Toxin News and Research

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Allergan Licenses Rights To Medytox Candidates, In Up-To-$362M Deal

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26 Sep 2013

Botox Cosmetic receives FDA approval for treatment of crow’s feet lines

The U.S. Food and Drug Administration today approved a new use for Botox Cosmetic (onabotulinumtoxinA) for the temporary improvement in the appearance of moderate to severe lateral canthal lines, known as crow’s feet, in adults. Botox Cosmetic is the only FDA approved drug treatment option for lateral canthal lines.

12 Sep 2013

Research: New pathway plays role in fighting gut infection

The researchers found virulent E. coli bacteria blocked a pathway that would normally protect the gut from infection. These infections are particularly serious in young children and can result in diarrhoea and other complications such as kidney damage.

12 Sep 2013

Large study shows effective test for diagnosis of C-Diff infection

The largest study of its kind has shown the most effective test for the diagnosis of Clostridium difficile (C-Diff), a bacterial infection which causes 15,000-20,000 deaths a year in hospitals in the United States.

4 Sep 2013

Research findings may help scientists develop anthrax treatments for humans

Researchers at the National Institute of Allergy and Infectious Diseases and the National Heart, Lung, and Blood Institute, both part of the National Institutes of Health, have identified the cells in two distinct areas of the body that are simultaneously targeted for damage by anthrax toxins, eventually causing illness and sometimes death. Their findings, which appeared online today in Nature, are based on testing in mice.

29 Aug 2013

Human exposure to aluminium implicates number of chronic diseases

Aluminium - the most abundant metal and third most abundant element of the Earth's crust - has no known biological function and is a recognised environmental toxin. Human exposure to aluminium is implicated in a number of chronic diseases, including bone disease, auto-immune conditions, cancer and neurodegenerative diseases.

28 Aug 2013

Study reveals role of cadherin receptor BT-R3 in killing action of Cry4B mosquito toxin

Researchers at The University of Texas at Dallas (UTD), led by Dr. Lee Bulla, have demonstrated for the first time the selective cytotoxicity of Bacillus thuringiensis subsp. israelensis Cry4B toxin is mediated by BT-R3.

27 Aug 2013

Levels of mercury in Pacific Ocean fish likely to increase in coming decades

University of Michigan researchers and their University of Hawaii colleagues say they've solved the longstanding mystery of how mercury gets into open-ocean fish, and their findings suggest that levels of the toxin in Pacific Ocean fish will likely rise in coming decades.

26 Aug 2013

NIST and USAMRIID scientists advance crucial step in anthrax infection process

A new hypothesis concerning a crucial step in the anthrax infection process has been advanced by scientists at the National Institute of Standards and Technology (NIST) and the U.S. Army Medical Research Institute for Infectious Diseases (USAMRIID) at Fort Detrick, Md.

21 Aug 2013

Study shows superantigens produced by staph bacteria cause infective endocarditis and sepsis

University of Iowa researchers have discovered what causes the lethal effects of staphylococcal infective endocarditis - a serious bacterial infection of heart valves that kills approximately 20,000 Americans each year.

20 Aug 2013

DNA mutation 'signature' identified in urinary tract cancers linked to birthwort herb

Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation.

8 Aug 2013

Cancer-linked mitosis: an interview with Professor Scott Kern, Johns Hopkins University School of Medicine

Mitosis is the process by which a cell gives rise to two daughter cells. It’s the basis behind the growth of the human body, the renewal of the human body as it ages, and unfortunately, the growth of cancers.

7 Aug 2013

Discovery brings scientists one step closer to understanding challenges linked to mercury cleanup

More forms of mercury can be converted to deadly methylmercury than previously thought, according to a study published Sunday in Nature Geoscience. The discovery provides scientists with another piece of the mercury puzzle, bringing them one step closer to understanding the challenges associated with mercury cleanup.

6 Aug 2013

Combating antibiotic resistance: an interview with Ron Najafi, CEO NovaBay Pharmaceuticals

Approximately 80 years ago the first antibiotic was discovered by Sir Alexander Fleming, for which he was justifiably awarded the Nobel Prize in medicine.

2 Aug 2013

Scientists reveal biochemical pathway responsible for manufacturing glycoalkaloids

In 1924, Science magazine reported on a fatal case of potato poisoning: James B. Matheney of Vandalia, Illinois, had gathered about one and a half bushels of tubers, which had turned green due to sunlight exposure.

1 Aug 2013

New needle-free treatment may dramatically reduce global snakebite fatalities

A team of researchers led by Dr. Matt Lewin of the California Academy of Sciences, in collaboration with the Department of Anesthesia at the University of California, San Francisco, has pioneered a novel approach to treating venomous snakebites-administering antiparalytics topically via a nasal spray.

31 Jul 2013

Piramal's Healthcare invests USD 2.5 million to upgrade ADC manufacturing suites

Piramal's Healthcare vertical today announced that it is to invest USD 2.5 million at its FDA approved Grangemouth, UK, site to upgrade one of its antibody drug conjugate (ADC) manufacturing suites, from clinical phase to commercial grade, in response to customer demand.

26 Jul 2013