Genetic Engineering News and Research

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A new function identified for glycine receptors during embryonic development

Glycine receptors are one of the most widely distributed inhibitory receptors in the central nervous system and have important roles in a variety of physiological processes.

18 Dec 2019

Moffitt researchers develop efficient method for creating mouse models to study melanoma

Genetically engineered mouse models are often used by scientists to study how the addition, deletion or mutation of genes affects the development of disease and effects of drugs.

17 Dec 2019

The sympathetic nervous system can modulate action of defense cells in autoimmune disease

The results of a study conducted in Brazil suggest that the sympathetic nervous system - the part of the autonomous nervous system that controls responses to danger or stress - can modulate the action of defense cells in patients with autoimmune diseases.

16 Dec 2019

Tackling antibiotic resistance head-on with CRISPR

With modern advances in genetic engineering occurring almost every day, the latest discovery concerns antibiotic resistance. Using the powerful gene editor CRISPR, scientists reported the development of a gene-drive system that is 100 times as efficient as other current systems at inactivating a specific bacterial gene responsible for making the bacterium antibiotic-resistant and which is present as multiple copies within the same bacterial cell.

16 Dec 2019

Novel HIV vaccine shows promise

There are millions living with HIV and researchers have been working towards making a successful vaccine against the deadly infection for the past 35 years with no success. Now a new blueprint is being developed to prevent the infection.

15 Dec 2019

Horizon Discovery adds predesigned synthetic single guide RNA to its product range

Horizon Discovery Group plc, a global leader in the application of gene editing and gene modulation technologies, today announced the addition of predesigned synthetic single guide RNA (sgRNA) to its product range.

From Revvity 13 Dec 2019

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

Researchers have vaccinated mice against the Zika virus, whilst others have discovered a new platform for flavivirus vaccines.

12 Dec 2019

ERC promotes CRISPR research to better treat infections

Chase Beisel heads the "Synthetic Biology of RNA" research group at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg, a branch of the Helmholtz Centre for Infection Research in Braunschweig and run in collaboration with the Julius-Maximilians-Universität in Würzburg.

10 Dec 2019

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury.

9 Dec 2019

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Bacteria and the viruses that infect them are engaged in a molecular arms race as ancient as life itself. Evolution has equipped bacteria with an arsenal of immune enzymes, including CRISPR-Cas systems, that target and destroy viral DNA. But bacteria-killing viruses, also known as phages, have devised their own tools to help them outmaneuver even the most formidable of these bacterial defenses.

9 Dec 2019

Novel tool for assessing children's overall addiction to digital devices

A new study developed and validated a tool for assessing children's overall addiction to digital devices. The study, which found that more than 12% of children ages 9-12 years were at risk of addiction to digital devices for uses including video gaming, social media, and texting, is published in Cyberpsychology, Behavior, and Social Networking, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

9 Dec 2019

The role of adenosine in neurodegeneration and brain regeneration

The role of adenosine in neurodegeneration and neuroregeneration has led to growing attention on adenosine receptors as potential drug targets in a range of brain disorders, including neuroregenerative therapy and treatment for amyotrophyic lateral sclerosis.

8 Dec 2019

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a new study in the Nature journal Communications Biology describes a new innovation that could accelerate this work by rapidly revealing unintended and potentially harmful changes introduced by a gene editing process.

6 Dec 2019

Genetically engineered living hydrogel material facilitates intestinal wound healing

About 1.6 million people in the US alone currently have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 70,000 new cases are diagnosed in the USA each year.

6 Dec 2019

New approach can improve the activity of CAR-T cells against blood and solid cancers

A new approach to programing cancer-fighting immune cells called CAR-T cells can prolong their activity and increase their effectiveness against human cancer cells grown in the laboratory and in mice, according to a study by researchers at the Stanford University School of Medicine.

5 Dec 2019

LSTM researchers genetically modified malaria carrying mosquitoes

Researchers at LSTM have genetically modified malaria carrying mosquitoes in order to demonstrate the role of particular genes in conferring insecticide resistance.

5 Dec 2019

New model can help study the mechanisms of bone metastasis, tumor immune response

The Research Team reports the establishment of B6Ca P, an allograft tumor line from a Hi-Myc transgenic mouse that had been backcrossed onto C57BL/6J background.

4 Dec 2019

Study shows intestinal involvement in the development and progression of MS

It is incompletely understood which factors in patients with multiple sclerosis (MS) act as a trigger for the immune system to attack the brain and spinal cord.

4 Dec 2019

Study explores whether disability is a risk factor for miscarriage

A new study compared the proportion of women with any cognitive, physical, or independent living disability who experienced a miscarriage during the previous 5-year period to women without disabilities.

3 Dec 2019

Study: Complementary health approach is recommended by over half of U.S. office-based physicians

A new study has shown that more than half (53.1%) of office-based physicians in the U.S., across specialty areas, recommended at least one complementary health approach (CHA) to their patients during the previous 12 months, with female physicians (63.2%) more likely to recommend a CHA than male physicians (49.3%).

3 Dec 2019

Genetic Engineering News and Research

A new function identified for glycine receptors during embryonic development

Moffitt researchers develop efficient method for creating mouse models to study melanoma

The sympathetic nervous system can modulate action of defense cells in autoimmune disease

Tackling antibiotic resistance head-on with CRISPR

Novel HIV vaccine shows promise

Horizon Discovery adds predesigned synthetic single guide RNA to its product range

Developments in the search for a Zika vaccine - success in mice and a new platform for flavivirus vaccines

ERC promotes CRISPR research to better treat infections

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Some phages employ new strategy to avoid becoming the next casualty of DNA-dicing enzymes

Novel tool for assessing children's overall addiction to digital devices

The role of adenosine in neurodegeneration and brain regeneration

New tool can rapidly reveal unintended changes made by CRISPR-directed gene editing

Genetically engineered living hydrogel material facilitates intestinal wound healing

New approach can improve the activity of CAR-T cells against blood and solid cancers

LSTM researchers genetically modified malaria carrying mosquitoes

New model can help study the mechanisms of bone metastasis, tumor immune response

Study shows intestinal involvement in the development and progression of MS

Study explores whether disability is a risk factor for miscarriage

Study: Complementary health approach is recommended by over half of U.S. office-based physicians

eBook: Using iPSCs models for human disease research and drug discovery eBook

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