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CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

A team of researchers at Cold Spring Harbor Laboratory (CSHL) has identified a leukemia-specific stretch of DNA called an enhancer element that enables cancerous blood cells to proliferate in Acute Myeloid Leukemia (AML), a devastating cancer that is incurable in 70% of patients.

27 Nov 2013

Risk factors for Alzheimer's disease

Alzheimer's disease has joined cancer at the top of the list of feared diagnoses, and although Alzheimer's does have the potential to devastate millions of patients and families, there are reasons for hope - and possibly opportunities to reduce risk or alter the course of disease progression, according to Keith Black, MD, professor and chair of the Department of Neurosurgery at Cedars-Sinai.

26 Nov 2013

Researchers receive $2.5M grant to study telephone-based approach to improve diabetes treatment outcomes

More than 25 million Americans have diabetes, yet as many as 60 percent of type 2 diabetes patients do not follow treatment plans prescribed by their healthcare provider and about 50 percent fail to meet treatment recommendations for control of blood glucose levels.

26 Nov 2013

Childhood exercise help mitigate obesity due to prenatal exposure to high-fat diets

Rats whose mothers were fed a high-fat diet during pregnancy and nursing were able to stave off some of the detrimental health effects of obesity by exercising during their adolescence, new Johns Hopkins research shows.

26 Nov 2013

Researchers identify two gene mutations associated with increased risk of eating disorders

Eating disorders are disturbing and often-heartbreaking ailments that are relatively common, mostly among younger women.

25 Nov 2013

Research: Smallest parts of brain play crucial role in decision making

One of the smallest parts of the brain is getting a second look after new research suggests it plays a crucial role in decision making.

25 Nov 2013

EC approves INVOKANA (canagliflozin) medication for adults with type 2 diabetes mellitus

Janssen-Cilag International NV announced today that the European Commission has approved INVOKANA (canagliflozin) in the European Union for the treatment of adults with type 2 diabetes mellitus, to improve glycaemic control[1]. Canagliflozin is an oral, once-daily medication, which belongs to a new class of medications called sodium glucose co-transporter 2 (SGLT2) inhibitors.

23 Nov 2013

Study may shed light on neural regrowth in mammals after spinal cord injury

Fish, unlike humans, can regenerate nerve connections and recover normal mobility following an injury to their spinal cord. Now, University of Missouri researchers have discovered how the sea lamprey, an eel-like fish, regrows the neurons that comprise the long nerve "highways" that link the brain to the spinal cord.

22 Nov 2013

Scientists hope to find new treatments for traumatic brain injury

In the most wide-reaching project of its kind, scientists at the University of Texas Medical Branch are expanding their research on traumatic brain injury, examining its progressive, chronic effects on the body in hopes of treating its immediate and long-term consequences. The project is funded by a three-year, $9 million grant from The Moody Foundation of Galveston.

22 Nov 2013

New targeted treatments for autism may be possible

Finding major new clues to the origins of autism, a Yale-led team of researchers has pinpointed which cell types and regions of the developing human brain are affected by gene mutations linked to autism. They report their findings in the Nov. 21 issue of the journal Cell.

22 Nov 2013

Studies link hundreds of gene mutations in the brain to increased autism risk

Pity the poor autism researcher. Recent studies have linked hundreds of gene mutations scattered throughout the brain to increased autism risk. Where do you start?

22 Nov 2013

High knowledge about HIV and risky sexual activity does not make teens more likely to get tested for HIV

Having high knowledge about HIV and engaging in risky sexual activity do not make high-school-aged teens more likely to get tested for HIV. Those are the findings of a new study by researchers at Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University.

22 Nov 2013

MEMREHAB Trial shows significant effect for cognitive rehabilitation in MS

Kessler Foundation researchers published the results of the MEMREHAB Trial in Neurology, the medical journal of the American Academy of Neurology, providing the first Class I evidence for the efficacy of cognitive rehabilitation in multiple sclerosis. The article, Chiaravalloti N, Moore NB, Nikelshpur OM, DeLuca D: An RCT to treat learning impairment in MS. Neurology 2013(81), was released as an epub ahead of print on November 8

22 Nov 2013

Attractants prevent maturing nerve cells from migrating into brain

A vision is to implant nerve precursor cells in the diseased brains of patients with Parkinson's and Huntington's diseases, whereby these cells are to assume the function of the cells that have died off.

