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Concern over tattoo-related infections

More care should be taken to prevent infections associated with tattooing, suggest researchers who describe a series of tattoo-related Mycobacterium chelonae infections in the USA.

24 Aug 2012

Lilly’s solanezumab Phase 3 trials on AD do not meet primary endpoints

Eli Lilly and Company today announced that the primary endpoints, both cognitive and functional, were not met in either of the two Phase 3, double-blind, placebo-controlled solanezumab EXPEDITION trials in patients with mild-to-moderate Alzheimer's disease.

24 Aug 2012

CDC reports worst West Nile virus outbreak in the U.S.

This past year's mild winter and wet spring could be contributing to the worst West Nile virus outbreak since the disease was first detected in the United States in 1999. According to the Centers for Disease Control and Prevention, there have been more cases of the virus so far this year than any year. As of August 14, almost 700 cases had been reported across the nation, including 26 deaths. This year also marks the earliest reported case of West Nile virus in New Jersey.

18 Aug 2012

Viewpoints: Calif. health exchange off to good start; Fay Vincent on access problems for disabled; How 'upcoding' increases health costs

The California Health Benefits Exchange, established under the Patient Protection and Affordable Care Act to offer subsidized private coverage to most of the uninsured, represents an excellent opportunity to improve the quality and cost of healthcare in this state.

18 Aug 2012

Longer looks: A jack-of-all-trades surgeon takes care of Nantucket; Psychiatrist's controversial effort to use brain scans to diagnose mental problems

Dr. Tim Lepore, 67, is a jack-of-all-trades general surgeon, tending to the 10,000 full-time residents of the Massachusetts island of Nantucket and to the many thousand more rich and famous summer-dwellers. Dr. Lepore has dealt with everything from poison ivy and tick-borne illnesses to narcolepsy and toe tourniquet syndrome (when a mother's hair wraps around a baby's toe, cutting off circulation). He counsels alcoholics, and allows patients to barter for health care. He once accepted oatmeal cookies from an immigrant worker who had no money for treatment.

17 Aug 2012

Pay more than lip service to sun-screen advice for antihypertensive users

Users of common antihypertensive drugs, such as hydrochlorothiazide and nifedipine, may be at increased risk for developing lip cancer.

9 Aug 2012

First generic versions of Singulair receive FDA approval for treatment of asthma, allergies

The U.S. Food and Drug Administration today approved the first generic versions of Singulair (montelukast sodium) for use in adults and children to control asthma symptoms and to help relieve symptoms of indoor and outdoor allergies.

6 Aug 2012

EC approves Vertex's KALYDECO for treatment of cystic fibrosis

Vertex Pharmaceuticals Incorporated announced today that the European Commission has approved KALYDECOTM (ivacaftor) for people with cystic fibrosis (CF) ages 6 and older who have at least one copy of the G551D mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

28 Jul 2012

Latest polypill trial yields largest improvements yet

The results of the first trial to administer the polypill on the basis of age alone has shown the largest reductions in blood pressure and cholesterol level of any polypill trial to date, researchers report.

24 Jul 2012

Once-daily Gralise significantly reduces pain intensity in PHN patients

Depomed, Inc. today announced that a report of Phase 3 data published online this month, ahead of the print edition, in the Clinical Journal of Pain showed that once-daily Gralise (gabapentin) tablets (1,800 mg) formulation significantly reduces intensity of pain in patients with postherpetic neuralgia (PHN).

23 Jul 2012

Novartis receives FDA approval for Afinitor to treat HER2-negative breast cancer

The U.S. Food and Drug Administration today approved Afinitor (everolimus) for use in combination with Aromasin (exemestane) to treat certain postmenopausal women with advanced hormone-receptor positive, HER2-negative breast cancer.

21 Jul 2012

Kawasaki Disease may increase risk of atherosclerosis in children

Cedars-Sinai researchers have linked Kawasaki Disease, a serious childhood illness that causes inflammation of blood vessels throughout the body, with early-onset and accelerated atherosclerosis, a leading cause of heart disease in adults.

18 Jul 2012

Children at increased risk for heat-related illness

Extreme heat continues to plague the nation with many areas seeing record temperatures. Though everyone needs to take precautions when it comes to dangerous heat, it's especially important to watch your kids. Children are at a greater risk than adults of sustaining a heat injury.

4 Jul 2012

Signs that a child is seriously ill: Interview with Professor Middleton

There are several signs that indicate that a child is seriously ill. These can be spotted by parents, teachers and carers as well as by me or any other doctor or nurse.

4 Jul 2012

Once-daily pill for HIV is a safe and effective alternative to traditional antiretroviral regimens

A new once-daily pill combining three antiretrovirals and a booster molecule is a safe and effective alternative to two widely used drug regimens for newly diagnosed HIV-positive adults who have had no previous treatment. The findings of two large international randomised trials published in this week’s Lancet also indicate that the new “Quad” pill is faster acting, doesn’t have the neuropsychiatric side effects associated with other combinations, and could improve compliance with treatment.

29 Jun 2012

Awaiting a court decision: Would consumers love the law if they suddenly lose it?; The market can fix health care

I still harbor the perhaps naïve hope that some conservative justices -- Anthony Kennedy? John Roberts? -; will pull back from judicial activism and allow the voters to decide the fate of the health-care law in this fall's elections. And here is where the court's reintroduction of the health-care issue into the political debate could be turned into a blessing by allies of reform, provided they take advantage of the opportunity to do what they have never done adequately up to now. They need, finally, to describe and defend the law and what it does.

26 Jun 2012

Roseola virus behind one-third of febrile seizures in young children

Researchers have discovered that infection with two of the roseola viruses, which are responsible for a common childhood rash, appear to increase a child’s risk for prolonged seizures and fever and may increase future temporal lobe epilepsy risk.

20 Jun 2012

Updated data from ARIAD’s ponatinib pivotal trial on CML or Ph+ ALL

ARIAD Pharmaceuticals, Inc. today announced updated clinical data from the pivotal PACE trial of its investigational pan-BCR-ABL inhibitor, ponatinib, in patients with chronic myeloid leukaemia (CML) or Philadelphia-positive acute lymphoblastic leukaemia (Ph+ ALL), who are resistant or intolerant to dasatinib or nilotinib or who have the T315I mutation.

18 Jun 2012

Anti-TNFs increase risk for herpes zoster infections in IRD patients

Patients with inflammatory rheumatic diseases who are treated with anti-tumor necrosis factor medications are significantly more likely to experience herpes zoster infections than those treated with traditional disease-modifying anti-rheumatic drugs, study results show.

15 Jun 2012

Rheumatism drugs may increase shingles risk

Patients with inflammatory rheumatic disease treated with one of the most effective medicines for their disease face a substantially increased risk for developing shingles, warn European researchers who suggest vaccination may be an option.

15 Jun 2012