Toxin News and Research

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MGH investigators identify molecule that plays key role in the breakdown of kidney filter

One of the most devastating side effects of diabetes is kidney failure, and one of the earliest signs of kidney damage is a disruption of the organ's filtering capacity. Diabetes patients who develop kidney failure must go on dialysis, seriously limiting their quality of life and placing them at significantly increased risk of death. The incidence of kidney disease is increasing with rising rates of obesity-associated type 2 diabetes, but very little progress has been made towards protecting the kidney's filter barrier during the past 50 years.

16 Nov 2013

Researchers exploit power of evolution to create new drug for use against heart disease

An international team of researchers led by the University of Leicester has "harnessed the power of evolution" to create a new drug for possible use against heart disease, inflammation and other illnesses.

15 Nov 2013

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Making fat cells immortal might seem like a bad idea to most people, but for a team of University of Iowa scientists it was the ideal way to study how the interaction between bacteria and fat cells might contribute to diabetes.

31 Oct 2013

Scientists identify new toxic entity associated with dementia and motor neuron disease

A new toxic entity associated with genetically inherited forms of dementia and motor neuron disease has been identified by scientists at the UCL Institute of Neurology. The toxin is the result of a genetic mutation that leads to the production of RNA molecules which could be responsible for the diseases. The findings are published in the journal Acta Neuropathologica.

31 Oct 2013

New finding could help lead to better treatments for eczema

For the millions of people suffering from the intensely red, horribly itchy skin condition known as eczema, the only thing more maddening than their disease is the lack of understanding of what causes it, or makes it flare up from time to time.

31 Oct 2013

Canadian researchers contribute to the science of verotoxigenic E. coli and associated infections

Many Canadian scientists and clinicians were unsung heroes during the early years (1977-1983) of research unfolding around verotoxigenic E. coli (VTEC).

30 Oct 2013

Dialysis while sleeping improves kidney health and decreases risk of heart disease

Montreal- Receiving dialysis at home while sleeping not only improves kidney health and quality of life for people with kidney disease, it could also decrease their risk of heart disease, says new study presented at the Canadian Cardiovascular Congress.

18 Oct 2013

Researchers identify C. perfringens type B bacteria believed to trigger multiple sclerosis

A research team from Weill Cornell Medical College and The Rockefeller University has identified a bacterium it believes may trigger multiple sclerosis, a chronic, debilitating disorder that damages myelin forming cells in the brain and spinal cord.

18 Oct 2013

Scientists identify recessive gene mutation that reduces certain protein affecting brain development

Though worlds apart, four unrelated families have been united in a medical mystery over the source of a rare inherited disorder that results in their children being born with abnormal brain growth and severe functional impairments.

17 Oct 2013

Research findings point the way to new class of antibiotics for skin and heart infections

Researchers at NYU Langone Medical Center have discovered a new mechanism by which the deadly Staphylococcus aureus bacteria attack and kill off immune cells. Their findings, published today in the journal Cell Host & Microbe, explain a critical survival tactic of a pathogen that causes more skin and heart infections than any other microbe, and kills more than 100,000 Americans every year.

17 Oct 2013

Scientists decode key molecular gateway for toxin that causes botulism

U.S. and German scientists have decoded a key molecular gateway for the toxin that causes botulism, pointing the way to treatments that can keep the food-borne poison out of the bloodstream.

12 Oct 2013

Molecular Templates secures $8.5M series C financing plus $10.6M grant from CPRIT

Molecular Templates, Inc., a biopharmaceutical company focused on the discovery and development of a new class of biologic therapeutics, announced today that it recently secured an $8.5M series C financing led by Excel Venture Management. Santé Ventures, an existing investor, also participated in the round.

9 Oct 2013

Using Botox as weight loss tool in rats

Researchers from the Norwegian University of Science and Technology have had promising experimental results from using Botox as a weight loss tool in rats. The research group hopes to win approval for human testing in the near future.

5 Oct 2013

Mexican scientists reveal aflatoxins relationship with cervical and liver cancer in humans

Mexican scientists identified and quantified the amount of aflatoxins (carcinogenic) in food such as corn tortilla, rice, chili pepper, processed sauces, chicken breast and eggs, and revealed its relationship with cervical and liver cancer in humans.

1 Oct 2013

Allergan Licenses Rights To Medytox Candidates, In Up-To-$362M Deal

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26 Sep 2013

Botox Cosmetic receives FDA approval for treatment of crow’s feet lines

The U.S. Food and Drug Administration today approved a new use for Botox Cosmetic (onabotulinumtoxinA) for the temporary improvement in the appearance of moderate to severe lateral canthal lines, known as crow’s feet, in adults. Botox Cosmetic is the only FDA approved drug treatment option for lateral canthal lines.

12 Sep 2013

Research: New pathway plays role in fighting gut infection

The researchers found virulent E. coli bacteria blocked a pathway that would normally protect the gut from infection. These infections are particularly serious in young children and can result in diarrhoea and other complications such as kidney damage.

12 Sep 2013

Large study shows effective test for diagnosis of C-Diff infection

The largest study of its kind has shown the most effective test for the diagnosis of Clostridium difficile (C-Diff), a bacterial infection which causes 15,000-20,000 deaths a year in hospitals in the United States.

4 Sep 2013

Research findings may help scientists develop anthrax treatments for humans

Researchers at the National Institute of Allergy and Infectious Diseases and the National Heart, Lung, and Blood Institute, both part of the National Institutes of Health, have identified the cells in two distinct areas of the body that are simultaneously targeted for damage by anthrax toxins, eventually causing illness and sometimes death. Their findings, which appeared online today in Nature, are based on testing in mice.

29 Aug 2013

Human exposure to aluminium implicates number of chronic diseases

Aluminium - the most abundant metal and third most abundant element of the Earth's crust - has no known biological function and is a recognised environmental toxin. Human exposure to aluminium is implicated in a number of chronic diseases, including bone disease, auto-immune conditions, cancer and neurodegenerative diseases.

28 Aug 2013

Toxin News and Research

MGH investigators identify molecule that plays key role in the breakdown of kidney filter

Researchers exploit power of evolution to create new drug for use against heart disease

Interaction between fat cells and bacterial toxins can lead to chronic inflammation

Scientists identify new toxic entity associated with dementia and motor neuron disease

New finding could help lead to better treatments for eczema

Canadian researchers contribute to the science of verotoxigenic E. coli and associated infections

Dialysis while sleeping improves kidney health and decreases risk of heart disease

Researchers identify C. perfringens type B bacteria believed to trigger multiple sclerosis

Scientists identify recessive gene mutation that reduces certain protein affecting brain development

Research findings point the way to new class of antibiotics for skin and heart infections

Scientists decode key molecular gateway for toxin that causes botulism

Molecular Templates secures $8.5M series C financing plus $10.6M grant from CPRIT

Using Botox as weight loss tool in rats

Mexican scientists reveal aflatoxins relationship with cervical and liver cancer in humans

Allergan Licenses Rights To Medytox Candidates, In Up-To-$362M Deal

Botox Cosmetic receives FDA approval for treatment of crow’s feet lines

Research: New pathway plays role in fighting gut infection

Large study shows effective test for diagnosis of C-Diff infection

Research findings may help scientists develop anthrax treatments for humans

Human exposure to aluminium implicates number of chronic diseases

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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