Ribonucleic Acid News and Research

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Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

An experimental mRNA-based vaccine against all 20 known subtypes of influenza virus provided broad protection from otherwise lethal flu strains in initial tests, and thus might serve one day as a general preventative measure against future flu pandemics, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

25 Nov 2022

The potential of Sofosbuvir against COVID-19 neurological symptoms

Researchers discuss how SARS-CoV-2 infects cortical neurons and damages their synapses that form the connection between brain cells.

25 Nov 2022

Can SARS-CoV-2 be inactivated by resonance caused by sound waves at the ultrasound frequency?

Researchers performed in vitro experiments to test the ability of different frequencies of ultrasound to inactivate SARS-CoV-2.

23 Nov 2022

Bivalent mRNA vaccines could enhance protective efficacy against COVID-19

A new study presents evidence suggestive of restored or increased efficacy from changing the formulation of COVID-19 vaccines to a bivalent one.

23 Nov 2022

New York sewer rats are easily infected by SARS-CoV-2, according to new study

Researchers evaluated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure among rats inhabiting New York City (NYC) during the fall of 2021.

23 Nov 2022

Fungi detected in 35 cancer types, often intracellular

In a recent article published in the journal Cell, researchers found fungal deoxyribonucleic acid (DNA) and cells at low abundances across many human cancers, with cancer type-dependent variations in fungus community composition and fungal-bacteriome interactions.

22 Nov 2022

Myocarditis after COVID vaccination is rare but higher in younger males

In a recent study published in the Canadian Medical Association Journal, researchers observed the incidence of myocarditis following messenger ribonucleic acid (mRNA)-based vaccination against coronavirus disease 2019 (COVID-19). Additionally, they compared their estimates with expected rates based on the historical rates assessed before the COVID-19 vaccination rollout in British Columbia (BC), Canada.

22 Nov 2022

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

Does a vasectomy change the semen microbiome?

Researchers investigate alterations in the semen microbiome before and after the vasectomy procedure.

22 Nov 2022

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

In a recent study, researchers used proteomic analysis to identify novel immune cell phenotypes associated with severe coronavirus disease 2019 (COVID-19).

22 Nov 2022

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Researchers mapped spatial, cellular, and molecular interactions of host and tumor-associated bacteria within the tumor microenvironment.

22 Nov 2022

Beetroot juice appears to affect gut microbiome, positively impacting intestinal and systemic health

In a recent study published in the Food Chemistry journal, researchers investigated the impact of consuming red beetroot juice for two weeks on gut microbiota.

21 Nov 2022

Kiwira virus: a new bat-borne hantavirus detected in Africa

Researchers discover a novel hantavirus called the Kiwira virus.

21 Nov 2022

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

A third COVID-19 vaccine dose in this patients with blood cancers could enhance their antibody responses against SARS-CoV-2

21 Nov 2022

Frozen and viable: successful culture of replicating SARS-CoV-2 from hospital aerosol samples after freezing

Researchers demonstrated the presence of infectious SARS-CoV-2 in samples from the hospital rooms of SARS-CoV-2-infected patients.

21 Nov 2022

Study suggests bats are an underrecognized arenavirus reservoir

Researchers reported the detection of arenavirus RNA from various species of bats sampled between 2007 and 2011 from Brazil.

21 Nov 2022

Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

20 Nov 2022

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

On November 17, 2022, the US Food and Drug Administration (FDA) approved a pathbreaking new drug called Tzield. This injectable formulation contains a combination of two drugs that could push back the onset of type 1 diabetes (T1D) in adults at stage 3 and children aged eight years or more at stage 2.

20 Nov 2022

Bombali ebolavirus has been detected among bats in Mozambique

Researchers reported on the detection of Bombali virus (BOMV, of the ebolavirus genus) ribonucleic acid (RNA) among three free-tailed Mops condylurus (Molossidae) bat species in Mozambique.

18 Nov 2022

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

In a recent study published in the journal Cell Reports, researchers in Cincinnati, USA, assessed the impact of dietary alteration to a high-fat diet (HFD) on the intestine.

17 Nov 2022

Ribonucleic Acid News and Research

Multivalent mRNA-based vaccine may serve as a preventative measure against future flu pandemics

The potential of Sofosbuvir against COVID-19 neurological symptoms

Can SARS-CoV-2 be inactivated by resonance caused by sound waves at the ultrasound frequency?

Bivalent mRNA vaccines could enhance protective efficacy against COVID-19

New York sewer rats are easily infected by SARS-CoV-2, according to new study

Fungi detected in 35 cancer types, often intracellular

Myocarditis after COVID vaccination is rare but higher in younger males

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

Does a vasectomy change the semen microbiome?

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

Microniches of intratumoral microbiota impact spatial and cellular heterogeneity in cancer

Beetroot juice appears to affect gut microbiome, positively impacting intestinal and systemic health

Kiwira virus: a new bat-borne hantavirus detected in Africa

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

Frozen and viable: successful culture of replicating SARS-CoV-2 from hospital aerosol samples after freezing

Study suggests bats are an underrecognized arenavirus reservoir

Rutgers scientists develop new approach to effectively shut down viral infections

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

Bombali ebolavirus has been detected among bats in Mozambique

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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