21 Nov 2013

Cedars-Sinai study presents new insights into mechanisms underlying the symptoms of autism

In what are believed to be the first studies of their kind, Cedars-Sinai researchers recording the real-time firing of individual nerve cells in the brain found that a specific type of neuron in a structure called the amygdala performed differently in people who suffer from autism spectrum disorder than in those who do not.

21 Nov 2013

Long-term cocaine abuse may be linked with deficits in parts of brain overseeing own behavior

New research from the Icahn School of Medicine at Mount Sinai reveals long-term cocaine abuse may be associated with deficits in parts of the brain involved in monitoring and overseeing one's own behavior.

21 Nov 2013

Zale Lipshy University Hospital receives 2013 Press Ganey Beacon of Excellence Award

Zale Lipshy University Hospital at UT Southwestern Medical Center received the 2013 Press Ganey Beacon of Excellence Award for patient satisfaction, one of only three academic medical centers in the nation and one of 26 health care facilities selected nationally to receive that distinction.

21 Nov 2013

Multiple sclerosis researchers receive NMSS drug development grant

A $500,000 drug development grant from the National Multiple Sclerosis Society was awarded to a partnership between a multiple sclerosis research team at the Icahn School of Medicine at Mount Sinai and Karyopharm Therapeutics Inc., a clinical stage pharmaceutical company. Dr. Patrizia Casaccia, MD, PhD, Professor in the Departments of Neuroscience and Genetics and Genomics, at Icahn School of Medicine at Mount Sinai, will be the academic lead.

21 Nov 2013

Enhancing the NMDA glutamate receptor causes antidepressant-like effects

Thirteen years ago, an article in this journal first reported that the anesthetic medication, ketamine, showed evidence of producing rapid antidepressant effects in depressed patients who had not responded to prior treatments. Ketamine works by blocking one of the targets for the neurotransmitter glutamate in the brain, the N-methyl-D-aspartate (NMDA) glutamate receptor.

20 Nov 2013

Nurse receives 2013 ARN Doctorate-Prepared Researcher Role Award at 39th Annual ARN Educational Conference

The Association of Rehabilitation Nurses (ARN) presented Kathleen Brewer-Smyth, PhD RN CRRN, with the 2013 ARN Doctorate-Prepared Researcher Role Award. Dr. Brewer-Smyth received her award at the 39th Annual ARN Educational Conference, held October 2-5 in Charlotte, NC.

20 Nov 2013

Neuroscience News and Research

CSHL identifies specific stretch of DNA that helps cancerous blood cells to proliferate in AML

Risk factors for Alzheimer's disease

Researchers receive $2.5M grant to study telephone-based approach to improve diabetes treatment outcomes

Childhood exercise help mitigate obesity due to prenatal exposure to high-fat diets

Researchers identify two gene mutations associated with increased risk of eating disorders

Research: Smallest parts of brain play crucial role in decision making

EC approves INVOKANA (canagliflozin) medication for adults with type 2 diabetes mellitus

Study may shed light on neural regrowth in mammals after spinal cord injury

Scientists hope to find new treatments for traumatic brain injury

New targeted treatments for autism may be possible

Studies link hundreds of gene mutations in the brain to increased autism risk

High knowledge about HIV and risky sexual activity does not make teens more likely to get tested for HIV

MEMREHAB Trial shows significant effect for cognitive rehabilitation in MS

Attractants prevent maturing nerve cells from migrating into brain

Cedars-Sinai study presents new insights into mechanisms underlying the symptoms of autism

Long-term cocaine abuse may be linked with deficits in parts of brain overseeing own behavior

Zale Lipshy University Hospital receives 2013 Press Ganey Beacon of Excellence Award

Multiple sclerosis researchers receive NMSS drug development grant

Enhancing the NMDA glutamate receptor causes antidepressant-like effects

Nurse receives 2013 ARN Doctorate-Prepared Researcher Role Award at 39th Annual ARN Educational Conference

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