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Case Western dental researcher discovers new way to model how T cells cause inflammation in mice

Case Western Reserve University dental researcher Pushpa Pandiyan has discovered a new way to model how infection-fighting T cells cause inflammation in mice.

23 Feb 2015

Evolution of two protein kinases may hold key to unlocking highly specific cancer drugs

This is the story of Abl and Src -- two nearly identical protein kinases whose evolution may hold the key to unlocking new, highly specific cancer drugs.

20 Feb 2015

Researchers develop novel approach to identify potential antimalarial drugs

Each year nearly 600,000 people--mostly children under age five and pregnant women in sub-Saharan Africa--die from malaria, caused by single-celled parasites that grow inside red blood cells. The most deadly malarial species--Plasmodium falciparum--has proven notoriously resistant to treatment efforts.

12 Feb 2015

First human clinical study of ChromaDex's NIAGEN nicotinamide riboside meets primary endpoint

ChromaDex Corp. announced today that the initial results of the first human clinical study for the company's NIAGEN nicotinamide riboside (NR) has met its primary endpoint.

11 Feb 2015

UNC researchers create new research tool to help crack the histone code

University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code. This research tool can be used to better understand the function of histone proteins, which play critical roles in the regulation of gene expression in animals and plants.

11 Feb 2015

Fungal infections rarely develop resistance to combination drug therapy

Researchers at the University of Toronto have discovered that Candida albicans -- a leading cause of potentially fatal hospital-acquired infections -- rarely develops resistance to combination drug therapy and, when it becomes resistant, it also becomes less dangerous.

9 Feb 2015

Research shows olfactory proxy detection is a phenomenon in both insects and humans

Antioxidants are natural food ingredients that protect cells from harmful influences. Their main task is to neutralize so-called "free radicals" which are produced in the process of oxidation and which are responsible for cell degeneration.

2 Feb 2015

ODIN project examines food-based solutions to prevent vitamin D deficiency

ODIN is a 4 year collaborative project with partners from all over Europe and one from the USA. The coordinator of the project is UCC and other Irish partners include the Daithi O'Murchu Marine Research Station, UCD, Crème Software Ltd (Dublin) and Monaghan Mushrooms.

2 Feb 2015

Scientists create largest ever catalogue of biological chimeras

Scientists from the Spanish National Cancer Research Centre's Structural Computational Biology Group, led by Alfonso Valencia, are making the largest ever catalogue of biological chimeras available to the public domain.

2 Feb 2015

Genes that increase longevity may not increase healthy lifespan

A study of long-lived mutant C. elegans by scientists at the University of Massachusetts Medical School shows that the genetically altered worms spend a greater portion of their life in a frail state and exhibit less activity as they age then typical nematodes.

22 Jan 2015

UH Case Medical Center researchers find that coenzyme A plays key role in cell metabolism

Case Western Reserve and University Hospitals Case Medical Center researchers and physicians have discovered that the molecule known as coenzyme A plays a key role in cell metabolism by regulating the actions of nitric oxide. Cell metabolism is the ongoing process of chemical transformations within the body's cells that sustains life, and alterations in metabolism are a common cause of human disease, including cancer and heart disease.

15 Jan 2015

Yeast-eating gut bacteria can help battle bowel problems and autoimmune diseases

Human gut bacteria that feast on the yeast contained in fermented foods like bread and beer provides clues to new treatments for people suffering from bowel diseases.

9 Jan 2015

Findings could accelerate development of prebiotic medicines for bowel problems, autoimmune diseases

Bacteria that have evolved to eat their way through yeast in the human gut could inform the development of new treatments for people suffering from bowel diseases.

8 Jan 2015

Gout attacks are most common at night

Research, published today, has shown that an acute gout attack is more than twice as likely to occur during the night or early morning hours as during the day. The increased prevalence of gout attacks at night time was observed even after 24 hours with no alcohol and low purine intake.

11 Dec 2014

Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Long known for its ability to help organisms successfully adapt to environmentally stressful conditions, the highly conserved molecular chaperone heat-shock protein 90 (HSP90) also enables estrogen receptor-positive (ER+) breast cancers to develop resistance to hormonal therapy.

10 Dec 2014

Tufts University study explores relationship between transcription, expansions of DNA repeats

Researchers in human genetics have known that long nucleotide repeats in DNA lead to instability of the genome and ultimately to human hereditary diseases such Freidreich's ataxia and Huntington's disease.

26 Nov 2014

Innovative tool could redefine limits of synthetic biology, improve study of yeast genetics

NYU Langone yeast geneticists report they have developed a novel tool -- dubbed "the telomerator" -- that could redefine the limits of synthetic biology and advance how successfully living things can be engineered or constructed in the laboratory based on an organism's genetic, chemical base-pair structure.

4 Nov 2014

Special issue of Technology and Innovation includes articles from Patents for Humanity winners

The current special issue of Technology and Innovation, is devoted to patents that benefit people around the world who live with limited resources, in challenging environments, and are in need of better access to basic needs and improved standards of living, health and infrastructure.

31 Oct 2014

Salk Institute scientists identify promising target for HIV/AIDS treatment

Like a slumbering dragon, HIV can lay dormant in a person's cells for years, evading medical treatments only to wake up and strike at a later time, quickly replicating itself and destroying the immune system.

27 Oct 2014

Study outlines how unique pathogen uses the release of ROS as signal to infect healthy people

New research into a rare pathogen has shown how a unique evolutionary trait allows it to infect even the healthiest of hosts through a smart solution to the body's immune response against it.

20 Oct 2014

Yeast News and Research

Case Western dental researcher discovers new way to model how T cells cause inflammation in mice

Evolution of two protein kinases may hold key to unlocking highly specific cancer drugs

Researchers develop novel approach to identify potential antimalarial drugs

First human clinical study of ChromaDex's NIAGEN nicotinamide riboside meets primary endpoint

UNC researchers create new research tool to help crack the histone code

Fungal infections rarely develop resistance to combination drug therapy

Research shows olfactory proxy detection is a phenomenon in both insects and humans

ODIN project examines food-based solutions to prevent vitamin D deficiency

Scientists create largest ever catalogue of biological chimeras

Genes that increase longevity may not increase healthy lifespan

UH Case Medical Center researchers find that coenzyme A plays key role in cell metabolism

Yeast-eating gut bacteria can help battle bowel problems and autoimmune diseases

Findings could accelerate development of prebiotic medicines for bowel problems, autoimmune diseases

Gout attacks are most common at night

Heat-shock protein 90 enables ER+ breast cancers to develop resistance to hormonal therapy

Tufts University study explores relationship between transcription, expansions of DNA repeats

Innovative tool could redefine limits of synthetic biology, improve study of yeast genetics

Special issue of Technology and Innovation includes articles from Patents for Humanity winners

Salk Institute scientists identify promising target for HIV/AIDS treatment

Study outlines how unique pathogen uses the release of ROS as signal to infect healthy people

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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