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Mayo Clinic study evaluates trends in risk profiles, patient outcomes for coronary revascularization

The most common type of heart disease -- coronary artery disease -- affects 6.7% of adults and accounts for 20% of 2 in 10 deaths of adults under age 65.

14 Feb 2020

UIC researchers discover unique organ-specific signatures for endothelial cells

Researchers from the University of Illinois at Chicago have discovered that endothelial cells - those that create the inner lining of blood vessels - have unique genetic signatures based on their location in the body.

14 Feb 2020

New study describes inflammatory reaction in lab-developed human astrocytes

Astrocytes are neural cells with many important functions in the nervous system. The inflammation of these cells occurs in brain infections and neurodegenerative disorders, a process called astrogliosis.

14 Feb 2020

Inflammation detected in the brains of veterans with Gulf War Illness

In a new discovery, researchers at Massachusetts General Hospital have detected widespread inflammation in the brains of veterans diagnosed with Gulf War Illness.

13 Feb 2020

Children with suspected appendicitis need better care, finds study

A new study published in the journal The Lancet Child & Adolescent Health reports that suspected appendicitis in children is not only among the most common pediatric conditions but often wrongly treated. The researchers found that literally, hundreds of children in the UK were having their appendices taken out unnecessarily.

13 Feb 2020

Scientists isolate individual cells that cause autoimmune disease

Researchers have homed in on the cells that cause an autoimmune disease to arise in the body. The study, published in the journal Cell in February 2020, as part of the far-seeing Hope Research project, reports on the discovery.

13 Feb 2020

Immune cells count each other in order to decide whether to attack

A new study published in the journal Nature Communications in February 2020 shows that immune cells consult and coordinate with each other at the site of activity to bring about a balanced but adequate reaction and stave off the threat.

13 Feb 2020

'Smart' bandages could facilitate healing of hard-to-treat wounds

Chronic and non-healing wounds--one of the most devastating complications of diabetes and the leading cause of limb amputation--affects millions of Americans each year. Due to the complex nature of these wounds, proper clinical treatment has been limited.

13 Feb 2020

Circulating ceramide ratios may be useful predictors of future dementia risk

Novel blood-based biomarkers for dementia could identify disease at an early preclinical stage, serve as surrogate outcomes for clinical trials of investigational therapies and even identify future potential therapeutic targets.

13 Feb 2020

Acid reflux drug may be a promising therapy to reduce preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of the drugs in mice.

13 Feb 2020

Macrophages consult with neighbors before making decisions

Many people consult their friends and neighbors before making a big decision. It turns out that cells also are consulting their neighbors in the human body.

13 Feb 2020

Gum disease linked to stroke

A pair of new studies has revealed that gum diseases could be associated with a heightened risk of strokes and atherosclerosis of hardening of the arterial walls. The results of this new research are to be presented at the American Stroke Association's International Stroke Conference 2020 between 19th and 21st of February 2020 in Los Angeles.

12 Feb 2020

UChicago researchers develop first accurate mouse model of celiac disease

Researchers at the University of Chicago have developed the first truly accurate mouse model of celiac disease. The animals have the same genetic and immune system characteristics as humans who develop celiac after eating gluten. This provides a vital research tool for developing and testing new treatments for the disease.

12 Feb 2020

Exploring common tech-related injuries

Nearly half of all U.S. adults say they can't live without their smartphones, according to the Pew Research Center. But what happens when our fondness for the latest electronic gadgets creates more pain than gain?

12 Feb 2020

Vitamin D deficiency in postmenopausal women linked to disc degeneration and lower back pain

Lumbar disc degeneration and resulting lower back pain become greater concerns with age and disproportionately affect women more than men, likely as a result of decreasing estrogen levels during menopause.

12 Feb 2020

Microbiome can predict a person's chronological age

Our microbiomes - the complex communities of microbes that live in, on and around us - are influenced by our diets, habits, environments and genes, and are known to change with age.

11 Feb 2020

New technique may yield insights on the immune response to intestinal parasite infections

A new technique may help scientists study the body's immune response to intestinal parasite infections one gut cell at a time, according to a study published today in eLife.

11 Feb 2020

Macrophages migrate from the blood to attack brain tissue shortly after stroke

Macrophages are part of the innate immune system and essential for brain development and function. Using a novel method, scientists from Jena University Hospital, the University of Bonn and the Memorial Sloan Kettering Cancer Center in New York (USA) succeeded in visualizing macrophages that were formed in the bone marrow.

11 Feb 2020

NSF CAREER award supports research into biomaterial that promotes osteochondral tissue regeneration

If you're able to walk without pain, give a silent shout-out to your cartilage.

11 Feb 2020

Research shows how the brain's immune system could be activated to improve memory

When it comes to memory, immune cells are known as the "bad cops" of the brain. But new research shows they could also be turned into "good cops" to power memory and learning.

11 Feb 2020