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New and improved solid phase ChIP assay kit for FFPE tissues introduced by Chromatrap

Chromatrap® has introduced a new and improved version of it’s popular solid phase chromatin immunoprecipitation (ChIP) assay kit for chromatin extracted from Formalin Fixed Paraffin Embedded (FFPE) tissue.

From Chromatrap® - Porvair Sciences Ltd 4 May 2017

Lethal DNA re-replication may be used to attack cancer cells

DNA over-replication is a phenomenon that can have devastating consequences for proliferating cells. When parts of the genome are duplicated more than once, cells suffer from 'genomic instability' (alterations to the structure, composition and/or number of chromosomes), and this process gives rise to aberrant cells as those detected in many carcinomas.

4 May 2017

Phagocytosis educates the immune system

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation.

4 May 2017

New research uncovers role of mysterious molecule in skin cancer

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) at Lake Nona uncovers the modus operandi of a mysterious molecule called SPRIGHTLY that has been previously implicated in colorectal cancer, breast cancer, and melanoma.

3 May 2017

Detailed images reveal how regulatory proteins affect function of brain receptors

Scientists at Columbia University have obtained the first detailed images of interactions between the AMPA receptor and molecules that regulate chemical signaling in the brain.

3 May 2017

IDIBELL researchers reveal role of endoplasmic reticulum in cell death process due to starvation

Researchers from the Cell death group of the Bellvitge Biomedical Research Institute, led by Dr. Cristina Muñoz-Pinedo, have characterized the cell death process due to starvation, in which the endoplasmic reticulum plays a leading role.

3 May 2017

New treatment offers hope for kidney failure and transplant patients with rare disorder

A novel treatment offers kidney failure and kidney transplant patients with a rare disorder new hope. The treatment allows targeted elimination of plasma cell clones producing abnormal proteins that deposits in the kidneys and leads to kidney failure, according to new research.

3 May 2017

miniDAWN TREOS II SEC-MALS Detector for Essential Protein and Polymer Characterization

Wyatt Technology, the world leader in instrumentation for absolute macromolecular and nanoparticle characterization, announces the launch of its next generation multi-angle light scattering (MALS) detector for SEC/GPC, the miniDAWN® TREOS® II. The TREOS II is the only SEC-MALS detector for size exclusion or gel permeation chromatography that offers full field serviceability, extended ease-of-use, and a built-in upgrade path from HPLC to UHPLC technology.

From Waters | Wyatt Technology 3 May 2017

Phthalate exposure linked to increased risk of allergies among children

Phthalates, which are used as plasticizers in plastics, can considerably increase the risk of allergies among children.

3 May 2017

Moderate cardiorespiratory fitness can protect from fatty liver

According to a new Finnish study, cardiorespiratory fitness is inversely related to risk of fatty liver. The research was conducted at the University of Turku, Finland, and shows that, despite the person's weight, achieving moderate cardiorespiratory fitness can protect from fatty liver.

3 May 2017

Study reveals gluten diet is not connected with heart disease among non-celiac people

The study findings published online in the British Medical Journal today reveal that the intake of a long-term gluten diet is not connected with coronary heart disease among people without celiac disease.

3 May 2017

Impaired effects of insulin can increase cancer risk, shows study

Over the decades, scientists have repeatedly shown that patients with increased levels of the hormone insulin in their blood can experience increased risks of cancer. Surprisingly, however, Joslin Diabetes Center researchers now have discovered that impaired effects of insulin also can boost these risks.

3 May 2017

EKF Diagnostics expands the distribution of its Procalcitonin LiquiColor® Test into Eastern Europe, Middle East and APAC regions

EKF, announces that it is expanding the distribution of its Procalcitonin LiquiColor Test into Eastern Europe, Middle East and APAC regions.

From EKF Diagnostics 3 May 2017

Researchers show how Epstein-Barr virus manages to persist inside immune system's B cells

Viruses are notorious for taking over their host's operations and using them to their own advantage. But few human viruses make themselves quite as cozy as the Epstein-Barr virus, which can be found in an estimated nine out of ten humans without causing any ill effects.

3 May 2017

Researchers identify key player in initiation and progression of melanoma

Identification and functional validation of proteins involved in tumorigenesis are essential steps toward advancing cancer precision medicine. In The Journal of Clinical Investigation researchers from VIB, KU Leuven together with colleagues from INSERM now report the important role for FES in the initiation and progression of melanoma, a malignant type of skin cancer, that is notoriously quick to metastasize and that responds poorly to existing cancer treatments.

3 May 2017

Study suggests how existing and emerging immunotherapy treatments could be successful for sarcomas

Sarcomas- cancers of the connective tissues like muscles, joints, fat and bone - come in dozens of subtypes. Clinical trial results have been mixed when treating these diverse tumors with immunotherapy, a targeted therapeutic strategy that has success in other cancers.

3 May 2017

Study finds no link between gluten intake and heart disease risk in people without celiac disease

A study of more than 100,000 men and women revealed that dietary gluten is not associated with heart disease risk in people without celiac disease. The findings also suggest that limiting whole grains as part of a low-gluten diet may increase the risk of heart disease in people who do not have celiac disease.

3 May 2017

TSRI study reveals clues to where tumor metastases are born

Scientists at The Scripps Research Institute have discovered why some cancers may reoccur after years in remission.

3 May 2017

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Myriad Genetics, Inc. and Clovis Oncology, Inc. have announced a companion diagnostic collaboration to support a post-marketing regulatory commitment related to Clovis’ PARP inhibitor, Rubraca. Financial terms of the deal were not disclosed.

3 May 2017

Researchers uncover new mechanism that explains cause of portal hypertension

Investigators at the Medical University of South Carolina have identified a critical regulatory mechanism for the production of nitric oxide. Endothelial nitric oxide synthase is the enzyme responsible for the production of NO and its activity is tightly controlled in liver endothelial cells via a series of complex molecular mechanisms; however, in liver injury, eNOS activity, and subsequently NO production, is dysregulated.

3 May 2017

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G Protein News and Research

New and improved solid phase ChIP assay kit for FFPE tissues introduced by Chromatrap

Lethal DNA re-replication may be used to attack cancer cells

Phagocytosis educates the immune system

New research uncovers role of mysterious molecule in skin cancer

Detailed images reveal how regulatory proteins affect function of brain receptors

IDIBELL researchers reveal role of endoplasmic reticulum in cell death process due to starvation

New treatment offers hope for kidney failure and transplant patients with rare disorder

miniDAWN TREOS II SEC-MALS Detector for Essential Protein and Polymer Characterization

Phthalate exposure linked to increased risk of allergies among children

Moderate cardiorespiratory fitness can protect from fatty liver

Study reveals gluten diet is not connected with heart disease among non-celiac people

Impaired effects of insulin can increase cancer risk, shows study

EKF Diagnostics expands the distribution of its Procalcitonin LiquiColor® Test into Eastern Europe, Middle East and APAC regions

Researchers show how Epstein-Barr virus manages to persist inside immune system's B cells

Researchers identify key player in initiation and progression of melanoma

Study suggests how existing and emerging immunotherapy treatments could be successful for sarcomas

Study finds no link between gluten intake and heart disease risk in people without celiac disease

TSRI study reveals clues to where tumor metastases are born

Myriad and Clovis ink deal on FDA-approved BRACAnalysis CDx test to identify patients with germline BRCA mutations for rucaparib treatment

Researchers uncover new mechanism that explains cause of portal hypertension

Industry Focus eBook - Cell biology (5th edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

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