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MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

The University of Texas MD Anderson Cancer Center and Amgen today announced two multi-year collaboration agreements aimed at accelerating development of a variety of Amgen's early-stage oncology therapies for patients with leukemia, myelodysplastic syndromes, multiple myeloma, small-cell lung cancer, and other non-lung cancers with small-cell histologies.

1 Jun 2018

Scientists report involvement of estrogen hormone receptor in autoimmune diseases

Women are more prone to the development of autoimmune diseases. The female hormone estrogen is likely to affect the immune system.

1 Jun 2018

New guideline for HER2 testing in breast cancer benefits patients and clinicians

Published today, a Focused Update to the American Society of Clinical Oncology/College of American Pathologists guideline for human epidermal growth factor receptor 2 (HER2) testing in breast cancer brings new levels of clarity that will benefit patients and clinical teams alike.

31 May 2018

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common – and deadliest – type of brain tumor.

30 May 2018

Researchers discover key receptor molecule for flu infection

After decades of research, a research team has discovered the key receptor molecule that enhances the infection of the influenza A virus, providing a novel target for anti-flu drug development.

30 May 2018

Early-life seizures prematurely switch on key brain synapses related to autism

Early-life seizures prematurely switch on key synapses in the brain that may contribute to further neurodevelopmental delay in children with autism and other intellectual disabilities, suggests a new study from researchers at Penn Medicine published online in Cell Reports.

29 May 2018

UH biomedical engineer wins NSF Career Award to improve nanoparticle drug delivery

The National Science Foundation has awarded University of Houston biomedical engineer Sheereen Majd the Career Award and $500,000 to improve nanoparticle drug delivery.

29 May 2018

Single spinal injection reverses chemotherapy-induced pain for months in mice

Researchers at University of California San Diego School of Medicine have found a new way to block a root cause of pain. The key is a naturally occurring protein called apolipoprotein A-I binding protein (AIBP). AIBP binds to toll-like receptor 4 (TLR4), a protein that sits on the surface of cells like an antenna, searching for signs of infection or tissue damage.

29 May 2018

Olfactory receptor in human bladder might prove useful for bladder cancer therapy, diagnosis

Researchers from Bochum have detected an olfactory receptor in the human bladder that might prove useful for bladder cancer therapy and diagnosis.

29 May 2018

Researchers seek new approaches to better protect the eye from glaucoma

Under the increased pressure of glaucoma, scientists want to help the neurons in our eyes better protect themselves and get better help from their friends.

29 May 2018

Researchers identify novel target for bladder cancer

Researchers have identified an olfactory receptor in the human bladder that could prove useful in the diagnosis and treatment of bladder cancer.

29 May 2018

Genome dark matter provides clues to fighting prostate cancer

Through studying the dark matter of the human genome, a team from the University of Michigan has shed light on how the hormone androgen drives prostate cancer and suggested a potential target for future therapy.

28 May 2018

Fewer women meet eligibility criteria for clinical trial of heart failure drugs, study finds

Clinical trial enrolment favors men, according to a study presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress. The study found that fewer women meet eligibility criteria for trials of heart failure medication.

28 May 2018

Young cancer survivors have higher risk of pregnancy associated heart failure, shows study

Girls who survive cancer have a higher risk of developing a deadly heart disease when pregnant later in life, according to a study presented today at Heart Failure 2018 and the World Congress on Acute Heart Failure, a European Society of Cardiology congress.

28 May 2018

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

Anyone who's taken a bite of a sandwich with too much spicy mustard or a piece of sushi with too much wasabi can attest to the tear-inducing sensation these condiments can cause. These loud warnings to the nervous system of exposure to potentially harmful chemicals are triggered by TRPA1, a calcium channel protein sometimes referred to as the "wasabi receptor."

25 May 2018

SLU researcher aims to find solutions for diabetes patients at risk of hypoglycemia

A $150,000 grant from The Leona M. and Harry B. Helmsley Charitable Trust will support research at Saint Louis University led by scientist Gina Yosten, Ph.D. Yosten's team is pursuing solutions for people with diabetes who are at risk of life-threatening drops in blood sugar known as hypoglycemia.

25 May 2018

Study reveals new protective mechanism for tumor cells in breast cancer

Greater knowledge of the mechanisms that contribute to the survival of tumor cells is key to vanquishing them.

25 May 2018

Immune cells promote lung cancer metastases by forming clots in tumors, study finds

University of North Carolina Lineberger Comprehensive Cancer Center researchers have found that by helping to form clots within tumors, immune cells that flock to a particular type of lung cancer are actually building a foundation for the tumor to spread within the body.

25 May 2018

Two genes play vital roles in malignant brain cancer

Two genes play important roles for the formation of malignant cancer in the brain. One gene prevents the formation of the tumor, while another gene promotes the tumor. This is shown in a new dissertation at Umeå University, Sweden.

24 May 2018

NIH commences first-in-human trial evaluating experimental treatment for Ebola

A first-in-human trial evaluating an experimental treatment for Ebola virus disease has begun at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland.

24 May 2018

Receptor News and Research

MD Anderson and Amgen collaborate to accelerate early-stage oncology therapies

Scientists report involvement of estrogen hormone receptor in autoimmune diseases

New guideline for HER2 testing in breast cancer benefits patients and clinicians

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

Researchers discover key receptor molecule for flu infection

Early-life seizures prematurely switch on key brain synapses related to autism

UH biomedical engineer wins NSF Career Award to improve nanoparticle drug delivery

Single spinal injection reverses chemotherapy-induced pain for months in mice

Olfactory receptor in human bladder might prove useful for bladder cancer therapy, diagnosis

Researchers seek new approaches to better protect the eye from glaucoma

Researchers identify novel target for bladder cancer

Genome dark matter provides clues to fighting prostate cancer

Fewer women meet eligibility criteria for clinical trial of heart failure drugs, study finds

Young cancer survivors have higher risk of pregnancy associated heart failure, shows study

Cancer cells co-opt pain-sensing 'neural channel' to increase tolerance against oxidative stress

SLU researcher aims to find solutions for diabetes patients at risk of hypoglycemia

Study reveals new protective mechanism for tumor cells in breast cancer

Immune cells promote lung cancer metastases by forming clots in tumors, study finds

Two genes play vital roles in malignant brain cancer

NIH commences first-in-human trial evaluating experimental treatment for Ebola

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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