Protein C News and Research

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Acquiring real-time, accurate and reproducible 4D bioinformatics data with PaSER

In this interview, Chris Adams Ph.D., Business Development Director, Global Bioinformatics, Life Science Mass Spectrometry at Bruker Daltonics, Billerica, MA, USA talks to News-Medical Life Sciences about acquiring real-time, accurate and reproducible 4D-proteomics data with PaSER.

From Bruker Daltonics 20 Apr 2022

Investigating the impact of SARS-CoV-2 Omicron spike mutations

Researchers investigated the impact of amino acid substitutions of SARS-CoV-2 Omicron on spike protein function, processing, and neutralization susceptibility.

20 Apr 2022

Polyethylene glycol-specific antibody responses induced by mRNA-1273 COVID-19 vaccine

Researchers determined the impact of COVID-19 vaccines on polyethylene glycol-specific antibody responses.

20 Apr 2022

Study investigates co-metabolism during SARS-CoV-2 infection

In a new study, researchers investigated host-virus co-metabolism during a SARS-CoV-2 infection.

20 Apr 2022

Waning antibody responses in SARS-CoV-2-infected children and adults over time

In a new study, researchers evaluated the duration of antibodies against SARS-CoV-2.

20 Apr 2022

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

In a new study, researchers assessed the impact of the SARS-CoV-2 Omicron variant on infected human cells and organs.

20 Apr 2022

Study demonstrates subset of vaccine-induced HLA-A*24:02-restricted T cells exhibits enhanced reactivity against the Omicron BA.1 variant

Researchers characterized vaccine-induced T cell response specific for spike proteins of several SARS-CoV-2 variants.

20 Apr 2022

Persistent loss of smell after COVID-19 associated with altered olfactory epithelial gene expression

Researchers performed histology of the olfactory epithelium for smell loss measurements in patients with post-acute sequelae of SARS-CoV-2 infection.

20 Apr 2022

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Researchers demonstrated ocular tropism of SARS-CoV-2 through neuronal invasion in transgenic mice with hACE2 expression.

20 Apr 2022

Study reveals a complexity to how the body "regulates the regulators" of the immune system

Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer cells.

20 Apr 2022

Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils - fibrous, ropelike structures formed by closely linked protein molecules - are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

20 Apr 2022

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

This study is led by Xiujun Cai (Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine). Professor Xiujun Cai's research team screened the whole genome of hepatocellular carcinoma cells (HepG2) through CRISPR / cas9 system under sorafenib treatment, and screened the dominant gene in sorafenib resistance.

20 Apr 2022

New deep learning neural network model predicts physical interactions of protein complexes

From the muscle fibers that move us to the enzymes that replicate our DNA, proteins are the molecular machinery that makes life possible.

20 Apr 2022

Researchers uncover a new protective mechanism against non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease (NAFLD), commonly known as fatty liver disease, is a prevalent disease frequently seen in obese people. Having high fat content in the liver is detrimental as it is strongly associated with severe health problems like diabetes, high blood pressure, and liver cancer.

20 Apr 2022

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Alzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities.

19 Apr 2022

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

A little-studied enzyme has been found in high levels in healthy neurons, levels that scientists say decline with age and more dramatically with Alzheimer's, making adjusting the enzyme's level a potential treatment for both.

19 Apr 2022

Newly identified mechanism explains how fine air pollution particles may cause lung cancer

Scientists have identified a mechanism that explains how fine air pollution particles might cause lung cancer, according to a study published today in eLife.

19 Apr 2022

Researchers reveal possible way to treat newborns with rare genetic lung condition

When babies are born with alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV), their skin starts to turn blue from the under-oxygenated blood in their systems.

19 Apr 2022

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Northwestern Medicine investigators have discovered a novel signaling pathway activated by interferons, a group of immune system proteins, that suppresses the anti-tumor response of interferons in patients with a particular type of blood cancer, according to findings published in Nature Communications.

19 Apr 2022

Researchers investigate Zika virus and Dengue virus co-immunity

In a new study, researchers successfully created new strains of the Zika virus and proved that the process of passaging through mice resulted in significantly increased virulence.

19 Apr 2022

Protein C News and Research

Acquiring real-time, accurate and reproducible 4D bioinformatics data with PaSER

Investigating the impact of SARS-CoV-2 Omicron spike mutations

Polyethylene glycol-specific antibody responses induced by mRNA-1273 COVID-19 vaccine

Study investigates co-metabolism during SARS-CoV-2 infection

Waning antibody responses in SARS-CoV-2-infected children and adults over time

Study explores SARS-CoV-2 Omicron variant and infected colon epithelial cells

Study demonstrates subset of vaccine-induced HLA-A*24:02-restricted T cells exhibits enhanced reactivity against the Omicron BA.1 variant

Persistent loss of smell after COVID-19 associated with altered olfactory epithelial gene expression

Study evaluates the ocular tropism and the possible ocular transmission of SARS-CoV-2 in animal models

Study reveals a complexity to how the body "regulates the regulators" of the immune system

Little-known protein found to play a role in common neurodegenerative disorder

Novel targets for treating sorafenib-resistant hepatocellular carcinoma found using CRISPR-Cas9 screening

New deep learning neural network model predicts physical interactions of protein complexes

Researchers uncover a new protective mechanism against non-alcoholic fatty liver disease

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Levels of little-studied enzyme found to decline with age and more dramatically with Alzheimer’s

Newly identified mechanism explains how fine air pollution particles may cause lung cancer

Researchers reveal possible way to treat newborns with rare genetic lung condition

Researchers discover a novel signaling pathway that defines interferon responses in blood cancers

Researchers investigate Zika virus and Dengue virus co-immunity

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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