Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes.

10 Nov 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

Study sheds light on how Gram-negative bacteria construct outer membrane to resemble body armor

A new study published in the journal Science Advances sheds light on how Gram-negative bacteria like E. coli construct their outer membrane to resemble body armor, which has far-reaching implications for the development of antibiotics.

3 Nov 2022

NIH awards $2.1 million grant to UMass Amherst epidemiologist

A University of Massachusetts Amherst epidemiologist has been awarded a five-year, $2.1 million grant from the National Institutes of Health (NIH) to continue research that aims to understand how physical and mental health during pregnancy can help predict cardiovascular and mental health disorders in middle age.

2 Nov 2022

New nanovaccine greatly improves cytokine production

Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer. However, immune checkpoint inhibition therapy is only effective in 20%–30% of cancer patients, so developing better drug delivery systems to induce anticancer cellular immunity is necessary.

1 Nov 2022

Scientists reveal anti-inflammatory molecules that play an important role in aging

Aging involves complicated plot twists and a large cast of characters: inflammation, stress, metabolism changes, and many others. Now, a team of Salk Institute and UC San Diego scientists reveal another factor implicated in the aging process - a class of lipids called SGDGs (3-sulfogalactosyl diacylglycerols) that decline in the brain with age and may have anti-inflammatory effects.

31 Oct 2022

Appel Alzheimer's Disease Research Institute Symposium reveals new developments in dementia research

The 10th annual Appel Alzheimer's Disease Research Institute Symposium brought fascinating reports of progress in understanding Alzheimer's and related neurodegenerative diseases.

28 Oct 2022

Study provides new insights into genetic form of frontotemporal dementia

Dementia encompasses a range of neurodegenerative conditions that lead to memory loss and cognitive deficiencies and affect some 55 million people worldwide.

28 Oct 2022

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University have taken a key step toward improving and lengthening the lives of cystic fibrosis patients, who experience chronically clogged airways and a dramatically shortened life expectancy.

27 Oct 2022

Advanced type of nanoparticle could help fight hard-to-treat cancers

Nanoparticles, or tiny molecules that can deliver a payload of drug treatments and other agents, show great promise for treating cancers.

27 Oct 2022

Discovery points to a new understanding of Stargardt disease progression

Using a new stem-cell-based model made from skin cells, scientists found the first direct evidence that Stargardt-related ABCA4 gene mutations affect a layer of cells in the eye called the retinal pigment epithelium (RPE).

27 Oct 2022

New discovery may change the textbook model of GPCR-mediated signaling

Researchers at University of California San Diego have identified a new signaling process involving G protein-coupled receptors (GPCRs), a cellular target already exploited by hundreds of diverse drugs.

27 Oct 2022

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

A study tested the hypothesis that the ACE-2 receptor of SARS-CoV-2 is not only an attachment factor in viral infection but also plays a role in activating the viral spike protein to facilitate membrane fusion.

27 Oct 2022

Surprising discovery in people of Polynesian ancestry offers clues to genetic underpinnings of high cholesterol

The discovery of a genetic variant that is relatively common among people of Polynesian ancestry, but incredibly rare in most other populations, is giving clues to the genetic underpinnings of high cholesterol in all people, according to new research led by University of Pittsburgh School of Public Health geneticists in partnership with several other groups, including the University of Otago and the Samoan health research community.

21 Oct 2022

Lipids News and Research

Further Reading

Novel branched ionizable lipid greatly increases the efficiency of mRNA delivery

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Study sheds light on how Gram-negative bacteria construct outer membrane to resemble body armor

NIH awards $2.1 million grant to UMass Amherst epidemiologist

New nanovaccine greatly improves cytokine production

Scientists reveal anti-inflammatory molecules that play an important role in aging

Appel Alzheimer's Disease Research Institute Symposium reveals new developments in dementia research

Study provides new insights into genetic form of frontotemporal dementia

OSU researchers take major step toward improving, lengthening the lives of cystic fibrosis patients

Advanced type of nanoparticle could help fight hard-to-treat cancers

Discovery points to a new understanding of Stargardt disease progression

New discovery may change the textbook model of GPCR-mediated signaling

Study finds that ACE-2 is not biochemically required for SARS-CoV2 membrane fusion

Surprising discovery in people of Polynesian ancestry offers clues to genetic underpinnings of high cholesterol

Male mice three times more likely than females to survive E. coli infection

Do hypertension, dyslipidemia, and new-onset diabetes mellitus play a part in post-COVID sequelae?

SARS-CoV-2 envelope structural protein found to form voltage-activated and calcium-activated calcium channels

Rheumatoid arthritis drug can be repurposed to improve diabetes-associated symptoms

Thirdhand smoke exposure elevates biomarkers associated with the initiation of skin diseases

Study opens up new approaches for treating fatty liver disease

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo