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QUT researchers identify drug that could reverse brain deficits caused by alcohol

Queensland University of Technology researchers have identified a drug that could potentially help our brains reboot and reverse the damaging impacts of heavy alcohol consumption on regeneration of brain cells.

8 Feb 2018

Researchers describe human blood-nerve barrier transcriptome for the first time

Human peripheral nerves -- all the nerves outside of the central nervous system -- are protected by the blood-nerve barrier. This is a tight covering of endothelial cells that maintains the microenvironment within the nerves by restricting the amounts or types of water, ions, solutes and nutrients that can reach the axons, or electric cables within the nerves, from the blood circulation system.

8 Feb 2018

Symptoms of alcoholism affect prescription drug adherence to treat disease

Symptoms of alcoholism make it more difficult for some people to regularly take the prescription drug naltrexone, which could help treat their disease, a researcher at Oregon State University has found.

8 Feb 2018

Vapors could elevate pneumonia risk, study states

A new study suggests inhaling vapor from e-cigarettes could cause pneumonia-causing bacteria to attach to the cells that line airways.

8 Feb 2018

Researchers identify presence of ER gene fusion proteins in treatment-resistant breast cancer

At Magee-Womens Research Institute and UPMC Hillman Cancer Center, a large team of clinical and laboratory researchers dedicated to understanding treatment resistance in the most common form of breast cancer have identified a new genetic change in the estrogen receptor that contributes to therapy resistance.

7 Feb 2018

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic.

7 Feb 2018

Study adds more evidence that intestinal microbiome plays substantial role in obesity

A new Johns Hopkins study of mice with the rodent equivalent of metabolic syndrome has added to evidence that the intestinal microbiome - a "garden" of bacterial, viral and fungal genes - plays a substantial role in the development of obesity and insulin resistance in mammals, including humans.

6 Feb 2018

Microscope technology reveals full-length serotonin receptor structure for first time

A team of researchers from Case Western Reserve University School of Medicine have used Nobel prize-winning microscope technology to see full-length serotonin receptors for the first time.

6 Feb 2018

Health indicators for children born to breast cancer survivors may depend on cancer type

For breast cancer survivors, the risk of giving birth prematurely, and for other health concerns for their newborns, may depend on the type of breast cancer they had, according to a study from University of North Carolina Lineberger Comprehensive Cancer Center researchers.

6 Feb 2018

Research uncovers key process that enables Ebola virus to infect host cells

Researchers have identified a key process that enables the Ebola virus to infect host cells, providing a novel target for developing antiviral drugs.

6 Feb 2018

Researchers receive major boost to explore long-standing paradigm in endocrinology

A team of researchers at the University of California, Riverside, seeking to upend a long-held theory explaining how hormones freely enter and exit cells, has received a major boost in the form of a $1 million award from the W. M. Keck Foundation.

5 Feb 2018

Researchers use innovative method to screen kinases for cancer drug's effectiveness

In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude from cell surfaces like antennae and can activate cancer-related pathways in virtually all types of cancer when signaling molecules bind with them.

5 Feb 2018

Scientists develop immune-stimulating injections against cancer

A team of researchers have developed two immune-stimulating injections, that removed all traces of cancer when injected directly into solid mouse tumors.

2 Feb 2018

Fight for Sight awards new grants for 13 vital eye research projects

Fight for Sight, the leading eye research charity, has awarded grants totaling over £180,000 for thirteen vital research projects in partnership with nine different organizations.

2 Feb 2018

New modular platform offers robust biological approach that targets endless number of diseases

The biological complexity of cancer and other diseases demands a more formidable arsenal of therapies than currently available. Most therapeutic approaches ignore the dynamic molecular network of genes, targeting instead only very few selected disease-related genes.

1 Feb 2018

New clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy

An international group of clinicians and scientists representing the Clinical Pharmacogenetics Implementation Consortium published the first-ever clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy in Clinical Pharmacology and Therapeutics.

1 Feb 2018

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

A historic study involving researchers from UT Southwestern's Harold C. Simmons Comprehensive Cancer Center demonstrates the effectiveness of CAR-T therapy, which uses genetically modified immune cells to treat acute lymphoblastic leukemia (ALL) in children and young adults. The research appears in the New England Journal of Medicine.

1 Feb 2018

Platelets play more important role in the immune system than previously thought

Platelets play a much more important role in our immune system than previously thought, according to a study published by researchers from Université Laval and Centre hospitalier universitaire de Québec Research Center.

1 Feb 2018

Scientists decipher molecular structure of antipsychotic docked in its key receptor

Antipsychotic drugs - which transformed mental health care following their chance discovery in the mid-20th Century - may finally be poised for a long-overdue makeover incorporating structure-based design.

1 Feb 2018

Neuroscientists identify 'anxiety cells' in the brain's hippocampus

Do your palms sweat when you walk down a poorly lit street at night? That feeling may be traced to the firing of newly identified "anxiety" cells deep inside your brain, according to new research from neuroscientists at Columbia University Irving Medical Center and the University of California, San Francisco.

31 Jan 2018

Receptor News and Research

QUT researchers identify drug that could reverse brain deficits caused by alcohol

Researchers describe human blood-nerve barrier transcriptome for the first time

Symptoms of alcoholism affect prescription drug adherence to treat disease

Vapors could elevate pneumonia risk, study states

Researchers identify presence of ER gene fusion proteins in treatment-resistant breast cancer

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

Study adds more evidence that intestinal microbiome plays substantial role in obesity

Microscope technology reveals full-length serotonin receptor structure for first time

Health indicators for children born to breast cancer survivors may depend on cancer type

Research uncovers key process that enables Ebola virus to infect host cells

Researchers receive major boost to explore long-standing paradigm in endocrinology

Researchers use innovative method to screen kinases for cancer drug's effectiveness

Scientists develop immune-stimulating injections against cancer

Fight for Sight awards new grants for 13 vital eye research projects

New modular platform offers robust biological approach that targets endless number of diseases

New clinical practice guideline for using CYP2D6 genotype to guide tamoxifen therapy

Historic study involving Simmons Cancer Center shows effectiveness of CAR-T therapy

Platelets play more important role in the immune system than previously thought

Scientists decipher molecular structure of antipsychotic docked in its key receptor

Neuroscientists identify 'anxiety cells' in the brain's hippocampus

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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