Glucose Metabolism News and Research

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Piolitazone shows promise for preventing brain injury from radiation therapy

Researchers at Wake Forest University School of Medicine are the first to report that in animal studies, a common diabetes drug prevents the memory and learning problems that cancer patients often experience after whole-brain radiation treatments.

10 Jan 2007

Lots of sweet food and drink increases risk of pancreatic cancer

Pancreatic cancer is a very serious form of cancer that is possibly caused when the pancreas produces heightened levels of insulin as a consequence of upset glucose metabolism. A well-known way of increasing insulin production is to eat a lot of sugar.

8 Nov 2006

MRI tracks survival of pancreatic islets after transplantation

Magnetic resonance imaging (MRI) with an approved contrast agent may provide a practical way of monitoring the survival of transplanted pancreatic islets.

12 Sep 2006

Disabling carbohydrate trigger reduces obesity and appetite

Until about 15 years ago, insulin was believed primarily responsible for turning carbohydrates into fat. But then it became apparent that diet alone could stimulate glucose metabolism and fat synthesis, even when insulin levels were low or absent.

30 Aug 2006

Protein represents new target in the treatment of diabetes

According to a new study elevated levels of a molecule called RBP4 (retinol binding protein 4) forecast the early stages of the development of insulin resistance, a major cause of type 2 diabetes as well as cardiovascular disease and metabolic syndrome.

18 Jun 2006

Dietary glycemic index and carbohydrate in relation to early age-related macular degeneration

Age-related macular degeneration (AMD) is one of the leading causes of vision loss in older adults and a person's risk may partly depend upon diet.

6 Jun 2006

New study may advance treatments to prevent type 2 diabetes and metabolic syndrome

Insulin uses two distinct mechanisms to control glucose and the metabolism of blood fats (lipids) in the liver, a new Joslin Diabetes Center-led study has discovered.

23 May 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

Brain scan could reveal who will get Alzheimer's disease

According to researchers in California, a brain scan may possibly identify structural and metabolic brain changes that predict dementia or cognitive decline in normal older adults.

3 May 2006

High glucose-uptake tumors can be identified with PET scans

Cervical cancers that take up a lot of blood sugar, or glucose, are more resistant to treatment than those that are less glucose-hungry, according to research at Washington University School of Medicine in St. Louis.

4 Apr 2006

Genes play a key role in stress response

Both nature and nurture - genetic makeup and the environment experienced through life - combine to influence health and well-being, Duke University Medical Center researchers and their colleagues have determined in four new studies.

7 Mar 2006

Brain scans may detect neurological decline in normal people

Brain scans may detect neurological changes in people who exhibit no outward signs of cognitive decline but who later develop dementia or mental impairment, according to the results of a new study led by researchers at the University of California, Berkeley.

16 Feb 2006

Chromium helps muscles become more efficient

Researchers found that daily use of chromium picolinate enhanced muscle sensitivity to insulin in obese, insulin-resistant rats

7 Feb 2006

Microfluidics chips for simplifying medical imaging biomarkers of disease

A collaboration between scientists at UCLA, Caltech, Stanford, Siemens and Fluidigm have developed a new technology using integrated microfluidics chips for simplifying, lowering the cost and diversifying the types of molecules used to image the biology of disease with the medical imaging technology, Positron Emission Tomography (PET).

15 Dec 2005

How protein-enriched meals decrease hunger and reduce eating

Researchers have uncovered new evidence to explain the observation that diets rich in protein stunt the appetite, according to a report in the November Cell Metabolism.

13 Nov 2005

Combining fMRI and PET scanning creates a way to compare different measurements of the brain's function concurrently

Clinical researchers from the University of Pennsylvania Health System (UPHS) are the first to combine fMRI and PET scanning in radiology, creating a way to compare different measurements of the brain's function concurrently. This analysis could lead to better diagnosis and treatment in patients suffering from brain disorders, like Alzheimer's disease.

12 Oct 2005

PET imaging with FDG represents one of the most promising tools for diagnosis of Alzheimer's

Positron emission tomography (PET) imaging--with the radiotracer fluorodeoxyglucose (FDG)--is a promising tool in detecting Alzheimer's disease in patients who have mild cognitive impairment (MCI), according to a study reported in the October issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

5 Oct 2005

Increasing sugar processing in the liver may lead to future treatments for diabetes, obesity

Researchers at the University of Minnesota have shown that increasing the concentration of a key regulator involved in glucose metabolism can improve the way the liver produces and disposes of the sugar glucose, the primary fuel of the body. Finding ways to increase that concentration could provide a treatment for diabetes and obesity.

22 Aug 2005

Losing weight cuts breast cancer risk

An international team of scientists has found that young women who carry a breast cancer gene, can reduce their risk of the disease by up to 65% by attaining a healthy bodyweight.

21 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005