B Cell News and Research

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Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

The Tecan Group and Oxford Nanopore Technologies plc (Oxford Nanopore) today announce their collaboration to drive easier high-throughput nanopore library preparation in an automated, hands-free fashion.

From Tecan 27 Feb 2023

New method can potentially catch COVID-19 infections quickly with near-perfect accuracy

By inspecting the body's immune response at a molecular level, a research team has developed a new way to test patients for COVID-19.

27 Feb 2023

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Nearly 100% of cases of amyotrophic lateral sclerosis - the progressive, fatal neurodegenerative disease known as ALS or Lou Gherig's disease - involve the buildup of a protein called TDP-43.

27 Feb 2023

Different cellular building blocks are not produced at the same time, research shows

Textbooks will tell you that in dividing cells, the production of new DNA peaks during the S-phase, while production of other macromolecules, such as proteins, lipids, and polysaccharides, continues at more or less the same level.

27 Feb 2023

Large cell therapy trial in patients with chronic heart failure shows promising results

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

27 Feb 2023

Popular artificial sweetener associated with elevated risk of heart attack and stroke, study shows

New Cleveland Clinic research showed that erythritol, a popular artificial sweetener, is associated with an increased risk of heart attack and stroke.

27 Feb 2023

Innovative methodology to detect viral RNA

Experts from the University of Barcelona, the Institute for Advanced Chemistry of Catalonia, the Institute of Microelectronics of Barcelona and the Aragon Nanoscience and Materials Institute of Aragon —a joint institute of the CSIC and the University of Zaragoza— have developed a new method to detect RNA viruses based on the triplex-forming probe technology.

27 Feb 2023

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

The number of specialized immune cells available for fighting skin cancer doubled when a new treatment blocked their escape from melanoma tumors, experiments in mice and human cells show.

27 Feb 2023

Researchers explore potential new target for cancer immunotherapy

A new study posted to the bioRxiv* preprint server, focused on the role of YAP in regulating MHC-I APM expression within tumor cells.

27 Feb 2023

Innate lymphoid cells educate alveolar macrophages following exposure to different viruses

A study conducted by researchers at the University of Liège on group 2 innate lymphoid cells (or ILC2s) shows that the functional reprogramming of these cells following their exposure to viruses allows our body to react differently to exposure to certain respiratory allergens.

27 Feb 2023

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

Researchers explored the connection between the metabolic function of the gut microbiota, its composition, and immune response to SARS-CoV-2 vaccination in IBD patients.

27 Feb 2023

What is the effect of maternal circulating amino acids on offspring birthweight?

Researchers examined the effect of serum levels of 20 amino acids in a mother during pregnancy on offspring birthweight in a two-sample summary data Mendelian randomization framework.

27 Feb 2023

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Researchers assessed T-cell tolerance checkpoints observed in atherosclerosis.

27 Feb 2023

Rapid AAV Titer for Bioprocessing in Gene Therapy

In this article, News-Medical talks to Sartorius about biosensing and bioprocessing in gene therapy, while also discussing the various products Sartorius produces in order to aid in this.

From Sartorius 27 Feb 2023

High throughput device isolates and classifies metabolically active CTCs

Researchers from the University of Technology Sydney have developed a new device that can detect and analyze cancer cells from blood samples, enabling doctors to avoid invasive biopsy surgeries, and to monitor treatment progress.

27 Feb 2023

Novel software tool helps analyze animal behaviors

A team from the University of Michigan has developed a new software tool to help researchers across the life sciences more efficiently analyze animal behaviors.

25 Feb 2023

Significance of mathematical modeling in understanding complex biological processes

Humans and animals detect different stimuli such as light, sound, and odor through nerve cells, which then transmit the information to the brain. Nerve cells must be able to adjust to the wide range of stimuli they receive, which can range from very weak to very strong. To do this, they may become more or less sensitive to stimuli (sensitization and habituation), or they may become more sensitive to weaker stimuli and less sensitive to stronger stimuli for better overall responsiveness (gain control). However, the exact way this happens is not yet understood.

25 Feb 2023

Virus encounter educates human immune system, says study

25 Feb 2023

Novel microfluidic model mimics a rare genetic disorder

Our bodies are made up of 60,000 miles of complex pipes that play a vital role in transporting nutrients throughout our bodies, performing waste disposal, and supplying our organs with fresh oxygen and blood.

24 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

B Cell News and Research

Tecan and Oxford Nanopore build alliance to create automated, seamless and fully compatible nanopore sequencing library preparation for any-length fragments of native DNA/RNA

New method can potentially catch COVID-19 infections quickly with near-perfect accuracy

Common RNA modification plays a key role in TDP-43-related neurodegeneration in ALS

Different cellular building blocks are not produced at the same time, research shows

Large cell therapy trial in patients with chronic heart failure shows promising results

Popular artificial sweetener associated with elevated risk of heart attack and stroke, study shows

Innovative methodology to detect viral RNA

Combining a chemical blocker of immune cell exit with immunotherapy stops skin cancer growth

Researchers explore potential new target for cancer immunotherapy

Innate lymphoid cells educate alveolar macrophages following exposure to different viruses

Can the gut microbiota and metabolome explain variation in anti-SARS-CoV-2 vaccination responses in immunosuppressed IBD patients?

What is the effect of maternal circulating amino acids on offspring birthweight?

Study supports the concept of atherosclerosis as a T-cell autoimmune disease targeting the arterial wall

Rapid AAV Titer for Bioprocessing in Gene Therapy

High throughput device isolates and classifies metabolically active CTCs

Novel software tool helps analyze animal behaviors

Significance of mathematical modeling in understanding complex biological processes

Virus encounter educates human immune system, says study

Novel microfluidic model mimics a rare genetic disorder

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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