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Heavy drinking associated with faster decline in cognitive function in middle-aged men

Middle-aged men who drink more than 36 grams of alcohol, or two and a half US drinks per day, may speed their memory loss by up to six years later on, according to a study published in the January 15, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology.

16 Jan 2014

Cognigram can detect early signs of MCI and Alzheimer’s disease

For patients over the age of 50, a routine physical exam at the doctor’s office typically covers a wide spectrum of medical biomarkers with one glaring exception, cognitive health. Unless there have been unusual mental changes or challenges in their daily life, tests of a patient’s attention, memory or brain processing speed is usually not part of a check-up.

15 Jan 2014

Less gray matter in brain not linked to reading disabilities in people with dyslexia

In people with dyslexia, less gray matter in the brain has been linked to reading disabilities, but now new evidence suggests this is a consequence of poorer reading experiences and not the root cause of the disorder.

15 Jan 2014

Hepatitis C infection varies widely among different Hispanic groups in the U.S.

The first study of hepatitis C infection among different Hispanic groups in the U.S. has found that infection with the virus varies widely, with Puerto Rican Hispanics much more likely than other groups to be infected. The study, led by researchers at Albert Einstein College of Medicine of Yeshiva University, highlights which Hispanic populations would benefit most from increased hepatitis C testing and treatment.

15 Jan 2014

Ultrasound can modulate brain activity to heighten sensory perception in humans

Whales, bats, and even praying mantises use ultrasound as a sensory guidance system - and now a new study has found that ultrasound can modulate brain activity to heighten sensory perception in humans.

13 Jan 2014

At-home paper test can help spot early symptoms of cognitive issues

The Self-Administered Gerocognitive Examination (SAGE test), which takes less than 15 minutes to complete, is a reliable tool for evaluating cognitive abilities. Findings by researchers at The Ohio State University Wexner Medical Center confirming the feasibility and efficiency of the tool for community screening large numbers of people are published in the January issue of The Journal of Neuropsychiatry and Clinical Neurosciences.

13 Jan 2014

FDA approves Farxiga tablets to improve glycemic control in adults with type 2 diabetes mellitus

AstraZeneca and Bristol-Myers Squibb Company announced the U.S. Food and Drug Administration approved Farxiga™ [far-SEE-ga] (dapagliflozin), a once-daily oral treatment indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

13 Jan 2014

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Today the scientific journal Neuron published results on the Roche-designed Brain Shuttle technology that efficiently transfers investigational antibodies from the blood through the blood-brain barrier (BBB) into the brain in preclinical models.

10 Jan 2014

Neurovance announces interim results from phase 2a pilot study of EB-1020 SR in patients with all subtypes of ADHD

Neurovance Inc. today announced interim results from its phase 2a pilot study of EB-1020 SR in adult patients with all subtypes of ADHD. With the four week trial fully enrolled and dosing completed in the majority of patients, the results indicate a statistically significant improvement in ADHD symptoms.

10 Jan 2014

Mild electronic stimulation therapy to upper airway during sleep effective in reducing OSA

Results published in a new study in the Jan. 9 issue of the New England Journal of Medicine report that mild electronic stimulation therapy to the upper airway during sleep is effective in reducing obstructive sleep apnea (OSA).

9 Jan 2014

Montreal researchers identifies two specific key players in growth of GBM

Glioblastoma (GBM) is the most common and deadly form of primary malignant brain cancer accounting for approximately 15% of all brain tumours and occurring mostly in adults between the ages of 45 and 70.

9 Jan 2014

Epilepsy drug taken during pregnancy not linked with development problems for preschoolers

A new study finds that the epilepsy drug levetiracetam appears not to be associated with thinking, movement and language problems for preschool children born to mothers who took the drug during pregnancy, although the drug valproate was associated with some difficulties in preschoolers.

8 Jan 2014

Nociceptin in brain naturally moderates effects of stress

Collaborating scientists at The Scripps Research Institute (TSRI), the National Institutes of Health (NIH) and the University of Camerino in Italy have published new findings on a system in the brain that naturally moderates the effects of stress.

