Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Narcotic medications can safely and effectively ease severe, chronic pain in older people with little risk that these patients will seek ever-increasing doses, University of California, San Francisco (UCSF) medical scientists have found. Younger patients, however, are likely to want to rapidly increase their medication dose, the researchers found, posing serious potential health consequences.

20 May 2005

Two out of three Americans with type-2 diabetes do not have their disease under control

According to a new survey two out of three Americans with type-2 diabetes do not have their disease under control and are putting themselves at risk of early deaths from stroke, heart attack or kidney failure as well as blindness and limb loss.

18 May 2005

Patients with type 2 diabetes who participate in group education programs require less medication

Group-based education resulted in improved diabetes control as reflected by blood glucose levels and patients’ knowledge of diabetes. Evidence also suggested that participants in diabetes group education programs may reduce their blood pressure and body weight and increase self-empowerment, quality of life, self-management skills and treatment satisfaction.

18 May 2005

Nutritional composition of a mother’s breast milk may depend not just on her diet - but on her genes

“It is well known that genes control the nutrient levels in cow’s milk” said Richard B. Weinberg, M.D. “But until now, no one has considered how genes might affect human breast milk. This is the first study to demonstrate a genetic effect on human lactation.” The results were presented today at Digestive Disease Week 2005 in Chicago, Ill.

18 May 2005

Hypertension drug combination yields high rate of blood pressure control in hard-to-treat patients

The study, conducted at the University of Maryland School of Medicine and 118 other sites, was focused on bringing down systolic blood pressure, the top number in a blood pressure reading, which is the more difficult number to bring down.

18 May 2005

Routinely reformatting computed tomography (CT) scans to view organs from several different directions may help radiologists improve diagnosis

"You can see things in one view that you might miss in another," said Craig Barnes, M.D., section head of pediatric radiology at Wake Forest Baptist's Brenner Children's Hospital. "It costs no more as relates to scan time or radiation exposure, and we believe it provides added value in diagnosis."

17 May 2005

Improvements in critical care decrease risk of post-injury multiple organ failure

Improvements in critical care and decreased use of blood transfusions over the course of the last decade are associated with decreases in the rate, severity and risk of death from post-injury multiple organ failure, according to a study in the May issue of Archives of Surgery.

16 May 2005

Exaggerated blood pressure reaction to mental stress predicts cardiovascular risk

When mental stress sparks a significant rise in blood pressure, it may be a sign of other existing cardiovascular risk factors, researchers reported today at the American Society of Hypertension’s Twentieth Annual Scientific Meeting.

16 May 2005

Distributing medications in specially designed blister packages rather than in bottles may increase the likelihood that medications will be taken properly

The study found that patients taking lisinopril – a medication used to treat chronic high blood pressure – were more likely to have their prescriptions refilled on time if the medication came in a blister package rather than as loose tablets in a bottle. In this case, the blister package clearly started the day on which to take each pill.

16 May 2005

Unsuspected protein CD147, regulates the production of plaque-forming peptides that are the defining feature of Alzheimer's

Researchers at the Department of Energy's Lawrence Berkeley National Laboratory have discovered an unsuspected subunit of the protein complex gamma-secretase, which plays a central role in Alzheimer's disease.

15 May 2005

New anticancer drug SU11248 shows continued response for patients with late-stage kidney cancer

Recent studies of a new anticancer drug show continued response for patients with late-stage kidney cancer. Robert Motzer, MD, attending physician at Memorial Sloan-Kettering Cancer Center (MSKCC), reported a response rate of 40 percent in patients with metastatic (advanced) renal cell (kidney) cancer who received SU11248 in second-line therapy.

15 May 2005

Research proves the dangers of salt

Sydney University scientists have proved that salt has a dangerous adrenalin-inducing effect on people suffering from high blood pressure, or 'hypertension'.

10 May 2005

Metabolic syndrome costing four times that for all other patients

It is well known that hypertension, diabetes, and obesity are each taking a toll on Americans' health, but according to a new analysis, metabolic syndrome, a condition characterized by a combination of these and/or other risk factors, is fast becoming one of the nation's costliest health concerns.

9 May 2005

Chronic kidney disease linked to a single gene mutation

New research in the US has found that a mutation in a single gene causes a form of chronic kidney disease.

5 May 2005

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Two infant boys whose bodies were overloaded with excess fluid have led UCSF pediatricians to the discovery of a new genetic disease. In the process, they have discovered a rare type of mutation where different substitutions in a single amino acid cause two different, opposite genetic disorders.

4 May 2005

Pharmacogenomics used to treat inherited kidney disorder of children

Mayo Clinic researchers have used pharmacogenomics to develop a test and treatment for an inherited kidney disorder that can cause organ failure in children and young adults.

4 May 2005

Specific variants of genes predict bleeding after heart surgery

Duke University Medical Center researchers have found that the presence of specific variants of genes that control clotting and the contractility, or "tone," of blood vessels can double the ability of physicians to predict those heart surgery patients at greatest risk of bleeding after surgery.

4 May 2005

Diabetes appears to rob women of usual advantage in heart disease risk

For men, a heart attack increases the risk of dying from coronary heart disease more than diabetes does, but for women, diabetes is sometimes the greater threat, according to a new study (PDF) in the May 3, 2005, issue of the Journal of the American College of Cardiology.

4 May 2005

Scientists dramatically slow organ transplant rejection

That's the promising implication of an animal study carried out by researchers at the University of Alabama at Birmingham (UAB) and the University of Florida (UF) published in today's (May 2) issue of Proceedings of the National Academy of Sciences.

3 May 2005

Age-related macular degeneration is triggered, possibly by an infection

Age-related macular degeneration, the leading cause of blindness in the elderly, occurs when a common inherited gene variation is triggered, possibly by an infection, according to a new study led by researchers at Columbia University Medical Center and the University of Iowa, with an international research team.

1 May 2005

Nephrology News and Research

Further Reading

Narcotic medications can safely and effectively ease severe, chronic pain in older people

Two out of three Americans with type-2 diabetes do not have their disease under control

Patients with type 2 diabetes who participate in group education programs require less medication

Nutritional composition of a mother’s breast milk may depend not just on her diet - but on her genes

Hypertension drug combination yields high rate of blood pressure control in hard-to-treat patients

Routinely reformatting computed tomography (CT) scans to view organs from several different directions may help radiologists improve diagnosis

Improvements in critical care decrease risk of post-injury multiple organ failure

Exaggerated blood pressure reaction to mental stress predicts cardiovascular risk

Distributing medications in specially designed blister packages rather than in bottles may increase the likelihood that medications will be taken properly

Unsuspected protein CD147, regulates the production of plaque-forming peptides that are the defining feature of Alzheimer's

New anticancer drug SU11248 shows continued response for patients with late-stage kidney cancer

Research proves the dangers of salt

Metabolic syndrome costing four times that for all other patients

Chronic kidney disease linked to a single gene mutation

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Pharmacogenomics used to treat inherited kidney disorder of children

Specific variants of genes predict bleeding after heart surgery

Diabetes appears to rob women of usual advantage in heart disease risk

Scientists dramatically slow organ transplant rejection

Age-related macular degeneration is triggered, possibly by an infection

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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