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One cup of coffee a day could keep atrial fibrillation from coming back

A multicenter randomized clinical trial found that moderate caffeinated coffee intake after cardioversion significantly lowered the recurrence of atrial fibrillation or flutter compared with abstinence. The findings challenge long-standing advice to avoid coffee in cardiac arrhythmia patients and support its safety at typical consumption levels.

10 Nov 2025

Study provides insights into the obesity–breast cancer link

Obesity and cancer are two major health challenges of our time, yet the link between them remains only partially understood.

10 Nov 2025

Study identifies thyroid hormone pathway as key player in prostate cancer development

A hormone produced in the thyroid gland can play a key role in the development of prostate cancer.

10 Nov 2025

Weight loss drugs used by patients with high triglycerides do not increase pancreatitis risk

In a major new study, researchers from Intermountain Health in Salt Lake City have found that weight loss drugs used by patients who have high triglycerides do not increase their risk of pancreatitis or adverse cardiac events.

10 Nov 2025

Complete revascularization reduces the risk of death from cardiovascular causes

Opening all blocked arteries with stents in patients with a heart attack, known as complete revascularization, reduces the risk of death from cardiovascular causes, death from any cause and future heart attacks compared with opening only culprit artery causing the heart attack according to a new, large international study led by researchers at the Population Health Research Institute (PHRI), a joint organization of McMaster University and Hamilton Health Sciences.

10 Nov 2025

Genetic and cellular mechanisms underlying steatotic liver disease

Steatotic liver disease (SLD), mainly encompassing metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and metabolic dysfunction and ALD (MetALD), has emerged as the dominant cause of chronic liver disease worldwide, displacing viral hepatitis as the primary aetiology.

10 Nov 2025

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

Regular orange juice consumption reprograms immune-cell gene activity linked to blood pressure, lipid metabolism, and inflammation in healthy adults. The molecular effects differ by body weight, suggesting BMI-tailored benefits from this everyday beverage.

9 Nov 2025

New NIH grants fuel research in oral cancer treatment and pain relief

Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University of Texas at San Antonio, have been awarded three multi-year grants totaling $6 million from the National Institutes of Health to address treatment and pain management for oral cancer.

7 Nov 2025

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

A new radioimmunotherapy approach has the potential to cure human epidermal growth factor receptor 2 (HER2)-positive breast cancer, according to new research published in the November issue of The Journal of Nuclear Medicine.

7 Nov 2025

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

Intravenous immunoglobulin (IVIG) therapy involves infusing patients with naturally occurring IgG antibodies to treat autoimmune conditions.

7 Nov 2025

Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer

Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden driven primarily by persistent high-risk HPV infection and genetic susceptibility.

7 Nov 2025

Comprehensive kinase atlas reveals new insights into cell signaling and disease

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

Finerenone offers hope for kidney protection in patients with type 1 diabetes

The drug finerenone has a positive effect on patients with type 1 diabetes and chronic kidney disease.

6 Nov 2025

Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

Lowering the transcription factor PU.1 reprograms microglia into a neuroprotective, lymphoid-like state that compacts amyloid, blocks tau spread, and preserves synapses in Alzheimer’s disease. Microglial CD28 signaling helps restrain inflammation, revealing a regulatory switch that may inform future immunotherapies targeting microglia rather than neurons.

6 Nov 2025

Combination therapy offers hope for ending lifelong chronic lymphocytic leukemia treatment

Ianalumab targets the B-cell activating factor receptor (BAFR) and ibrutinib belongs to a class of therapeutics called Bruton's tyrosine kinase inhibitors (BTKi).

6 Nov 2025

New combination treatment overcomes resistance in ER positive breast cancer

In preclinical studies, researchers at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, have tested a new combination therapy for hormone-resistant, estrogen receptor-positive (ER+) breast cancer and were able to shrink tumors, reduce the number of cancer stem cells and reprogram the immune environment to be less supportive of cancer growth.

6 Nov 2025

Survival times continue to rise for people with advanced breast cancer

People diagnosed with advanced breast cancer in 2025 can expect to live for an extra six or seven months, compared to the average survival time for patients diagnosed in 2011, according to a major study of patient data in the US presented at the Advanced Breast Cancer Eighth International Consensus Conference (ABC8).

5 Nov 2025

Receptor News and Research

One cup of coffee a day could keep atrial fibrillation from coming back

Study provides insights into the obesity–breast cancer link

Study identifies thyroid hormone pathway as key player in prostate cancer development

Weight loss drugs used by patients with high triglycerides do not increase pancreatitis risk

Complete revascularization reduces the risk of death from cardiovascular causes

Genetic and cellular mechanisms underlying steatotic liver disease

Drinking orange juice daily may fine-tune genes tied to cardiovascular wellness

New NIH grants fuel research in oral cancer treatment and pain relief

New radioimmunotherapy approach shows potential to cure HER2-positive breast cancer

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer

Comprehensive kinase atlas reveals new insights into cell signaling and disease

Finerenone offers hope for kidney protection in patients with type 1 diabetes

Alzheimer’s breakthrough reveals how tweaking one gene shields brain connections

Combination therapy offers hope for ending lifelong chronic lymphocytic leukemia treatment

New combination treatment overcomes resistance in ER positive breast cancer

Survival times continue to rise for people with advanced breast cancer

Newly identified microglia subtype offers protection against Alzheimer’s disease

Opioid receptors caught in motion offering clues for safer painkillers

PTGES3 emerges as key regulator of androgen receptor in prostate cancer

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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