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Newly designed three-part molecule shows promise to treat breast cancers

A newly designed three-part molecule could be the one answer patients with a certain form of breast cancer are looking for, scientists report.

22 Mar 2018

Immune cells can repopulate in the retina after elimination, mice study shows

Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute.

21 Mar 2018

Sentinel lymph node biopsies could be safely avoided for some breast cancer patients

Sentinel lymph node biopsies, where lymph nodes are surgically removed to check for signs of breast cancer spread, could be safely avoided for some women, according to research presented at the 11th European Breast Cancer Conference.

21 Mar 2018

New DOD grant to support testing of promising therapy for triple-negative breast cancer

A unique cell surface protein found on triple-negative type breast cancer cells called JAG1 is a promising new therapeutic target for this hard-to-treat and highly metastatic type of breast cancer, according to researchers at the University of Illinois at Chicago.

21 Mar 2018

Vitamin D deficiency linked to metabolic syndrome in postmenopausal women

Results of a study carried out in Brazil showed a strong association between vitamin D deficiency and metabolic syndrome in postmenopausal women.

21 Mar 2018

New study identifies key role for particular gene in 16p11.2 deletion syndrome

In a new study of one of the most common genetic causes of autism, neuroscientists at MIT's Picower Institute for Learning and Memory have identified a specific molecular mechanism that appears to undermine the ability of neurons in affected mice to properly incorporate changes driven by experience.

20 Mar 2018

American Gene Technologies receives second immuno-oncology patent

American Gene Technologies International Inc., a leading gene and cell therapy company, today announced receipt of a second immuno-oncology patent on the stimulation of gamma delta T cells for treating solid tumors in epithelial cancers.

20 Mar 2018

LSD reduces 'sense of self' - research

Dr Albert Hofmann, a Swiss chemist, first found the effects of LSD or lysergic acid diethylamide or “acid” on the psyche. It has been 75 years since his invention. Now new research finds deeper understanding of how this psychedelic chemical alters the perception and affects the brain.

19 Mar 2018

Treating metastatic breast cancer with immunotherapy

Breast cancer, in the stage with distant metastases, is an incurable disease with a 5 years survival rate of about 5-10%. Immunotherapy has recently improved survival in metastatic breast cancer patients with breast cancer harboring the expression of HER 2 receptor.

19 Mar 2018

New diabetes drug may help obese people shed body weight

A compound that mimics a naturally occurring hormone that regulates appetite may help people who have obesity but not diabetes to lose weight, a new study suggests.

19 Mar 2018

UH researchers improve understanding of autism spectrum disorders

Two University of Houston scientists are reporting that defects in a portion of the brain's hippocampus, called the dentate gyrus, is regulated by the nuclear receptor LXRβ (Liver X receptor Beta). The dentate gyrus, or DG, is responsible for emotion and memory and is known to be involved in autism spectrum disorders (ASD).

15 Mar 2018

University of Akron professor receives NSF grant for research that supports anti-cancer therapeutics

Dr. Adam W. Smith, assistant professor in the Department of Chemistry, has won a CAREER award from the National Science Foundation. The title of the award is "Lipid Regulation of Receptor Tyrosine Kinases" and provides $650,000 of funding for research.

15 Mar 2018

EPA ramps up efforts to create high-throughput endocrine disruptor assays

Exposure to endocrine-disrupting chemicals can cause health effects, such as reduced fertility and increased incidences of obesity and diabetes. Two decades ago, Congress directed the U.S. Environmental Protection Agency to screen substances for this activity.

14 Mar 2018

Scientists explore how to protect obese, premenopausal women from cardiovascular risk

Obese, premenopausal women can lose the innate protection from cardiovascular disease that their youth and estrogen are believed to afford, and scientists want to know how.

14 Mar 2018

Tumor's 'microenvironment' plays key role in altering therapeutic response of breast cancer

Cancer is typically thought of as a tumor that needs to be removed or an area that needs to be treated with radiation or chemotherapy. As a physicist and cancer researcher, Joe Gray, Ph.D., thinks differently.

14 Mar 2018

New findings yield insights into factors that contribute to aggressive endometrial tumors

New research from Huntsman Cancer Institute at the University of Utah indicates steroid and hormone receptors are simultaneously active in many endometrial cancer tissues.

13 Mar 2018

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

A team of Italian scientists reported this week that blocking the interaction between urokinase receptor (uPAR) and formyl peptide receptor type 1 (FPR1) suppresses the ability of melanoma cells to migrate, invade through an extracellular matrix, and to burrow through a layer of endothelial cells.

13 Mar 2018

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

Endocrine-disrupting chemicals are substances that interfere with the ability of endogenous hormones to regulate homeostasis via their cognate nuclear receptors.

13 Mar 2018

Two types of blood pressure medications linked to increased variability, higher risk of death

Two types of blood pressure medications - alpha blockers and alpha 2 agonist - show increased variability in blood pressure measurements between doctor visits, which is associated with an increased risk of death, according to new research from the Intermountain Medical Center Heart Institute in Salt Lake City.

13 Mar 2018

Scientists link 110 genes to increased risk of breast cancer

Scientists have linked 110 genes to an increased risk of breast cancer in the most comprehensive study ever to unpick the genetics of the disease.

13 Mar 2018

Receptor News and Research

Newly designed three-part molecule shows promise to treat breast cancers

Immune cells can repopulate in the retina after elimination, mice study shows

Sentinel lymph node biopsies could be safely avoided for some breast cancer patients

New DOD grant to support testing of promising therapy for triple-negative breast cancer

Vitamin D deficiency linked to metabolic syndrome in postmenopausal women

New study identifies key role for particular gene in 16p11.2 deletion syndrome

American Gene Technologies receives second immuno-oncology patent

LSD reduces 'sense of self' - research

Treating metastatic breast cancer with immunotherapy

New diabetes drug may help obese people shed body weight

UH researchers improve understanding of autism spectrum disorders

University of Akron professor receives NSF grant for research that supports anti-cancer therapeutics

EPA ramps up efforts to create high-throughput endocrine disruptor assays

Scientists explore how to protect obese, premenopausal women from cardiovascular risk

Tumor's 'microenvironment' plays key role in altering therapeutic response of breast cancer

New findings yield insights into factors that contribute to aggressive endometrial tumors

Continuous tracking of melanoma cell invasion helps scientists explain key regulators of metastasis

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

Two types of blood pressure medications linked to increased variability, higher risk of death

Scientists link 110 genes to increased risk of breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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