Cell Production News and Research

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Scientists identify compounds for stem-cell production from adult cells

In the study, the scientists screened known drugs and identified small molecules that could replace conventional reprogramming genes, which can have dangerous side effects.

6 Nov 2008

Wide variability in rheumatoid arthritis drug Methotrexate suggests alternative dosing should be considered

Methotrexate (MTX) is commonly used to treat rheumatoid arthritis (RA) and is suggested as the "anchor" drug in treating the disease.

5 Nov 2008

Good genes behaving badly behind type 1 diabetes

Investigators combing the genome in the hope of finding genetic variants responsible for triggering early-onset diabetes may be looking in the wrong place, new research at the Stanford University School of Medicine suggests.

31 Oct 2008

One dose chemo treatment the best for testicular cancer

New research from the UK has found that one dose of chemotherapy is the best way to cure testicular cancer in many patients.

6 Oct 2008

Discovery of important fat precursor cell

To understand where fat comes from, you have to start with a skinny mouse. By using such a creature, and observing the growth of fat after injections of different kinds of immature cells, Rockefeller University scientists have discovered an important fat precursor cell that may in time explain how changes in the numbers of fat cells might increase and lead to obesity.

5 Oct 2008

Pain is not a symptom of arthritis, pain causes arthritis

Pain is more than a symptom of osteoarthritis, it is an inherent and damaging part of the disease itself, according to a study published today in journal Arthritis and Rheumatism.

29 Sep 2008

Researchers devise means to create blood by discovering earliest form of human blood stem cells

Johns Hopkins researchers have discovered the earliest form of human blood stem cells and deciphered the mechanism by which these embryonic stem cells replicate and grow. They also found a surprising biological marker that pinpoints these stem cells, which serve as the progenitors for red blood cells and lymphocytes.

28 Aug 2008

Transformation of ordinary cells into insulin-makers improves symptoms of diabetes

Scientists in the U.S. have successfully transformed ordinary cells into insulin-producing cells in a living mouse and thereby improved the symptoms of diabetes.

28 Aug 2008

Psychological stress and how it might affect allergy sufferers

A new study here shows that even slight stress and anxiety can substantially worsen a person's allergic reaction to some routine allergens.

14 Aug 2008

Findings may aid in bone marrow transplants, blood diseases

New research sheds light on the biological events by which stem cells in the bone marrow develop into the broad variety of cells that circulate in the blood. The findings may help improve the success of bone marrow transplants and develop better treatments for life-threatening blood diseases.

5 Aug 2008

Standards in stem cell research

Standards in stem cell research help both scientists and regulators to manage uncertainty and the unknown, according to new research funded by the Economic and Social Research Council. Efforts to standardise practices across different labs is, however, a balancing act where the autonomy of scientists and fragility of living material need to be weighed against the need for comparable data.

17 Jul 2008

Virus injection could offer long term relief for Parkinson's

Gene therapy could offer a new, long-lasting way to treat Parkinson's disease, research results announced Tuesday 15 July at FENS 2008 suggest. Dr Deniz Kirik of the University of Lund in Sweden has been using viruses to insert a new combination of genes into animals' brains, where they help produce the dopamine that is lacking in Parkinson's disease. The results suggest the treatment is very effective in animal models for several months, possibly years.

15 Jul 2008

Insulin suppresses receptors that cause cascade of inflammation

Researchers at the University at Buffalo -- the first to identify the anti-inflammatory and cardioprotective properties of insulin -- now have discovered one pathway through which the hormone produces this effect.

13 Jul 2008

GILZ protein may have big role in making more bone and less fat

A small protein may have a big role in helping you make more bone and less fat, researchers say. "The pathways are parallel, and the idea is if you can somehow disrupt the fat production pathway, you will get more bone," says Dr. Xingming Shi, bone biologist at the Medical College of Georgia Institute of Molecular Medicine and Genetics.

1 Jul 2008

Drug combo offers new approach for reversing type 1 diabetes

Promising results from a study that tested a new approach for reversing Type 1 diabetes are being presented this week at the American Diabetes Association's 68th Annual Scientific Session in San Francisco.

11 Jun 2008

Human stem cells show promise against fatal children's diseases

Scientists have used human stem cells to dramatically improve the condition of mice with a neurological condition similar to a set of diseases in children that are invariably fatal, according to an article in the June issue of the journal Cell Stem Cell.

4 Jun 2008

New approach to treating autoimmune disease offered by Weizmann scientists

In autoimmune diseases, the immune system turns against the body's own tissues and organs, wreaking havoc and destruction for no apparent reason. Partly because the origins of these diseases are so obscure, no effective treatment exists, and the suffering they inflict is enormous.

2 Jun 2008

New multi-million pound study to find the cause of Type 1 diabetes

Juvenile Diabetes Research Foundation (JDRF) has awarded more than £3 million to fund a research centre that will investigate the causes of Type 1 diabetes - a condition that results from an immune attack on the body's insulin producing cells. The study, known as the JDRF Centre for Diabetes Genes, Autoimmunity and Prevention (D-GAP), aims to understand how and why Type 1 diabetes occurs, knowledge that may help develop future therapies with the aim of preventing the condition.

28 May 2008

NIAID to advance B-cell approach to HIV vaccines

To advance underdeveloped approaches to designing a preventive HIV vaccine, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, is launching a new program to foster the study of B cells, immune cells that can produce antibodies with the capacity to neutralize HIV.

20 May 2008

Researchers step closer to finding ways to treat type 1 diabetes

Scientists at Washington University School of Medicine in St. Louis working with diabetic mice have examined in unprecedented detail the immune cells long thought to be responsible for type 1 diabetes.

9 May 2008