate cancer patients

Racial minorities in the United States are less likely to receive treatment for prostate cancer and, overall, have worse survival outcomes compared to individuals who are white.

14 Mar 2023

Insufficient sleep results in decreased antibody response to vaccination

In reviewing data from previous studies, a team lead by researchers at the University of Chicago and the French National Institute of Health and Medical Research (Inserm) found that individuals who had fewer than six hours of sleep per night in the days surrounding vaccination had a blunted antibody response.

14 Mar 2023

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

A type of immune therapy called chimeric antigen receptor (CAR)-T cell therapy has revolutionized the treatment of multiple types of blood cancers but has shown limited efficacy against glioblastoma - the deadliest type of primary brain cancer - and other solid tumors.

14 Mar 2023

Hospital News and Research

Study demonstrates long-term safety and clinical benefit of combination therapy for cystic fibrosis

Vitamin A-rich diet may reduce risk of developing asparaginase-associated pancreatitis in ALL patients

Research uncovers a possible explanation for sex differences in pancreatic cancer

Vaccination protects lupus patients from contracting COVID-19

New guideline focuses on the timing of hip and knee arthroplasty

Study finds better breast cancer screening outcomes with tomosynthesis than mammography

Long-acting GIPRA inhibits feeding and lowers body weight in mice with diet-induced obesity

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

Hunger hormone can increase the heart's pump capacity in patients with heart failure

Facility-level disparities linked to racial health inequality among prostate cancer patients

Insufficient sleep results in decreased antibody response to vaccination

Correcting abnormalities in solid tumor's blood vessels can improve efficacy of CAR-T cell therapy

Jersey Shore University Medical Center redesignated as a Baby-Friendly Hospital

Specific enzyme produced in liver cancer cells could turn a molecule into potential anticancer drug

Host immune system forms small lesions in the intestines in response to bacterial infection

Do the symptom profiles among children with SARS-CoV-2 infection differ by variant type?

The burden of Clostridioides difficile infections in the United States

AI-assisted analysis helps find new targets for CAR-T cell therapy against acute myeloid leukemia

What are the risk factors associated with post-acute SARS-CoV-2 infection?

Innate immune molecule could be at the root of ALS

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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