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Organoids in cell culture dish offer new insights into development of the brain

A new method could push research into developmental brain disorders an important step forward. This is shown by a recent study at the University of Bonn in which the researchers investigated the development of a rare congenital brain defect.

4 Apr 2017

Pioneering IVF technique offers hope to families with inheritable mitochondrial disorders

Details of a pioneering IVF technique using mitochondrial replacement therapy (MRT) have been revealed, giving hope to those families with inheritable mitochondrial disorders that they may be able to have healthy children in the future.

3 Apr 2017

Experts report serious limitations to technology for screening embryos

The healthy development of an embryo created through in vitro fertilization (IVF) depends on whether most, if not all, of the cells have the proper number of chromosomes.

31 Mar 2017

Researchers visualize development of blood vessels in zebrafish embryos

For the first time, researchers have followed the development of blood vessels in zebrafish embryos without using any labels or contrast agents, which may disturb the biological processes under study.

30 Mar 2017

Fluctuation in intracellular calcium ion concentration impacts brain shape

The first step in shaping the brain is that the neural plate, a sheet-like cell layer, curves to form the neural tube. Assistant Professor Makoto Suzuki of the National Institute for Basic Biology, Professor Naoto Ueno, and their colleagues have shown that during the process of neural tube formation a transient increase in the concentration of calcium ions in cells causes these morphological changes and is essential for neural tube formation.

30 Mar 2017

Researchers shed light on genome reorganization after fertilization in single-cell mammalian embryo

Using a newly developed method researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences have been able to shed light on the complexity of genome reorganization occurring during the first hours after fertilization in the single-cell mammalian embryo

30 Mar 2017

Researchers identify new gene mutation that leads to infertility in women

It has been estimated that more than 80 million people in the world have an unfulfilled desire to have children. But for every 10th couple, the reasons therefor remain unclear.

28 Mar 2017

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Researchers at Baylor College of Medicine, Texas Children's Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals.

22 Mar 2017

World's first licence for mitochondrial donation IVF may enable women to have disease-free babies

Eminent UK reproductive and genetics experts have become the first in the world licensed to provide a revolutionary IVF procedure using donor DNA – which they spent decades developing – enabling women carrying potentially fatal mitochondrial disease to have healthy, genetically-related babies.

20 Mar 2017

Research on repair of broken hearts hints at possibility of new designer cardiovascular therapies

Unlike the self-repair abilities of our skin, bone and other tissues, which can readily heal and rebuild themselves after injury, evolution has left the mammalian heart with relatively little regenerative capacity.

22 Feb 2017

OIST researchers employ time-lapse imaging technique to observe lens development in zebrafish

There are many different structures in our eyes that work in conjunction to allow us to see. These structures are strikingly similar between different species, from zebrafish to humans.

15 Feb 2017

Research: Daylight savings time contributes to higher miscarriage rates among IVF patients

Daylight savings time contributes to higher miscarriage rates among women undergoing in vitro fertilization who had had a prior pregnancy loss according to new research out of Boston Medical Center and IVF New England.

8 Feb 2017

Studies open new windows into understanding untreatable group of common genetic disorders

Two Princeton University studies are opening important new windows into understanding an untreatable group of common genetic disorders known as RASopathies that are characterized by distinct facial features, developmental delays, cognitive impairment and heart problems.

7 Feb 2017

Novel evidence-based tool provides guidance for women on elective egg freezing

The American Society for Reproductive Medicine lifted the experimental status for egg freezing in October 2012, and since then the popularity of elective egg freezing has been on the rise.

7 Feb 2017

Uterine glands produce several key factors for embryo growth and pregnancies, study shows

The majority of pregnancy losses occur during the first trimester, when biological communication between the embryo and mother is critical for the establishment of the pregnancy.

7 Feb 2017

Transporters of thyroid hormones play key role in development of the brain, study finds

Thyroid hormones are very important for the development of the brain. And when the transporters of these hormones are not functioning properly, the consequences for the development of the cerebellum or 'the little brain' are very serious.

6 Feb 2017

ACMG issues new Points to Consider statement on potential clinical application of genome editing

The American College of Medical Genetics and Genomics is weighing in on the genome editing/CRISPR debate with a new Points to Consider statement, "Genome Editing in Clinical Genetics."

29 Jan 2017

Human cells integrated into pig and cow embryos

Scientists have shown for the first time that undifferentiated human stem cells can be integrated into early embryos of both pigs and cattle. The construction of such interspecies embryos may represent an important development in the generation of organs for transplant.

27 Jan 2017

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

Mouse pancreases grown in rats generate functional, insulin-producing cells that can reverse diabetes when transplanted into mice with the disease, according to researchers at the Stanford University School of Medicine and the Institute of Medical Science at the University of Tokyo.

25 Jan 2017

UI biologists discover protein that appears to regulate chromosome movement

Before an egg becomes fertilized, sets of chromosomes must pair up to pass along genetic information. This happens within each reproductive cell, where separate chromosomes of male and female origin move toward each other and eventually join.

25 Jan 2017

Embryo News and Research

Organoids in cell culture dish offer new insights into development of the brain

Pioneering IVF technique offers hope to families with inheritable mitochondrial disorders

Experts report serious limitations to technology for screening embryos

Researchers visualize development of blood vessels in zebrafish embryos

Fluctuation in intracellular calcium ion concentration impacts brain shape

Researchers shed light on genome reorganization after fertilization in single-cell mammalian embryo

Researchers identify new gene mutation that leads to infertility in women

Researchers uncover gene mutation that may provide answers to unexplained female infertility

World's first licence for mitochondrial donation IVF may enable women to have disease-free babies

Research on repair of broken hearts hints at possibility of new designer cardiovascular therapies

OIST researchers employ time-lapse imaging technique to observe lens development in zebrafish

Research: Daylight savings time contributes to higher miscarriage rates among IVF patients

Studies open new windows into understanding untreatable group of common genetic disorders

Novel evidence-based tool provides guidance for women on elective egg freezing

Uterine glands produce several key factors for embryo growth and pregnancies, study shows

Transporters of thyroid hormones play key role in development of the brain, study finds

ACMG issues new Points to Consider statement on potential clinical application of genome editing

Human cells integrated into pig and cow embryos

Islets from rat-grown mouse pancreases can help reverse disease in diabetic mice

UI biologists discover protein that appears to regulate chromosome movement

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