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SARS-CoV-2 infection and reinfection in farmed mink

A new study finds that farmed mink acquire SARS-CoV-2 infection, freely transmit it among themselves, and were reinfected, despite being seropositive.

18 Nov 2021

Scientists discover the genes used by bacteria to live within complex communities

Scientists from the Quadram Institute at the Norwich Research Park have made an important discovery into the workings of bacterial communities.

18 Nov 2021

Blood proteomic survey in undiagnosed population with COVID-19

In this study, scientists have profiled 276 circulating proteins that are associated with cardiovascular and metabolic functions.

18 Nov 2021

The antiviral function of BET protein against SARS-CoV-2 infection

Considering the past shreds of evidence on BRD2 and BRD4 associated with viral infections, researchers have recently evaluated the function of all relevant BET proteins during COVID-19 infection.

17 Nov 2021

Researchers identify compounds that tackle fungal infections in a new way

Current medications aren't particularly effective against fungi. The situation is becoming more challenging because these organisms are developing resistance to antimicrobial treatments, just as bacteria are.

17 Nov 2021

Northwestern awarded grant to advance equity in biomedical sciences

Northwestern University Feinberg School of Medicine has been awarded a grant from the Walder Foundation via the COVID-19 Fund to Retain Clinical Scientists (FRCS) competition, designed to support policies and practices at U.S. medical schools to advance research productivity and retain early-career clinician investigators experiencing family caregiving challenges due to the COVID-19 pandemic.

17 Nov 2021

Study uncovers the herpes virus' strategy for infecting the nervous system

Herpes type 1 is sealed with a kiss for a lifetime. More than half of U.S. adults are carriers of HSV1 (herpes simplex virus type 1) which hibernates in the peripheral nervous system and can never be eradicated.

17 Nov 2021

Researchers identify never-before-defined subtypes of a blood cancer

Mount Sinai researchers have developed a new model that uses DNA and RNA sequencing data from hundreds of patients to identify specific genes and genetic alterations responsible for never-before-defined subtypes of a blood cancer called multiple myeloma.

17 Nov 2021

Study may help predict genomic changes that may happen in advanced cancers based on therapy

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Scientists predict structures of eukaryotic protein complexes using AI

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

'Brain age' mostly relates to early life influences

Researchers in brain science and aging are very interested in measuring the health of a brain using a single observation. The most popular way to measure it is through a method called "brain age".

16 Nov 2021

Young adults with cancer may require different treatments than older patients

Not all tumors are alike. Young adults who are diagnosed with skin, colon, and other cancer types may require different treatments than older patients receive.

16 Nov 2021

Scientists identify new gene that contributes to type 1 diabetes progression

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

16 Nov 2021

New research finds disturbing lack of crucial blood cancer medication

New research in the November 2021 issue of JNCCN - Journal of the National Comprehensive Cancer Network finds fewer than one-third of hospitals had immediate availability of a crucial blood cancer medication called all-trans retinoic acid (ATRA).

16 Nov 2021

Two genetic risk variants in Black individuals may exacerbate sepsis and COVID-19 severity

Two genetic risk variants that are carried by nearly 40 percent of Black individuals may exacerbate the severity of both sepsis and COVID-19, a team of researchers from the University of Pennsylvania's Perelman School of Medicine have found.

16 Nov 2021

A therapeutic interfering particle for SARS-CoV-2

Researchers report their attempt to engineer TIPs that can conditionally replicate with SARS-CoV-2, inhibit viral replication 10–100 fold, and exhibit R0>1.

16 Nov 2021

Researchers develop a highly efficient method to generate immune cells for cancer therapies

A Ludwig Cancer Research study has devised a highly efficient method to generate large numbers of immune cells specifically engineered to recognize neoantigens - small fragments of randomly mutated proteins that are typically unique to a patient's cancer - and destroy the tumors that express them.

15 Nov 2021

Rapid thermal cycling approach for the detection of SARS-CoV-2

Researchers develop an ultrafast detection method for SARS-CoV-2 by direct RT-PCR without RNA extraction that is suitable for large-scale use.

15 Nov 2021

Machine learning analysis of long non-coding RNAs reveals new prognostic cancer biomarkers

A new batch of prognostic cancer biomarkers have been discovered in an area where few have gone looking before. Researchers have unveiled a catalogue of 166 prognostic biomarkers, generated by analyzing long non-coding RNAs (lncRNAs) – which are understudied in cancer research.

15 Nov 2021