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Amgen to discuss data supporting Repatha BLA for high cholesterol treatment with FDA EMDAC

Amgen today announced that the Company will discuss the data supporting the Repatha (evolocumab) Biologics License Application (BLA) for the treatment of high cholesterol with the U.S. Food and Drug Administration's (FDA) Endocrinologic and Metabolic Drugs Advisory Committee (EMDAC).

10 Jun 2015

Study highlights the need to reduce non-communicable diseases

There is a great need to slow down the increasing number of people who die prematurely because of non-communicable diseases (NCDs) such as cardiovascular disease, diabetes and cancer.

10 Jun 2015

UC Davis researchers show feasibility of using statins to treat asthma

Statins continue to show that their benefits extend beyond their original focus of lowering high cholesterol. With the increasing prevalence of asthma, scientists are studying the effects of statins in the lungs.

26 May 2015

Researchers use American College of Cardiology registry to improve cardiovascular care delivery in India

Despite challenges, it is feasible to collect and study the quality of outpatient cardiovascular care in a resource-limited environment like India, according to a pilot study published today in the Journal of the American Heart Association.

20 May 2015

Study explores non-biological factors that may cause fewer men to seek bariatric surgery

A new study by researchers at the University of California, San Diego School of Medicine has identified demographic, socioeconomic and cultural factors that contribute to a major gender disparity among U.S. men and women undergoing weight loss surgeries. Men undergo the surgeries in far lower numbers than women.

30 Apr 2015

Chemists working to develop 'greener' processes for discovering, developing medicines

Chemists funded by NIH's National Institute of General Medical Sciences are working to develop "greener" processes for discovering, developing and manufacturing medicines and other molecules with therapeutic potential, as well as compounds used in biomedical research.

22 Apr 2015

UC San Diego study examines counterfeit drug penetration in global medicine supply chains

When you take a medication for, say, high cholesterol, do you know that pill is really what the label says it is? Depending upon the type of medicine and where you live, the threat of falsified medications (also referred to as counterfeit, fraudulent, and substandard) can be quite real, yet the full scope and prevalence of the problem is poorly understood, say researchers at University of California, San Diego School of Medicine in a new report published April 20 in the American Journal of Tropical Medicine and Hygiene.

21 Apr 2015

Majority of patients who survive cardiac arrest experience cognitive problems

Half of all patients who survive a cardiac arrest experience problems with cognitive functions such as memory and attention.

17 Apr 2015

Genetic study may help identify novel targets for treatment of high blood pressure

A genetic investigation of individuals in the Framingham Heart Study may prove useful to identify novel targets for the prevention or treatment of high blood pressure. The study, which takes a close look at networks of blood pressure-related genes, is published in the journal Molecular Systems Biology.

17 Apr 2015

Aspirin use continues to surge among older adults in US

A national survey suggests that slightly more than half of the older adults in the United States are now taking a daily dose of aspirin, even though its use is not recommended by the Food and Drug Administration for most people who have not yet had a heart attack or stroke.

17 Apr 2015

Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

Eisai Inc. and Arena Pharmaceuticals, Inc. today announced the completion of two Phase 1 registrational clinical trials that Eisai and Arena believe demonstrate bioequivalence of an investigational once-daily extended release formulation of lorcaserin, as compared to the twice-daily immediate release formulation approved by the US Food and Drug Administration and marketed as BELVIQ.

13 Apr 2015

Egg consumption may lower type 2 diabetes risk

Egg consumption may reduce the risk of type 2 diabetes, according to new research from the University of Eastern Finland. The findings were published in American Journal of Clinical Nutrition.

2 Apr 2015

EnteroMedics, American HealthCare Lending partner to support patient access to vBloc Therapy

EnteroMedics Inc., the developer of medical devices using neuroblocking technology to treat obesity, metabolic diseases and other gastrointestinal disorders, today announced that the Company has entered into a partnership with American HealthCare Lending to provide funding for patient access to vBloc Therapy, delivered via the Maestro Rechargeable System, for the treatment of obesity.

1 Apr 2015

FGF21 protein can boost regenerative effects of human PPARα

Researchers at UC Davis have illuminated an important distinction between mice and humans: how human livers heal. The difference centers on a protein called PPARα, which activates liver regeneration. Normally, mouse PPARα is far more active and efficient than the human form, allowing mice to quickly regenerate damaged livers.

1 Apr 2015

New study finds that walnuts have potential to benefit overall health

Multiple new research abstracts suggest walnuts may have the potential to positively affect several important health factors. From their impact on colon cancer and certain aspects of cognitive aging, to their positive effect on both gut health and vascular health, the research findings presented at Experimental Biology 2015 detail our latest understanding of walnuts' inner workings.

31 Mar 2015

Useful tips for physicians to help patients make the right choice on statin drugs

Cholesterol-lowering statins have transformed the treatment of heart disease. But while the decision to use the drugs in patients with a history of heart attacks and strokes is mostly clear-cut, that choice can be a far trickier proposition for the tens of millions of Americans with high cholesterol but no overt disease.

31 Mar 2015

Griffith research examines GPs’ confidence in providing nutritional advice to patients

The role of nutrition as part of a healthy lifestyle is well understood by the medical profession but whether this information is easily conveyed to patients is another matter. How much confidence GPs have in providing nutritional advice to their patients is now the subject of research by Griffith University’s Dr Lauren Ball.

27 Mar 2015

Research suggests genetic predisposition to spontaneous coronary artery disease

A Mayo Clinic study has identified a familial association in spontaneous coronary artery dissection, a type of heart attack that most commonly affects younger women, suggesting a genetic predisposition to the condition, researchers say.

24 Mar 2015

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Amgen today announced that an application seeking marketing approval of Repatha (evolocumab) for the treatment of high cholesterol has been submitted for review to the Ministry of Health, Labour and Welfare in Japan.

21 Mar 2015

Health care system-level factors may increase likelihood of medication adherence among seniors

Specific system-level factors controlled by health care systems - including prescriptions with a medication supply greater than 90 days, mail-order pharmacy use, and lower copayments and out-of-pocket maximums - nearly doubled the likelihood that patients adhered to prescribed heart and diabetes medications, according to a new study published in the journal Medical Care.

18 Mar 2015

High Cholesterol News and Research

Amgen to discuss data supporting Repatha BLA for high cholesterol treatment with FDA EMDAC

Study highlights the need to reduce non-communicable diseases

UC Davis researchers show feasibility of using statins to treat asthma

Researchers use American College of Cardiology registry to improve cardiovascular care delivery in India

Study explores non-biological factors that may cause fewer men to seek bariatric surgery

Chemists working to develop 'greener' processes for discovering, developing medicines

UC San Diego study examines counterfeit drug penetration in global medicine supply chains

Majority of patients who survive cardiac arrest experience cognitive problems

Genetic study may help identify novel targets for treatment of high blood pressure

Aspirin use continues to surge among older adults in US

Eisai, Arena complete two Phase 1 registrational trials for once-daily formulation of lorcaserin

Egg consumption may lower type 2 diabetes risk

EnteroMedics, American HealthCare Lending partner to support patient access to vBloc Therapy

FGF21 protein can boost regenerative effects of human PPARα

New study finds that walnuts have potential to benefit overall health

Useful tips for physicians to help patients make the right choice on statin drugs

Griffith research examines GPs’ confidence in providing nutritional advice to patients

Research suggests genetic predisposition to spontaneous coronary artery disease

Amgen seeks marketing approval of Repatha (evolocumab) in Japan for treatment of high cholesterol

Health care system-level factors may increase likelihood of medication adherence among seniors

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