Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

A gallery of highly-specific, gene and protein “mug shots” of cancer types would be a powerful for oncologists

Doctors would like to diagnose malignancies rapidly by matching them with highly-specific genetic “mug shots” based on the presence of characteristic mRNAs or proteins. This kind of specificity would facilitate screening and early detection, and would potentially allow targeted treatments specific to each type of cancer

4 Dec 2004

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Specific variants in genes that encode proteins regulating inflammation may hold a key to explaining a host of disease processes known to cause increased risk of illness and death among African Americans, according to a study from the University of Pittsburgh's Graduate School of Public Health (GSPH).

1 Dec 2004

Key molecule helps identify renal cell carcinoma

Mayo Clinic researchers have discovered a key molecule that lets doctors identify one of the most aggressive types of kidney cancer. Patients with renal cell carcinoma who have higher levels of a molecule known as B7-H1 in their tumors are nearly five times more likely to die from the disease than patients with low levels or an absence of the molecule.

30 Nov 2004

Type 1 diabetes could be prevented by a new nasal insulin vaccine

A world-leading medical trial conducted in Melbourne suggests that the onset of type 1 diabetes could be prevented in many at-risk people by a new nasal insulin vaccine.

29 Nov 2004

Scientists have induced human insulin-producing cells of the pancreas to revert to islet precursor cells

Scientists at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) have induced human insulin-producing cells of the pancreas to revert to islet precursor cells.

29 Nov 2004

Bypass surgery on a beating heart is an excellent option for many patients with blocked heart arteries

Bypass surgery on a beating heart is an excellent option for many patients with blocked heart arteries, according to a study in Circulation: Journal of the American Heart Association.

24 Nov 2004

Researchers have found that a blood-reduction program in cardiac surgery results in a reduced need for transfusions

Researchers at Virginia Commonwealth University’s Medical Center have found that a blood-reduction program in cardiac surgery is resulting in a reduced need for transfusions without compromising patients’ recoveries.

23 Nov 2004

Carbon coatings to prevent bacteria collecting on indwelling catheters

This team of physicists have coated catheters and ureter stents with an extremely thin layer of diamond-like carbon. DLC-coated surfaces do not react chemically with their environment; they are hardwearing, can be sterilised and reduce friction.

18 Nov 2004

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Generic antipsychotic drugs can protect brain cells from a virus that causes a fatal nervous system disorder, according to research conducted at Brown University and Case Western Reserve University.

18 Nov 2004

Sit down rounds improve outcomes for kidney dialysis patients

"Sit-down" medical rounds, during which a health care team meets to review a patient's medical record and discuss short- and long-term needs, are associated with better outcomes for kidney dialysis patients, a Johns Hopkins-directed study has found.

17 Nov 2004

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Remember when Grandma used to say, "don’t go out in the cold; you’ll get sick”? It turns out that she was right for a small number of people who have a condition called familial cold autoinflammatory syndrome (FCAS)

16 Nov 2004

Fluorescent protein tool may speed identification of molecular changes that reveal cells' inner workings

Scientists at Johns Hopkins and the University of Texas Medical Branch have created a new tool that easily reveals when and where a key cellular signal is active.

16 Nov 2004

Too much vitamin supplementation could be harmful

Daily vitamin E doses of 400 international units (IU) or more can increase the risk of death and should be avoided, researchers reported at the American Heart Association’s Scientific Sessions 2004.

11 Nov 2004

Lorus Therapeutics allowed Canadian patent to protect anticancer drugs

Lorus Therapeutics today announced that its wholly owned subsidiary, GeneSense Technologies Inc., has been allowed a patent by the Canadian Patent Office entitled "Antitumor Antisense Sequences Directed Against R1 and R2 Components of Ribonucleotide Reductase."

10 Nov 2004

Doctors must choose and manage implanted cardiac defibrillators patients carefully

Implanted devices that can shock a failing heart back into regular rhythm do an excellent job of keeping patients alive, two new University of Michigan studies find.

8 Nov 2004

Prevalence of occult HBV in hemodialysis patients is 4 to 5 times higher than standard HBsAg testing would suggest

Some kidney dialysis patients contract hepatitis B virus (HBV) during the course of their treatment, possibly from other members of the dialysis population with occult HBV.

8 Nov 2004

Obesity could more than double an older woman's risk of acute myelogenous leukemia

A study from the University of Minnesota Cancer Center indicates that overweight and obesity could more than double an older woman's risk of acute myelogenous leukemia (AML), an often fatal cancer of the bone marrow and blood.

8 Nov 2004

The first test in humans of a bioartificial kidney

The first test in humans of a bioartificial kidney offers hope of the device's potential to save the lives of people with acute renal failure, researchers at the University of Michigan Health System report.

4 Nov 2004

Smart stethoscope for monitoring the effectiveness of treatments to shatter kidney stones

Professor Tim Leighton from the University of Southampton's world-renowned Institute of Sound and Vibration Research (ISVR) and Dr Andrew Coleman, of Guy's and St Thomas NHS Foundation Trust are developing with industry a 'smart stethoscope' for monitoring the effectiveness of treatments to shatter kidney stones.

2 Nov 2004

Possible treatment for the fatal lung disease idiopathic pulmonary fibrosis

They found that the anti-cancer drug imatinib mesylate — commercially known as Gleevec and produced by Novartis Pharmaceuticals — can target a gene critical to controlling the disease process. Previously, there had been no treatment and patients usually did not survive beyond three years of diagnosis. Now the treatment is undergoing clinical trials at Mayo Clinic.

2 Nov 2004

Nephrology News and Research

Further Reading

A gallery of highly-specific, gene and protein “mug shots” of cancer types would be a powerful for oncologists

African Americans more likely to carry genetic variants known to stimulate inflammatory response

Key molecule helps identify renal cell carcinoma

Type 1 diabetes could be prevented by a new nasal insulin vaccine

Scientists have induced human insulin-producing cells of the pancreas to revert to islet precursor cells

Bypass surgery on a beating heart is an excellent option for many patients with blocked heart arteries

Researchers have found that a blood-reduction program in cardiac surgery results in a reduced need for transfusions

Carbon coatings to prevent bacteria collecting on indwelling catheters

Generic antipsychotic drugs can protect brain cells from progressive multifocal leukoencephalopathy

Sit down rounds improve outcomes for kidney dialysis patients

Researchers find effective treatment for Unusual Fever Syndrome caused by cold exposure

Fluorescent protein tool may speed identification of molecular changes that reveal cells' inner workings

Too much vitamin supplementation could be harmful

Lorus Therapeutics allowed Canadian patent to protect anticancer drugs

Doctors must choose and manage implanted cardiac defibrillators patients carefully

Prevalence of occult HBV in hemodialysis patients is 4 to 5 times higher than standard HBsAg testing would suggest

Obesity could more than double an older woman's risk of acute myelogenous leukemia

The first test in humans of a bioartificial kidney

Smart stethoscope for monitoring the effectiveness of treatments to shatter kidney stones

Possible treatment for the fatal lung disease idiopathic pulmonary fibrosis

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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