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Penn Medicine receives $12.3 million NIH grant to study FLASH radiotherapy for cancer

With more than $12 million in new funding from the National Institutes of Health, the Abramson Cancer Center at the University of Pennsylvania will build on its preclinical research of an emerging form of radiation that provides ultra-fast doses - of under a second, compared to several minutes with conventional radiation - and shows promise of greater protection of normal tissue, thereby minimizing toxic effects to the body.

1 Mar 2022

AI and machine learning could improve cancer diagnosis through biomarker discovery

Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have transformed many industries and areas of science.

1 Mar 2022

Using AI to detect antibiotic resistance

In this interview, we speak to Professor Karsten Borgwardt and Professor Adrian Egli about their latest research that used AI to predict antibiotic resistance.

1 Mar 2022

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

In a new study, researchers evaluated the immune responses induced by the mRNA-based SARS-CoV-2 vaccination against SARS-CoV-2 variants in multiple myeloma patients.

1 Mar 2022

A dog day at the dentist’s: North Carolina regulates pups in dentistry

The first time 11-year-old Levi McAllister had a tooth pulled, he screamed, kicked, and struggled so much that his mom had to hold him down.

1 Mar 2022

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

In a recent study posted to the bioRxiv* preprint server, researchers demonstrated the potent neutralizing ability of a polyclonal equine antibody (Ab), FBR-002, against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs), including Omicron.

28 Feb 2022

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Melanoma patients receiving therapy that helps their immune system kill cancer cells respond to treatment differently depending on the types of microbes in their gut, and new research suggests the microorganisms hindering therapy have more influence than the beneficial ones.

28 Feb 2022

Study compares heterologous and homologous third vaccination in kidney transplant recipients

A new study assesses the comparative neutralizing antibody level elicited by three mRNA vaccine doses to a heterologous COVID-19 vaccine regimen.

28 Feb 2022

Researchers report a new, more efficient way to grow breast cancer models

For years, researchers at Huntsman Cancer Institute at the University of Utah have honed a process of developing breast cancer models using tumors donated by breast cancer patients, which they then implant into mice as a way to study the tumor's behavior.

28 Feb 2022

Antibiotic stewardship programs help long-term care facilities to reduce unnecessary antibiotic use

In early 2021, researchers at Johns Hopkins Medicine and NORC at the University of Chicago showed that the Agency for Healthcare Research and Quality (AHRQ) Safety Program for Improving Antibiotic Use — a comprehensive system they developed to assist health care institutions with establishing and operating antibiotic stewardship programs (ASPs) — successfully helped more than 400 U.S. hospitals ensure that patients only received antibiotics when needed, and then, only in the correct amounts and for the prescribed dosage period.

28 Feb 2022

Outpatient antibiotic treatment for infective endocarditis improves outcomes, reduces costs

A new modeling study suggests that when patients who inject opioids continue an antibiotic treatment for infective endocarditis outside of the hospital, they experienced better long-term health outcomes than patients who receive the standard four to six weeks of inpatient, intravenous antibiotic therapy.

28 Feb 2022

Understanding the gut microbiome could help personalize immunotherapy for melanoma

The largest study to date has confirmed the link between the gut microbiome and the response to cancer immunotherapy therapy for melanoma.

28 Feb 2022

Study shows the impact of gender-affirming hormone therapy on epigenetic signature of genes

Gender-affirming hormone therapy could influence the way a person's genes are turned on or off, according to a new study.

28 Feb 2022

Exercise may help reduce the risk of blood clots in patients with aggressive form of NAFLD

Exercise may help certain patients with nonalcoholic fatty liver disease (NAFLD) reduce their risk of developing blood clots, according to a new study by Penn State College of Medicine researchers.

28 Feb 2022

Researchers develop new precision medicine technology for cancer immunotherapy

In recent years, great advances have been made in the development of new successful immunotherapies to treat cancer. CAR T-cell therapy and antibody treatments are two types of targeted immunotherapies that have revolutionized areas of cancer care.

28 Feb 2022

ESMO announces a new series of resources to guide physicians in oncological practice

ESMO, the leading professional organization for medical oncology, announces a new series of resources designed to guide physicians in areas of oncological practice not covered by guidelines, where current evidence is insufficient to evenly inform clinical decision-making.

28 Feb 2022

Antibiotics provide no benefit in preventing recurrent wheezing in infants hospitalized with RSV

Antibiotics provide no benefit in preventing future recurrent wheezing in babies hospitalized with respiratory syncytial virus (RSV), according to a new study led by Washington University School of Medicine in St. Louis. And there is some evidence that antibiotics may make wheezing worse.

27 Feb 2022

New dialysis system shows ability to make sterile, medical grade water at the point-of-care

Findings from preliminary tests of a new dialysis system have confirmed its ability to make sterile, medical grade water to provide an affordable, accessible home-based treatment option for patients with kidney failure.

27 Feb 2022

Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients

Peanut allergies are hard to treat and can cause fatal or near-fatal anaphylactic reactions. People usually don't outgrow peanut allergy, requiring lifelong scrutiny of food labels to avoid even small traces of peanut.

27 Feb 2022

Harvard’s new kidney engineering technology licensed to San Diego-based Trestle Biotherapeutics

A newly launched startup is building upon innovations developed over several years at the Wyss Institute for Biologically Inspired Engineering at Harvard University, Harvard John A. Paulson School of Engineering & Applied Sciences (SEAS), and Brigham and Women’s Hospital (Brigham) to engineer functional kidney tissue for renal repair and replacement therapy.

25 Feb 2022

Therapy News and Research

Penn Medicine receives $12.3 million NIH grant to study FLASH radiotherapy for cancer

AI and machine learning could improve cancer diagnosis through biomarker discovery

Using AI to detect antibiotic resistance

Effect of mRNA-based COVID-19 vaccination in multiple myeloma patients

A dog day at the dentist’s: North Carolina regulates pups in dentistry

Encouraging in vitro results with SARS-CoV-2-spike-specific polyclonal antibody fragments

Microorganisms hindering cancer therapy have more influence than the beneficial ones, study says

Study compares heterologous and homologous third vaccination in kidney transplant recipients

Researchers report a new, more efficient way to grow breast cancer models

Antibiotic stewardship programs help long-term care facilities to reduce unnecessary antibiotic use

Outpatient antibiotic treatment for infective endocarditis improves outcomes, reduces costs

Understanding the gut microbiome could help personalize immunotherapy for melanoma

Study shows the impact of gender-affirming hormone therapy on epigenetic signature of genes

Exercise may help reduce the risk of blood clots in patients with aggressive form of NAFLD

Researchers develop new precision medicine technology for cancer immunotherapy

ESMO announces a new series of resources to guide physicians in oncological practice

Antibiotics provide no benefit in preventing recurrent wheezing in infants hospitalized with RSV

New dialysis system shows ability to make sterile, medical grade water at the point-of-care

Clinical trial shows encouraging results with fecal microbiota transplants for peanut-allergic patients

Harvard’s new kidney engineering technology licensed to San Diego-based Trestle Biotherapeutics

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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