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Immunoregulatory genes modulate otitis media risk

Variation in genes involved in immunity influences children’s susceptibility to developing otitis media, according to research by a US team.

28 Apr 2014

Forest Laboratories enters into definitive agreement to acquire Furiex

Forest Laboratories, Inc. nd Furiex Pharmaceuticals, Inc. today announced that Forest has entered into a definitive agreement to acquire Furiex, a drug development collaboration company, for $95 per share, or approximately $1.1 billion in cash, and up to $30 per share (approximately $360 million in aggregate) in a Contingent Value Right (CVR) that may be payable based on the status of eluxadoline, Furiex's lead product, as a controlled drug following approval.

28 Apr 2014

Researchers identify genetic factors that contribute to ADHD in humans

The 60 trillion cells that comprise our bodies communicate constantly. Information travels when chemical compounds released by some cells are received by receptors in the membrane of another cell.

26 Apr 2014

New data from EMD Serono's multiple sclerosis portfolio to be presented at the 66th AAN Annual Meeting

EMD Serono, Inc., a subsidiary of Merck KGaA, Darmstadt, Germany, announced today that new data from the company's multiple sclerosis (MS) portfolio will be presented at the American Academy of Neurology's 66th Annual Meeting, taking place from April 26 – May 3, in Philadelphia, PA.

26 Apr 2014

UTMB awarded $6.6 million grant to establish Translational Addiction Sciences Center

The National Institute on Drug Abuse has awarded a five-year, $6.6 million grant to the University of Texas Medical Branch at Galveston to establish the Translational Addiction Sciences Center. The center will investigate the mechanisms underlying addiction with the goal of discovering and validating novel treatment options.

26 Apr 2014

UB research finds novel compound for treating cocaine addiction

A novel compound that targets an important brain receptor has a dramatic effect against a host of cocaine addiction behaviors, including relapse behavior, a University at Buffalo animal study has found.

25 Apr 2014

Meta-analysis links signalling pathways to bipolar disorder

A meta-analysis of genome-wide association studies has identified six biological pathways that may be involved in the genetic predisposition to develop bipolar disorder.

23 Apr 2014

TSRI scientists identify protein complex that plays critical role in learning and memory formation

Scientists from the Florida campus of The Scripps Research Institute have identified a protein complex that plays a critical but previously unknown role in learning and memory formation.

23 Apr 2014

Kala Pharmaceuticals completes $22.5 million Series B financing

Kala Pharmaceuticals, Inc., a leading developer of innovative ophthalmic products based on the company's proprietary Mucus Penetrating Particle (MPP) platform technology, today announced it has completed a $22.5 million Series B financing.

23 Apr 2014

Researchers develop first size-based form of chromatography using nanodot technology

Using nanodot technology, Berkeley Lab researchers have demonstrated the first size-based form of chromatography that can be used to study the membranes of living cells.

23 Apr 2014

Bile acids could be a new target for treating obesity and diabetes, say researchers

Bariatric surgery has positive effects not only on weight loss but also on diabetes and heart disease. Researchers at the Sahlgrenska Academy and University of Cincinnati have shown that the health benefits are not caused by a reduction in the stomach size but by increased levels of bile acids in the blood.

23 Apr 2014

Studies identify 2 genes highly associated with IBD

Inflammatory Bowel Disease (IBD), a group of chronic inflammatory disorders of the intestine that result in painful and debilitating complications, affects over 1.4 million people in the U.S., and while there are treatments to reduce inflammation for patients, there is no cure.

23 Apr 2014

Drug used to treat hypertension prevents post-traumatic epilepsy in rodent model

Between 10 and 20 percent of all cases of epilepsy result from severe head injury, but a new drug promises to prevent post-traumatic seizures and may forestall further brain damage caused by seizures in those who already have epilepsy.

23 Apr 2014

FDA approves Cyramza to treat patients with advanced stomach cancer

Based on results of a clinical trial led by Dana-Farber Cancer Institute scientists, the U.S. Food and Drug Administration (FDA) approved a molecularly targeted drug as second-line treatment in advanced stomach cancer that has progressed after standard chemotherapy has failed.

22 Apr 2014

Scientists examine Gpr109a receptor to find potential treatment for diabetic retinopathy

Like a daily pill to lower cholesterol can reduce heart attack and stroke risk, an easy-to-use agent that reduces eye inflammation could help save the vision of diabetics, scientists say.

22 Apr 2014

New genetic evidence strengthens link between role of dietary fats with colon cancer progression

Scientists have shown new genetic evidence that could strengthen the link between the role of dietary fats with colon cancer progression.

22 Apr 2014

FDA approves molecularly targeted drug as second-line treatment for advanced stomach cancer

Based on results of a clinical trial led by Dana-Farber Cancer Institute scientists, the U.S. Food and Drug Administration approved a molecularly targeted drug as second-line treatment in advanced stomach cancer that has progressed after standard chemotherapy has failed.

22 Apr 2014

Can-Fite BioPharma signs agreement with Smart Assays to develop A3AR predictive biomarker kit

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced today it has signed an agreement with Smart Assays to develop a commercial biomarker blood test kit for the A3 adenosine receptor (A3AR).

21 Apr 2014

Research: Drugs used to treat lung, breast and pancreatic cancers promote drug-resistance, spur tumor growth

Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.

21 Apr 2014

Northwestern Medicine study provides new insights on tissue scarring in scleroderma

A discovery by Northwestern Medicine scientists could lead to potential new treatments for breaking the cycle of tissue scarring in people with scleroderma.

21 Apr 2014

Receptor News and Research

Immunoregulatory genes modulate otitis media risk

Forest Laboratories enters into definitive agreement to acquire Furiex

Researchers identify genetic factors that contribute to ADHD in humans

New data from EMD Serono's multiple sclerosis portfolio to be presented at the 66th AAN Annual Meeting

UTMB awarded $6.6 million grant to establish Translational Addiction Sciences Center

UB research finds novel compound for treating cocaine addiction

Meta-analysis links signalling pathways to bipolar disorder

TSRI scientists identify protein complex that plays critical role in learning and memory formation

Kala Pharmaceuticals completes $22.5 million Series B financing

Researchers develop first size-based form of chromatography using nanodot technology

Bile acids could be a new target for treating obesity and diabetes, say researchers

Studies identify 2 genes highly associated with IBD

Drug used to treat hypertension prevents post-traumatic epilepsy in rodent model

FDA approves Cyramza to treat patients with advanced stomach cancer

Scientists examine Gpr109a receptor to find potential treatment for diabetic retinopathy

New genetic evidence strengthens link between role of dietary fats with colon cancer progression

FDA approves molecularly targeted drug as second-line treatment for advanced stomach cancer

Can-Fite BioPharma signs agreement with Smart Assays to develop A3AR predictive biomarker kit

Research: Drugs used to treat lung, breast and pancreatic cancers promote drug-resistance, spur tumor growth

Northwestern Medicine study provides new insights on tissue scarring in scleroderma

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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