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Body weight change in older women may aid in diagnosis, management of Alzheimer's disease

Researchers led by Deborah Gustafson, PhD, MS, professor of neurology at SUNY Downstate Medical Center, have shown that women with a gene variant (APOEe4 allele) associated with Alzheimer's disease experience a steeper decline in body mass index (BMI) after age 70 than those women without the version of the gene, whether they go on to develop dementia or not.

6 Oct 2015

MS patients with history of neuro-ophthalmic syndromes perform poorly on visual neuropsychological testing

Scientists found that individuals with multiple sclerosis (MS) who had a history of neuro-ophthalmic syndromes performed poorly on visual neuropsychological tasks. The article, "Neuro-ophthalmic syndromes and processing speed in multiple sclerosis," was published in the Journal of Neuro-Ophthalmology.

6 Oct 2015

Researchers design specialized catheter for fixing holes in the heart

Researchers from Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard John A. Paulson School of Engineering and Applied Sciences and the Karp Lab at Brigham and Women's Hospital have jointly designed a specialized catheter for fixing holes in the heart using a biodegradable adhesive and patch.

6 Oct 2015

Novel computational strategy may help identify genetic variants that cause disease in children

The team behind the Deciphering Developmental Disorders (DDD) Study, one of the world's largest nationwide rare disease genome-wide sequencing initiatives, have developed a novel computational approach to identify genetic variants that cause disease in young children.

6 Oct 2015

Preoperative MRI use increasing in breast cancer

A Canadian research team reports a substantial increase in the use of preoperative magnetic resonance imaging over a 10-year period in women with newly diagnosed breast cancer.

2 Oct 2015

Early genetic diagnosis in neonatal diabetes a ‘new framework for clinical care’

Early genetic testing of babies with suspected neonatal diabetes identifies the underlying cause in more than 80% of cases, say researchers.

1 Oct 2015

Two studies identify promising new anti-retroviral strategy to combat HIV-1

A pair of studies by researchers at the University of Massachusetts Medical School, the University of Trento in Italy, and the University of Geneva in Switzerland, point to a promising new anti-retroviral strategy for combating HIV-1.

1 Oct 2015

New research sheds light on how retina sets its own biological rhythm using neuropsin

Researchers at Johns Hopkins and the University of Washington report new research that sheds light on how the retina sets its own biological rhythm using a novel light-sensitive pigment, called neuropsin, found in nerve cells at the back of the eye.

1 Oct 2015

Brodalumab therapy achieves 100% reduction in psoriasis symptoms

An experimental, biologic treatment, brodalumab, achieved 100 percent reduction in psoriasis symptoms in twice as many patients as a second, commonly used treatment, according to the results of a multicenter clinical trial led by Mount Sinai researchers and published online today in the New England Journal of Medicine.

1 Oct 2015

New study finds that serum miRNA profiles change as myeloma progresses

Virtually all patients who develop myeloma have an asymptomatic disease called monoclonal gammopathy of undetermined significance (MGUS) in the years before the onset of myeloma. The five-year relative survival rate for myeloma is 69% for patients diagnosed with stage I or localized disease, compared with 45% for patients with advanced cancer.

30 Sep 2015

University of Michigan-led team performs first kidney transplants in Ethiopia

A University of Michigan-led team performed the first kidney transplants in Ethiopia last week, after spending more than two years to help establish a transplant center in the African country.

30 Sep 2015

New gene therapy approach to treating DMD reduces symptoms, extends life span in mouse model

A gene therapy approach to treating the progressive muscle wasting disorder Duchenne muscular dystrophy (DMD) that does not replace the mutated DMD gene but instead delivers the gene for ITGA7, a protein in skeletal muscle, led to reduced symptoms and significantly extended life span in a mouse model of severe DMD. Over-expression of ITGA7 did not elicit an immune reaction, further supporting its potential as a novel treatment for DMD, according to a new study published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

30 Sep 2015

Collaborative approach may speed discovery of new preventive treatments for Alzheimer's disease

The future success of Alzheimer's prevention research could depend on the ability of researchers from different clinical trials to build collaborative relationships that facilitate the sharing of information, resources and expertise that may speed the discovery of new preventive treatments, according to leading Alzheimer's researchers who published a Perspectives article, "CAP--advancing the evaluation of preclinical Alzheimer disease treatments," online today in Nature Reviews Neurology.