8 Jan 2014

Experts gather to bring mindfulness in youths

Experts in the field of mindfulness will gather in San Diego from Feb. 7-9 to share the latest advancements in education, clinical care and research as it applies to the healthy development of youth through the application of meditation.

8 Jan 2014

IDMC recommends early stopping of Phase 3 study of ibrutinib in treatment of CLL/SLL

Janssen-Cilag International NV today announced the early stopping of PCYC-1112-CA, the Phase 3 study of ibrutinib in the treatment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, based on the recommendation of an Independent Data Monitoring Committee, which concluded that the study showed a significant difference in progression-free survival as compared to the control, the primary endpoint of the study.

8 Jan 2014

Study sheds light on the biological underpinnings of obesity

A new neuroscience study sheds light on the biological underpinnings of obesity. The in vivo study, published in the January 8 issue of the Journal of Neuroscience, reveals how a protein in the brain helps regulate food intake and body weight. The findings reveal a potential new avenue for the treatment of obesity and may help explain why medications that are prescribed for epilepsy and other conditions that interfere with this protein, such as gabapentin and pregabalin, can cause weight gain.

7 Jan 2014

Hotspots of fuel consumption in adult brain also show key characteristics of developing brain

Although brain growth slows as individuals age, some regions of the brain continue to develop for longer than others, creating new connections and remodeling existing circuitry.

7 Jan 2014

Study identifies strategy to help women climb the academic ladder

More women are choosing science careers, yet women are notoriously underrepresented in senior academic positions—often because they abandon their careers due to pessimism about advancement. New research suggests that putting more women in decision-making roles on the teams that organize symposia could offer a simple, effective step forward.

7 Jan 2014

Horizon, AstraZeneca partner to explore oncology-relevant genotypes to identify novel drug targets

Horizon Discovery and AstraZeneca have entered into a research, collaboration and license agreement to explore a range of oncology-relevant genotypes with the aim of identifying and validating a number of novel drug targets. This deal is the second collaboration between AstraZeneca and Horizon, and follows the announcement in April 2013 of an oncology discovery program to explore Horizon's first-in-class kinase target program, HD-001.

7 Jan 2014

New ways to treat substance abuse, neurological diseases and mental illnesses

Researchers at the University at Buffalo have found a way to change alcohol drinking behavior in rodents, using the emerging technique of optogenetics, which uses light to stimulate neurons.

7 Jan 2014

Neuroscience News and Research

Heavy drinking associated with faster decline in cognitive function in middle-aged men

Cognigram can detect early signs of MCI and Alzheimer’s disease

Less gray matter in brain not linked to reading disabilities in people with dyslexia

Hepatitis C infection varies widely among different Hispanic groups in the U.S.

Ultrasound can modulate brain activity to heighten sensory perception in humans

At-home paper test can help spot early symptoms of cognitive issues

FDA approves Farxiga tablets to improve glycemic control in adults with type 2 diabetes mellitus

New technology efficiently transfers investigational antibodies from blood via blood-brain barrier

Neurovance announces interim results from phase 2a pilot study of EB-1020 SR in patients with all subtypes of ADHD

Mild electronic stimulation therapy to upper airway during sleep effective in reducing OSA

Montreal researchers identifies two specific key players in growth of GBM

Epilepsy drug taken during pregnancy not linked with development problems for preschoolers

Nociceptin in brain naturally moderates effects of stress

Experts gather to bring mindfulness in youths

IDMC recommends early stopping of Phase 3 study of ibrutinib in treatment of CLL/SLL

Study sheds light on the biological underpinnings of obesity

Hotspots of fuel consumption in adult brain also show key characteristics of developing brain

Study identifies strategy to help women climb the academic ladder

Horizon, AstraZeneca partner to explore oncology-relevant genotypes to identify novel drug targets

New ways to treat substance abuse, neurological diseases and mental illnesses

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