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New genetic discovery could lead to better treatment for X-linked diseases

Think back to middle school biology class, when you learned that boys have an X and a Y chromosome inside each cell, and girls have two X's.

20 Oct 2015

Researchers associate neuroimaging data with reading deficits in patients with left-sided stroke

Researchers at Kessler Foundation and Rutgers University correlated neuroimaging data with reading deficits in patients with subacute left hemispheric stroke. Their findings add to our knowledge of the neural mechanisms of reading and may be useful in the development of reading interventions that address specific neurological deficits.

19 Oct 2015

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

Investigators at Brigham and Women's Hospital and the Harvard Stem Cell Institute have established a highly efficient method for making kidney structures from stem cells that are derived from skin taken from patients.

19 Oct 2015

Digital health app facilitates early detection, treatment of COPD exacerbation symptoms

A digital health application for reporting symptoms of Chronic Obstructive Pulmonary Disease (COPD) facilitated early detection and treatment of COPD exacerbation symptoms, according to an analysis from the Temple Lung Center published by Telemedicine and eHealth.

19 Oct 2015

New research shows nicotine increases codeine-induced analgesia

According to new research in rat models, nicotine use over time increases the speed that codeine is converted into morphine within the brain, by increasing the amount of a specific enzyme. It appears smokers' brains are being primed for a bigger buzz from this common pain killer - which could put them at a higher risk for addiction, and possibly even overdose.

19 Oct 2015

University of Maryland develops GammaPod system to treat early-stage breast cancer

After more than a decade of research and development, researchers in the Department of Radiation Oncology at the University of Maryland School of Medicine will begin enrolling patients in the first clinical trial of GammaPod, a new high-precision, image-guided radiation therapy system specifically designed to treat early-stage breast cancer.

19 Oct 2015

BET protein family plays key role in regulation of normal neuronal development and function

Regulation of a family of brain proteins known as bromodomain and extra-terminal domain containing transcription regulators (BETs) plays a key role in normal cognition and behavior, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published advanced online on September 21 and in print October 19 in The Journal of Experimental Medicine.

19 Oct 2015

New research raises hope for novel cancer immunotherapy

New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.

16 Oct 2015

Brown University researchers describe new method to test HIV mutations

Tests that can distinguish whether HIV-positive people are infected with a drug-resistant strain or a non-resistant strain allow patients to get the most effective treatment as quickly as possible. In the November edition of the Journal of Molecular Diagnostics, a team of Brown University researchers describes a new method that works faster and more sensitively in lab testing than the current standard technologies.

16 Oct 2015

UM SOM researchers to initiate first clinical trial of GammaPod system in patients with early-stage breast cancer

16 Oct 2015

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

A Washington State University researcher has received a $2.6 million federal grant to study the body's ability to keep tobacco smoke components from causing cancer.

16 Oct 2015

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

Johannes Reiter, former PhD student in the group of Krishnendu Chatterjee at the Institute of Science and Technology Austria (IST Austria), is co-author of a Nature paper on genetic alterations that drive the progression and relapse of cancer.

16 Oct 2015

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Using two complementary analytical approaches, scientists at Whitehead Institute and Broad Institute of MIT and Harvard have for the first time identified the universe of genes in the human genome essential for the survival and proliferation of human cell lines or cultured human cells.

16 Oct 2015

Safe, effective douche-based rectal microbicide can prevent HIV in gay men

Enemas are commonly used by men who have sex with men (MSM) and transwomen (TW) before sexual intercourse. But these groups are vulnerable to HIV and a host of other sexually transmitted infections because enemas -- even those that use tap water -- can seriously damage the thin tissue lining the rectum, allowing for easier transmission of harmful viruses and bacteria.

16 Oct 2015

Study finds link between microbial signatures and triple negative breast cancer

Cancer is a result of normal cellular functions going wildly awry on a genetic level. That fact has been known for some time, but increasing evidence is showing that the human microbiome, the diverse population of microorganisms within every person, may play a key role in either setting the stage for cancer or even directly causing some forms of it.

16 Oct 2015

People who experience weight discrimination more likely to develop chronic health problems

In recent years, Florida State University College of Medicine researchers Angelina R. Sutin and Antonio Terracciano have found that people who experience weight discrimination are more likely to become or remain obese, to develop chronic health problems and to have a lower satisfaction with life.

16 Oct 2015

EKF’s PointMan™ used in cancer biopsy research

EKF, announces results from a study involving EKF Molecular’s PointMan™ DNA enrichment technology have been published in Clinical Cancer Research.

From EKF Diagnostics 15 Oct 2015

New method uses advanced noninvasive neuroimaging to localize and identify epileptic lesions

Epilepsy affects more than 65 million people worldwide. One-third of these patients have seizures that are not controlled by medications. In addition, one-third have brain lesions, the hallmark of the disease, which cannot be located by conventional imaging methods.

15 Oct 2015

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

Kessler researchers assessed moderate to severe traumatic brain injury (TBI) for frontal behavioral syndromes and cognitive function. Their finding suggest that adding the Frontal Systems Behavior Scale to neuropsychological assessment may yield useful information about the behavioral sequelae of TBI.

15 Oct 2015

UTHealth biochemists expose structures of IP3R calcium channels

Calcium is a crucial element in the body that controls thought, movement and other bodily functions. These events are directed by specialized proteins called ion channels that allow the flow of calcium ions in and out of cells and among cell compartments. For years, scientists have been unsure how calcium ion channels function.

15 Oct 2015

Medical School News and Research

New genetic discovery could lead to better treatment for X-linked diseases

Researchers associate neuroimaging data with reading deficits in patients with left-sided stroke

BWH, HSCI establish new method for making kidney structures from stem cells derived from patients

Digital health app facilitates early detection, treatment of COPD exacerbation symptoms

New research shows nicotine increases codeine-induced analgesia

University of Maryland develops GammaPod system to treat early-stage breast cancer

BET protein family plays key role in regulation of normal neuronal development and function

New research raises hope for novel cancer immunotherapy

Brown University researchers describe new method to test HIV mutations

UM SOM researchers to initiate first clinical trial of GammaPod system in patients with early-stage breast cancer

WSU scientist wins federal grant to explore metabolism pathways, tobacco carcinogens

Analysis of high-throughput sequencing data reveals new genes linked to chronic lymphocytic leukemia

Set of genes identified in human genome essential for survival, proliferation of human cell lines

Safe, effective douche-based rectal microbicide can prevent HIV in gay men

Study finds link between microbial signatures and triple negative breast cancer

People who experience weight discrimination more likely to develop chronic health problems

EKF’s PointMan™ used in cancer biopsy research

New method uses advanced noninvasive neuroimaging to localize and identify epileptic lesions

Developing tailored interventions for cognitive and behavioral symptoms key to improving outcomes after TBI

UTHealth biochemists expose structures of IP3R calcium channels

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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