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Irradiation of tumors with laser protons tested for the first time

Irradiation with fast protons is a more effective and less invasive cancer treatment than X-rays. However, modern proton therapy requires large particle accelerators, which has experts investigating alternative accelerator concepts, such as laser systems to accelerate protons.

14 Mar 2022

Researchers find unusual way of stabilizing cancer-suppressing protein

The p53 protein protects our cells from cancer and is an interesting target for cancer treatments. The problem is, however, that it breaks down rapidly in the cell. Researchers at Karolinska Institutet in Sweden have now found an unusual way of stabilizing the protein and making it more potent.

14 Mar 2022

New smartphone app can calculate users’ genetic risk for coronary artery disease

A Scripps Research team developed a smartphone app that can calculate users' genetic risk for coronary artery disease (CAD) - and found that users at high risk sought out appropriate medication after using the app.

14 Mar 2022

Novel nanocapsules offer solution for improving the efficacy of chemodynamic oncotherapy

In a paper published on Small recently, a collaborated research team led by Prof. WANG Hui from High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences reported the synthesis of hollow cuprous carbon (HCONC) by one-step hydrothermal method as well as their applications in efficient chemodynamic therapy.

14 Mar 2022

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

Researchers evaluated the effectiveness of isotretinoin (13-cis retinoic acid) in improving COVID-19 outcomes.

14 Mar 2022

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms.

14 Mar 2022

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

Researchers demonstrate enhanced loss-of-function editing of CRISPR/Cas9 in human cells.

14 Mar 2022

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

Researchers evaluated the survival benefit conferred by PLEX in patients with severe COVID-19 and cytokine-storm syndrome.

14 Mar 2022

AI companion tells stories to aid memory recollection, boost confidence in people with dementia

Researchers at the National Robotarium, hosted by Heriot-Watt University and the University of Edinburgh, are developing an artificial intelligence (AI) companion that will aid memory recollection, boost confidence and combat depression in people living with Alzheimer’s disease and other types of dementia.

14 Mar 2022

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Immune checkpoint blockade (ICB) inhibitors have transformed the treatment of cancer and have become the frontline therapy for a broad range of malignancies. It's because they work better than the previous standard of care.

11 Mar 2022

Mice study shows how to improve long-term effectiveness of TB vaccine

Briefly blocking a key molecule when administering the only approved vaccine for tuberculosis vastly improves long-term protection against the devastating disease in mice, researchers from Texas Biomedical Research Institute report this week in the Journal of Immunology.

11 Mar 2022

Lower, more frequent doses of nanomedicines may provide additional benefits for cancer patients

Tiny structures called nanoparticles can be used to carry substances to certain parts of the body - for example, to deliver a chemotherapy drug to a tumor.

11 Mar 2022

Meta-analysis finds intensified anticoagulation had no effect on short term mortality among hospitalized COVID-19 patients

A recent systematic review and meta-analysis evaluated the safety and efficacy of intensified anticoagulation therapy in COVID-19 patients.

11 Mar 2022

Novel genetic relationships with severe SARS-CoV-2

Researchers discovered multiple novel genetic processes underpinning severe COVID-19 using genome-wide association studies and meta-analyses.

11 Mar 2022

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Antibiotic-resistant bacterial infections are difficult to treat and cause more than a million annual deaths worldwide, especially in hospitalized patients with pneumonia, bloodstream infections, urinary tract infections, or abdominal infections.

11 Mar 2022

Ribociclib plus endocrine therapy offers survival benefit for postmenopausal patients with metastatic breast cancer

A study led by researchers from The University of Texas MD Anderson Cancer Center showed a significant overall survival benefit with ribociclib plus endocrine therapy for postmenopausal patients with hormone receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer.

10 Mar 2022

Most cancer patients develop antibodies after receiving COVID-19 vaccine, study shows

Cancer patients who have compromised immune systems due to their disease or therapy remain at high risk for COVID-19 infection.

10 Mar 2022

Researchers identify motor neuron toxin associated with ALS

An international team of investigators has discovered that an inorganic polyphosphate released by nerve cells known as astrocytes in people with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) contributes to the motor neuron death that is the signature of these diseases.

10 Mar 2022

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

10 Mar 2022

Damage to the inner ear system linked to fall risk among Alzheimer’s patients

A Johns Hopkins Medicine study of about 50 people with Alzheimer's disease has added to evidence that damage to the inner ear system that controls balance is a major factor in patients' well-documented higher risk of falling.

10 Mar 2022

Therapy News and Research

Irradiation of tumors with laser protons tested for the first time

Researchers find unusual way of stabilizing cancer-suppressing protein

New smartphone app can calculate users’ genetic risk for coronary artery disease

Novel nanocapsules offer solution for improving the efficacy of chemodynamic oncotherapy

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

AI companion tells stories to aid memory recollection, boost confidence in people with dementia

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Mice study shows how to improve long-term effectiveness of TB vaccine

Lower, more frequent doses of nanomedicines may provide additional benefits for cancer patients

Meta-analysis finds intensified anticoagulation had no effect on short term mortality among hospitalized COVID-19 patients

Novel genetic relationships with severe SARS-CoV-2

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Ribociclib plus endocrine therapy offers survival benefit for postmenopausal patients with metastatic breast cancer

Most cancer patients develop antibodies after receiving COVID-19 vaccine, study shows

Researchers identify motor neuron toxin associated with ALS

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

Damage to the inner ear system linked to fall risk among Alzheimer’s patients

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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