Brain Cell News and Research

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Professor utilizes $300,000 N.Y. grant to study adult neural stem cells

Rensselaer Polytechnic Institute Assistant Professor of Biomedical Engineering Deanna Thompson is utilizing more than $300,000 in New York state funding as part of the state stem cell research program, NYSTEM, to study adult neural stem cells.

10 Mar 2011

New study sheds 'light' on intricate brain cell connections responsible for anxiety

A new study sheds light--both literally and figuratively--on the intricate brain cell connections responsible for anxiety.

10 Mar 2011

Parkinson's disease medication turns on critical gene, protects brain cells

In a major breakthrough in the battle against Parkinson's disease, researchers at the University of Colorado School of Medicine have discovered a drug that stops the progression of the degenerative illness in mice and is now being tested in humans.

9 Mar 2011

Therapeutic potential of iPS cells may be limited by reprogramming errors and genomic instability

In the past few months, a slew of papers have indicated that the therapeutic potential of a promising type of stem cell, called induced pluripotent stem (iPS) cells, might be limited by reprogramming errors and genomic instability. iPS cells are engineered by reprogramming fully differentiated adult cells, often skin cells, back to a primitive, embryonic-like state.

9 Mar 2011

Unique gene therapy to combat Parkinson's disease

Physicians at Rush University Medical Center are testing a unique gene therapy product called CERE-120 to evaluate if its use can improve the symptoms of Parkinson's disease. Rush is one of 11 sites in the U.S. and the only site in Illinois enrolling patients into the new, double-blinded trial.

9 Mar 2011

hUCBs and MenSCs transplant may offer future therapeutic benefit for AD, stroke, ALS

Transplanting stem cells derived from umbilical cord blood cells and menstrual blood cells may offer future therapeutic benefit for those suffering from stroke, Alzheimer's disease, and amyotrophic lateral sclerosis, says a team of neuroscience researchers from the University of South Florida's Department of Neurosurgery and Brain Repair and collaborators from three private-sector research groups, Saneron CCEL Therapeutics, Inc., Tampa, FL, Cryo-Cell International, Inc., Oldsmar, FL, and Cryopraxis, Cell Praxis, BioRio, Rio de Janeiro, Brazil.

8 Mar 2011

New study unmasks molecule that can protect against epileptic seizure

For years brain scientists have puzzled over the shadowy role played by the molecule putrescine, which always seems to be present in the brain following an epileptic seizure, but without a clear indication whether it was there to exacerbate brain damage that follows a seizure or protect the brain from it. A new Brown University study unmasks the molecule as squarely on the side of good: It seems to protect against seizures hours later.

6 Mar 2011

Novel gene therapy can promote removal of amyloid plaques and prevent Alzheimer's disease

Gene therapy that boosts the ability of brain cells to gobble up toxic proteins prevents development of Alzheimer's disease in mice that are predestined to develop it, report researchers at Georgetown University Medical Center. They say the treatment - which is given just once - could potentially do the same in people at the beginning stages of the disease.

5 Mar 2011

Brain enzyme can restore even old, fading memories, say researchers

Even long after it is formed, a memory in rats can be enhanced or erased by increasing or decreasing the activity of a brain enzyme, say researchers supported, in part, by the National Institutes of Health.

4 Mar 2011

Lactate plays critical role in formation of long-term memory

Researchers from Mount Sinai School of Medicine have found that lactate, a type of energy fuel in the brain, plays a critical role in the formation of long-term memory. These findings have important implications for common illnesses like Alzheimer's disease, other neurodegenerative disorders, aging-related memory impairment and diabetes. The research is published in the March 4th issue of the journal Cell.

4 Mar 2011

Baby frozen to correct brain damage at birth makes full recovery

Baby Ella was born starved of oxygen but doctors cooled her body for three days to reduce brain damage. She made a complete recovery. After birth Ella was wrapped in a special blanket filled with fluid which cooled her whole body down from the normal 37°c to 33.5°c by doctors at Addenbrooke’s Hospital in Cambridge.

