Phenotype News and Research

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Leukemia type B cell can transform into a macrophage through epigenetic changes

All the tissues of our body have the same DNA, but they perform very different functions and have very different aspects.

13 Nov 2019

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

An autoimmune attack on uninfected red blood cells likely contributes to anaemia - a shortage of red blood cells - in people with malaria, according to a new study published in eLife.

12 Nov 2019

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Impaired liver function during pregnancy may alter gut bacteria composition and increase the risk of obesity in children, according to results presented at The Society for Endocrinology Annual Conference.

11 Nov 2019

Children with Down syndrome at greater risk of an associated form of arthritis

A new study finds that children with Down syndrome are at an increased risk of an associated form of arthritis.

10 Nov 2019

Does Parkinson's disease start in the brain or gut?

Does Parkinson's disease start in the brain or the gut? In a new contribution published in the Journal of Parkinson's Disease, scientists hypothesize that PD can be divided into two subtypes: gut-first, originating in the peripheral nervous system of the gut and spreading to the brain; and brain-first, originating in the brain, or entering the brain via the olfactory system, and spreading to the brainstem and peripheral nervous system.

7 Nov 2019

Potential side effects increase in children with use of common reflux aids, study shows

Proton Pump Inhibitors (PPIs) -- such as Prilosec, Protonix and Nexium, have long been one of the most prescribed medications in the country to aid in the reduction of stomach acid.

7 Nov 2019

Tumor cell plasticity counts during cancer metastasis

Cancer metastasis, which is the propagation of tumor cells into distant organs, is the leading cause of cancer patient mortality.

5 Nov 2019

Signs of frailty could be identified through a new assessment

Signs of frailty, and the risks it brings, could be identified in young and old people alike through a new assessment developed in a study led by researchers at the University of Strathclyde.

5 Nov 2019

Tumour conversion of glial cells when exposed to bowel cancer secretions

A new study has shown that glial cells of the gut (part of the enteric nervous system) when exposed to secretions from colon cancer cells are convert into tumours themselves. These altered glial cells then convert into promoters of tumours said the study researchers.

31 Oct 2019

Chemotherapy-induced senescent cells eat neighboring cells

A new study has found that chemotherapy-induced senescent cancer cells feed on other neighboring cells to enhance their survival.

30 Oct 2019

UChicago researchers reveal the secret of cancer-related Warburg effect

A new study, led by researchers at the University of Chicago, provides an answer to why cancer cells consume and use nutrients differently than their healthy counterparts and how that difference contributes to their survival and growth.

23 Oct 2019

Study dispels the hypothesis that metformin could help exercising seniors gain more muscle mass

A clinical trial initiated by University of Kentucky researchers argues against the hypothesis that the diabetes drug metformin could help exercising seniors gain more muscle mass. The double-blind trial, conducted at the University of Kentucky and University of Alabama at Birmingham, found that older adults who took metformin while performing rigorous resistance exercise training had smaller gains in muscle mass than the placebo group.

22 Oct 2019

Researchers elucidate properties of blood factor involved in weight loss and aging

Aging is a process that affects all functions of the human body, particularly brain function. However, aging can be delayed through lifestyle changes (physical exercise, restricting calorie intake, etc.).

22 Oct 2019

Study blunts hopes that diabetes drug could help exercising seniors gain more muscle mass

A new clinical trial dispels the hypothesis that the diabetes drug metformin could help exercising seniors gain more muscle mass.

22 Oct 2019

Oncolytics Biotech and PrECOG collaborate to study metastatic breast cancer

Oncolytics Biotech Inc. , currently developing pelareorep, an intravenously delivered immuno-oncolytic virus, and PrECOG LLC, a leading cancer research network, today announced their collaboration in which PrECOG will run the BRACELET-1 (PrE0113) study.

22 Oct 2019

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Huntington's disease (HD) is a fatal hereditary disease for which there is no cure. A novel study from Cedars-Sinai Medical Center, Los Angeles, using pluripotent stem cells advances understanding of how the disease develops and may help pave the way for identifying pathways for future treatments.

21 Oct 2019

Default response to spinal disc injuries can be temporarily stopped to allow for better treatment

Researchers may have found a way to press pause on spinal disc injuries, giving doctors more time to treat them before worse issues develop.

14 Oct 2019

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

In continuing efforts to find novel ways to kill cancer cells, researchers at the University of Maryland School of Medicine have identified a new pathway that leads to the destruction of cancer cells.

14 Oct 2019

Is mental illness being diagnosed correctly?

An important new piece of research appearing in the journal JAMA Psychiatry questions the accuracy of current diagnostic methods used in mental illness, and the true relevance of the diagnoses to the underlying disturbances in the brain’s function.

10 Oct 2019

Study pinpoints a gene that allows chlamydia to pick up DNA from host environment

According to the Centers for Disease Control and Prevention, chlamydia trachomatis is the most commonly reported sexually transmitted bacterial disease in the U.S., totaling 1.7 million cases in 2017. Rates are highest among teenagers and young adults. Left untreated, chlamydia can cause blindness and sterility.

10 Oct 2019

Phenotype News and Research

Leukemia type B cell can transform into a macrophage through epigenetic changes

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

Impaired liver function during pregnancy can lead to impaired metabolism and weight gain

Children with Down syndrome at greater risk of an associated form of arthritis

Does Parkinson's disease start in the brain or gut?

Potential side effects increase in children with use of common reflux aids, study shows

Tumor cell plasticity counts during cancer metastasis

Signs of frailty could be identified through a new assessment

Tumour conversion of glial cells when exposed to bowel cancer secretions

Chemotherapy-induced senescent cells eat neighboring cells

UChicago researchers reveal the secret of cancer-related Warburg effect

Study dispels the hypothesis that metformin could help exercising seniors gain more muscle mass

Researchers elucidate properties of blood factor involved in weight loss and aging

Study blunts hopes that diabetes drug could help exercising seniors gain more muscle mass

Oncolytics Biotech and PrECOG collaborate to study metastatic breast cancer

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Default response to spinal disc injuries can be temporarily stopped to allow for better treatment

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

Is mental illness being diagnosed correctly?

Study pinpoints a gene that allows chlamydia to pick up DNA from host environment

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