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Amgen wins Scrip Best New Drug award for Prolia

Amgen is pleased to announce that it has won the Best New Drug award for Prolia™ (denosumab), a novel treatment approved in the United States (U.S.) for women with postmenopausal osteoporosis at high risk for fracture, at the 2010 Scrip Awards ceremony Nov. 4 in London. Named one of TIME's Top 10 Medical Breakthroughs of 2009, Prolia is the first treatment specifically designed to target osteoclasts, the cells that break down bone.

8 Nov 2010

Prolonged separation from mother increases risk of breast cancer in young mice

Young mice that experienced the psychosocial stress of prolonged separation from their mothers had a higher incidence and faster onset of breast tumors compared with young mice who did not experience this stressful life event. Specifically, neonatal mice separated from their mothers for a prolonged period of time developed mammary tumors twice as fast as mice that experienced short or no maternal separation.

8 Nov 2010

FDA reviews GSK's response to Complete Response letter for Horizant

GlaxoSmithKline and XenoPort, Inc. announced today that the U.S. Food and Drug Administration (FDA) has accepted for review GSK's response to FDA's Complete Response letter for Horizant (gabapentin enacarbil) Extended-Release Tablets. Horizant is under review for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS).

8 Nov 2010

Americans sicker but live longer than the English: Study

According to a new study in the journal Demographics, and elderly American is not quite as healthy as his English counterpart, but does live just as long, if not longer. The study found that Americans aged 55 to 64 and 70 to 80 had higher rates of chronic diseases than same-aged English people, but they died at about the same rate. Americans aged 65 and older could be sicker than their English peers but lived longer.

5 Nov 2010

New findings on mitochondrial haplogroups associated with successful aging to be presented at ASHG Meeting

Thousands of the world's top scientists and clinicians in the human genetics field will convene to present their latest research findings at the American Society of Human Genetics (ASHG) 60th Annual Meeting, on November 2-6, 2010, in Washington, D.C.

4 Nov 2010

Medicare reimbursement cuts lead to decline in unnecessary or inappropriate care

When Medicare policy changes led to reductions in reimbursement for hormonal treatment of prostate cancer, there was a sharp decline in its use among patients not likely to benefit from the treatment. But among patients for whom the therapy is clearly beneficial, doctors continued to prescribe it at the same rate, according to a new study.

4 Nov 2010

Cerebral palsy risk doubles with IVF: Study

There is now evidence that rates of cerebral palsy are higher among children born via in vitro fertilization (IVF). There has been speculation that the parents’ infertility could be a reason but this new study is the first that links the procedure to the condition.

3 Nov 2010

Labor-HHS bill to provide 3.2% increase in fiscal year 2011 for NIH

Despite innovative cancer research being presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, as well as numerous other conferences organized by the American Association for Cancer Research each year, the pace of scientific discovery in cancer research will slow if Congress does not pass the pending appropriations bill for fiscal year 2011.

3 Nov 2010

Study finds infertility treatment does not increase risk of cerebral palsy in IVF/ICSI children

Doctors have known for some time that children born after fertility treatments such as in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) are at increased risk of cerebral palsy. However, it was not known whether this risk was due to the treatment itself, the higher frequency of preterm or multiple births, or a mechanism associated with couples' underlying infertility.

3 Nov 2010

Study: Illnesses and injuries that restrict activity linked to worsening functional ability in older adults

A study by Yale School of Medicine researchers reveals that the illnesses and injuries that can restrict the activity of older adults or land them in the hospital are linked to worsening functional ability, especially among those who are physically frail. The report appears in JAMA's November 3 theme issue on aging.

3 Nov 2010

Liver-related mortality ranks #4 for people between ages of 45 and 64

Statistics from the Centers for Disease Control and Prevention (CDC) rank mortality related to chronic liver disease and cirrhosis as the 12th most common cause of death in adults in the U.S. Using a modified definition that includes diseases such as viral hepatitis, liver cancer and obesity-related fatty liver disease, Mayo Clinic-led researchers have found that liver-related mortality is as high as fourth for some age groups, and eighth overall.

2 Nov 2010

Study finds elderly women at high risk for inappropriate urinary catheter utilization

Elderly women are at high risk for inappropriate urinary catheter utilization in emergency departments, according to a new study in the November issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).

2 Nov 2010

Study finds inhaled corticosteroids increase type 2 diabetes risk

Patients taking inhaled corticosteroids are at increased risk of developing type 2 diabetes, and more so with higher doses, say researchers at the Jewish General Hospital's Lady Davis Institute for Medical Research (LDI) In Montreal. The risk is of special concern for patients suffering from chronic obstructive pulmonary disorder (COPD), and much less significant for asthmatics.

2 Nov 2010

AACR announces launch of new journal, Cancer Discovery

The American Association for Cancer Research announces the launch of its newest journal, Cancer Discovery, which will publish high-impact, peer-reviewed articles describing major advances in basic and clinical research. Its unique format will feature game-changing research, review articles, perspectives and commentaries, news, and "Research Watch" summaries of important journal articles. Cancer Discovery is a new addition to the AACR's robust publication program.

30 Oct 2010

Study suggests microRNA binding site helps improved prognosis of colorectal cancer at early stage

A variant site linked to poor outcome in advanced colorectal cancer has now been found to predict improved prognosis in early stages of cancer, according to research presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held Oct. 27-30, 2010.

29 Oct 2010

Phytonutrient Report says Americans do not consume enough fruits and vegetables

The majority of Americans report getting a cold or flu in the past year, and more than a third say they'll make lifestyle changes to prevent getting sick again this year. However, 40 percent of Americans don't plan to take what is arguably the easiest and tastiest step to help potentially prevent illness this cold and flu season eat more fruits and vegetables daily.

29 Oct 2010

Novel small molecule inhibitors may provide new therapy for colon cancer

Researchers are one step closer to providing a new therapy for colon cancer, after findings revealed that a small molecule focal adhesion kinase (FAK) inhibitor known as Y15 effectively blocked cell viability, promoted detachment and apoptosis, and decreased tumor growth in mice. These findings were presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held Oct. 27-30, 2010.

29 Oct 2010

New biobank at Qatar helps research of major diseases

A "biobank" of samples and clinical measurements from tens of thousands of people is to be established in Qatar to help scientists understand the causes of major diseases and develop new treatments, it is announced today.

29 Oct 2010

Miami Miller School receives grant to study impact of GenerationOne's mobile solution on heart failure patients

The James and Esther King Biomedical Research Program has awarded the University of Miami Miller School of Medicine Geriatrics Institute a $100,000 grant for a year-long study on the impact of GenerationOne's Mobile Heath Solution on heart failure patients.

29 Oct 2010

Researchers identify small-molecule inhibitors that effectively target FAK enzyme in colon cancer

Researchers have identified two small-molecule inhibitors that effectively targeted the focal adhesion kinase (FAK), an enzyme present in certain cancers that helps tumors thrive and survive.

29 Oct 2010

Epidemiology News and Research

Amgen wins Scrip Best New Drug award for Prolia

Prolonged separation from mother increases risk of breast cancer in young mice

FDA reviews GSK's response to Complete Response letter for Horizant

Americans sicker but live longer than the English: Study

New findings on mitochondrial haplogroups associated with successful aging to be presented at ASHG Meeting

Medicare reimbursement cuts lead to decline in unnecessary or inappropriate care

Cerebral palsy risk doubles with IVF: Study

Labor-HHS bill to provide 3.2% increase in fiscal year 2011 for NIH

Study finds infertility treatment does not increase risk of cerebral palsy in IVF/ICSI children

Study: Illnesses and injuries that restrict activity linked to worsening functional ability in older adults

Liver-related mortality ranks #4 for people between ages of 45 and 64

Study finds elderly women at high risk for inappropriate urinary catheter utilization

Study finds inhaled corticosteroids increase type 2 diabetes risk

AACR announces launch of new journal, Cancer Discovery

Study suggests microRNA binding site helps improved prognosis of colorectal cancer at early stage

Phytonutrient Report says Americans do not consume enough fruits and vegetables

Novel small molecule inhibitors may provide new therapy for colon cancer

New biobank at Qatar helps research of major diseases

Miami Miller School receives grant to study impact of GenerationOne's mobile solution on heart failure patients

Researchers identify small-molecule inhibitors that effectively target FAK enzyme in colon cancer

Industry Focus: Infectious Diseases eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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