Inflammation News and Research

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Mitochondrial dysfunction may underlie prolonged muscle weakness after sepsis

Damage to energy-producing mitochondria may underlie prolonged muscle weakness following a sepsis-like condition in mice, according to a new study published today in eLife.

10 Dec 2019

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Researchers demonstrated that Lactobacillus rhamnosus can dose-dependently reestablish a balanced intestinal microbiome and counter the liver-damaging effects of alcohol consumption in mice to reverse the results of chronic alcohol-induced liver injury.

9 Dec 2019

Dead probiotic reduces age-related leaky gut in older mice, study finds

Scientists at Wake Forest School of Medicine have identified a dead probiotic that reduces age-related leaky gut in older mice. The study is published in the journal GeroScience.

9 Dec 2019

New nanoparticle innovation detects vascular calcification in atherosclerosis

Heart disease and stroke are the world's two most deadly diseases, causing over 15 million deaths in 2016 according to the World Health Organization.

9 Dec 2019

Research shows how high levels of blood fat induce inflammation and organ damage

Viral and bacterial infections are not the only causes of inflammation of body tissue. It has been known for some time that certain fat molecules in our bloodstream can also trigger an inflammatory response.

9 Dec 2019

Award to help advance development of diagnostic test for necrotizing enterocolitis

The Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health has awarded Chosen Diagnostics Inc, a spin-out company, a $299,641 Phase I Small Business Technology Transfer award.

9 Dec 2019

Exercise improves key measures of cardiovascular health

Eight months of daily, afterschool physical activity in previously inactive 8- to 11-year-olds with obesity and overweight improved key measures of their cardiovascular health like good cholesterol levels, aerobic fitness and percent body fat, but didn't improve others like arterial stiffness, an early indicator of cardiovascular risk, investigators report.

9 Dec 2019

Identifying the type of pain in adults with sickle cell disease may help improve treatment

Identifying the type of pain an adult with sickle cell disease experiences may be useful in improving treatment, according to a new study by researchers at Yale Cancer Center and Smilow Cancer Hospital.

8 Dec 2019

New startup aims to prevent reperfusion-related organ damage after liver transplant

Roughly 65 years ago, the first human organ transplant was successfully performed. A decade later, heart and liver transplants became possible. Now, a startup founded by researchers from the Medical University of South Carolina and elsewhere hopes to bring about the next major breakthrough.

8 Dec 2019

The role of adenosine in neurodegeneration and brain regeneration

The role of adenosine in neurodegeneration and neuroregeneration has led to growing attention on adenosine receptors as potential drug targets in a range of brain disorders, including neuroregenerative therapy and treatment for amyotrophyic lateral sclerosis.

8 Dec 2019

Genetically engineered living hydrogel material facilitates intestinal wound healing

About 1.6 million people in the US alone currently have lifelong and incurable Inflammatory Bowel Disease (IBD) including Crohn's disease and ulcerative colitis, and 70,000 new cases are diagnosed in the USA each year.

6 Dec 2019

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Patients with nonalcoholic steatohepatitis, a chronic liver disease and a leading cause for liver transplantation in the U.S., currently lack an approved drug therapy, but this may soon change.

6 Dec 2019

Mologic starts major clinical trial to validate point-of-care COPD exacerbation alert system

Mologic Ltd, a leading developer of lateral flow and rapid diagnostic technologies, today announced that it has started a major clinical trial to validate the Company’s urine-based multi-biomarker self-test, Headstart, for the early detection of exacerbations in patients living with moderate to severe Chronic Obstructive Pulmonary Disease .

6 Dec 2019

Perinatal maternal antibiotic exposure may impair lung development in premature infants

New research in mice suggests that exposure to antibiotics before birth may impair lung development in premature infants. The study, the first to explore the gut-lung axis in prematurity, is published ahead of print in the American Journal of Physiology—Lung Cellular and Molecular Physiology and was chosen as an APSselect article for December.

5 Dec 2019

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.

5 Dec 2019

NeutroCure project aims to cure inflammatory disease with neutrophils

Curing disease with neutrophils; this is the goal of the NeutroCure project. How will that work? "Neutrophils have a yin yang character," explained Andrés Hidalgo, whose team at the Centro Nacional de Investigaciones Cardiovasculares is one of six member groups participating in this project coordinated by Andriy Mokhir Friedrich from Alexander University, Germany.

5 Dec 2019

Inflammation News and Research

Mitochondrial dysfunction may underlie prolonged muscle weakness after sepsis

Lactobacillus balances intestinal microbiome and ameliorates chronic alcohol-induced liver injury

Dead probiotic reduces age-related leaky gut in older mice, study finds

New nanoparticle innovation detects vascular calcification in atherosclerosis

Research shows how high levels of blood fat induce inflammation and organ damage

Award to help advance development of diagnostic test for necrotizing enterocolitis

Exercise improves key measures of cardiovascular health

Identifying the type of pain in adults with sickle cell disease may help improve treatment

New startup aims to prevent reperfusion-related organ damage after liver transplant

The role of adenosine in neurodegeneration and brain regeneration

Genetically engineered living hydrogel material facilitates intestinal wound healing

Clinical trial demonstrates safety and effectiveness of oral drug to treat NASH

Mologic starts major clinical trial to validate point-of-care COPD exacerbation alert system

Perinatal maternal antibiotic exposure may impair lung development in premature infants

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

NeutroCure project aims to cure inflammatory disease with neutrophils

Anti-hepatitis treatment also helps improve later complications

A woman has developed rare form of lung metal-scarring from vaping

CDC cautions people to avoid e-cigarette products

ADDF announces new awards through its Diagnostics Accelerator initiative

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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