30 Sep 2015

Stroke patients with spatial neglect more likely to fall and have longer stays in hospital

Using the Kessler Foundation Neglect Assessment Process (KF-NAP), Kessler researchers found a high rate of spatial neglect among inpatients with stroke. Affected patients had a higher risk for falls, longer lengths of stay and lesser likelihood of returning home after discharge.

30 Sep 2015

Majority of cancer patients lack access to safe, affordable surgical care

Over 80% of the 15 million people diagnosed with cancer worldwide in 2015 will need surgery, but less than a quarter will have access to proper, safe, affordable surgical care when they need it, according to a major new Commission examining the state of global cancer surgery, published in The Lancet Oncology, and being presented at the 2015 European Cancer Congress in Vienna, Austria.

29 Sep 2015

The Center for Bariatric Surgery receives MBSAQIP accreditation for safe, high-quality bariatric patient care

The Center for Bariatric Surgery has earned certification for adult and teen weight loss surgery under the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) which sets standards for safe, high-quality bariatric patient care.

29 Sep 2015

NIH's Human Placenta Project aims to revolutionize understanding of the placenta

The National Institutes of Health has announced $46 million in research awards for the Human Placenta Project, an initiative to revolutionize understanding of the placenta. The awards will fund technology development and testing to assess placental function throughout pregnancy, with the ultimate goal of improving pregnancy outcomes and lifelong health.

29 Sep 2015

Standard clomiphene treatment better than proposed alternative for unexplained fertility

It is estimated that approximately 10 percent of women of child-bearing age may be unable to get pregnant or to carry a pregnancy to term.

26 Sep 2015

New project aims to develop web-based tool for women considering CPM

Rutgers Cancer Institute of New Jersey surgical oncologist Laurie J. Kirstein, MD, FACS, and Associate Director for Cancer Prevention, Control and Population Science Sharon L. Manne, PhD, have been awarded a $404,089 grant (R21CA187643) from the National Cancer Institute to explore the decision making process women with non-hereditary breast cancer undergo when considering the removal of a healthy breast.

26 Sep 2015

Pediatric cancer diagnosis can take a significant toll on financial well-being of families

Almost one-third of families whose children were being treated for cancer faced food, housing or energy insecurity and one-quarter lost more than 40 percent of household income, according to a new study from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

26 Sep 2015

Medical School News and Research

Body weight change in older women may aid in diagnosis, management of Alzheimer's disease

MS patients with history of neuro-ophthalmic syndromes perform poorly on visual neuropsychological testing

Researchers design specialized catheter for fixing holes in the heart

Novel computational strategy may help identify genetic variants that cause disease in children

Preoperative MRI use increasing in breast cancer

Early genetic diagnosis in neonatal diabetes a ‘new framework for clinical care’

Two studies identify promising new anti-retroviral strategy to combat HIV-1

New research sheds light on how retina sets its own biological rhythm using neuropsin

Brodalumab therapy achieves 100% reduction in psoriasis symptoms

New study finds that serum miRNA profiles change as myeloma progresses

University of Michigan-led team performs first kidney transplants in Ethiopia

New gene therapy approach to treating DMD reduces symptoms, extends life span in mouse model

Collaborative approach may speed discovery of new preventive treatments for Alzheimer's disease

Stroke patients with spatial neglect more likely to fall and have longer stays in hospital

Majority of cancer patients lack access to safe, affordable surgical care

The Center for Bariatric Surgery receives MBSAQIP accreditation for safe, high-quality bariatric patient care

NIH's Human Placenta Project aims to revolutionize understanding of the placenta

Standard clomiphene treatment better than proposed alternative for unexplained fertility

New project aims to develop web-based tool for women considering CPM

Pediatric cancer diagnosis can take a significant toll on financial well-being of families

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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