3 Mar 2011

Study demonstrates neuronal loss during initial stages of HIV infection in mouse model

A new mouse model closely resembles how the human body reacts to early HIV infection and is shedding light on nerve cell damage related to the disease, according to researchers funded by the National Institutes of Health.

3 Mar 2011

Experimental drug may help preserve neurological function in survivors of sudden cardiac arrest

An experimental drug that targets a brain system that controls inflammation might help preserve neurological function in people who survive sudden cardiac arrest, new research suggests.

2 Mar 2011

Bone marrow stem cell transplantation feasible, safe treatment for children with severe traumatic brain injury

For children with severe traumatic brain injury (TBI), transplantation of stem cells derived from the patients' own bone marrow is a "logistically feasible and safe" treatment procedure, reports the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

2 Mar 2011

New study: Immune molecules can regulate synaptic connections in brain

The number of connections between nerve cells in the brain can be regulated by an immune system molecule, according to a new study from UC Davis. The research, published Feb. 27 in the journal Nature Neuroscience, reveals a potential link between immunity, infectious disease and conditions such as schizophrenia or autism.

27 Feb 2011

PACAP hormone levels linked to post-traumatic stress disorder

High blood levels of a hormone produced in response to stress are linked to post-traumatic stress disorder in women but not men, a study from researchers at Emory University and the University of Vermont has found.

25 Feb 2011

Aminothiazoles as therapeutic leads for prion diseases

Scientists who examined more than 10,000 chemical compounds during the last year in search of potential new drugs for a group of untreatable brain diseases, are reporting that one substance shows unusual promise.

24 Feb 2011

Brain reward center responds to good and bad experiences

The so-called reward center of the brain may need a new name, say scientists who have shown it responds to good and bad experiences. The finding, published in PLoS One, may help explain the "thrill" of thrill-seeking behavior or maybe just the thrill of surviving it, according to scientists at Georgia Health Sciences University and East China Normal University.

23 Feb 2011

Research: MEF2D protein in mitochondria appears to contribute early steps in Parkinson's disease

For the last several years, neurologists have been probing a connection between Parkinson's disease and problems with mitochondria, the miniature power plants of the cell.

15 Feb 2011

Measurements of hand movement control may help determine severity of ADHD in children

Measurements of hand movement control may help determine the severity of attention deficit hyperactivity disorder in children, according to joint studies published in the February 15, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

15 Feb 2011

Brain Cell News and Research

Professor utilizes $300,000 N.Y. grant to study adult neural stem cells

New study sheds 'light' on intricate brain cell connections responsible for anxiety

Parkinson's disease medication turns on critical gene, protects brain cells

Therapeutic potential of iPS cells may be limited by reprogramming errors and genomic instability

Unique gene therapy to combat Parkinson's disease

hUCBs and MenSCs transplant may offer future therapeutic benefit for AD, stroke, ALS

New study unmasks molecule that can protect against epileptic seizure

Novel gene therapy can promote removal of amyloid plaques and prevent Alzheimer's disease

Brain enzyme can restore even old, fading memories, say researchers

Lactate plays critical role in formation of long-term memory

Baby frozen to correct brain damage at birth makes full recovery

Study demonstrates neuronal loss during initial stages of HIV infection in mouse model

Experimental drug may help preserve neurological function in survivors of sudden cardiac arrest

Bone marrow stem cell transplantation feasible, safe treatment for children with severe traumatic brain injury

New study: Immune molecules can regulate synaptic connections in brain

PACAP hormone levels linked to post-traumatic stress disorder

Aminothiazoles as therapeutic leads for prion diseases

Brain reward center responds to good and bad experiences

Research: MEF2D protein in mitochondria appears to contribute early steps in Parkinson's disease

Measurements of hand movement control may help determine severity of ADHD in children

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