Immune Response News and Research

RSS

Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis, which is the process of breaking blood clots, and heightened inflammatory responses.

3 Oct 2024

New study could lead to a more potent treatment option for multiple sclerosis

Multiple Sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer around nerve cells, known as the myelin sheath.

2 Oct 2024

Nanocapsules for glucagon offer a new approach to prevent hypoglycemia

People with diabetes take insulin to lower high blood sugar. However, if glucose levels plunge too low - from taking too much insulin or not eating enough sugar - people can experience hypoglycemia, which can lead to dizziness, cognitive impairment, seizures or comas.

2 Oct 2024

Long-lived plasma cells fail to establish after COVID mRNA vaccination, limiting long-term antibody response

Researchers found that SARS-CoV-2-specific plasma cells were largely excluded from the long-lived plasma cell compartment in the bone marrow after mRNA vaccination, explaining the short-lived antibody response.

2 Oct 2024

New humanized mouse models created to study COVID-19

Scientists at La Jolla Institute for Immunology (LJI) have developed six lines of humanized mice that can serve as valuable models for studying human cases of COVID-19.

1 Oct 2024

Inflammatory proteins linked to higher risk of endometrial cancer

Study identifies key inflammatory and immune response proteins linked to endometrial cancer risk through both observational and Mendelian Randomization analyses, revealing the roles of IL-6 and HSD11B1.

1 Oct 2024

New mechanism uncovered behind immune decline after tuberculosis treatment

Researchers at Baylor College of Medicine and collaborating institutions have discovered a mechanism that drives the long-term decline in immune response that is observed after tuberculosis (TB) has been successfully treated.

1 Oct 2024

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

Immune modulation as a new strategy to combat periodontal disease

Targeting the immune system could prevent or treat periodontal disease (PD), a common but serious disease of the gums, according to new research from the University of Pittsburgh.

30 Sep 2024

Macrophage memory following COVID infection provides cross-virus protection

More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime.

30 Sep 2024

Study shows gradual waning of MMR vaccine effectiveness over time

The MMR vaccine remains the best protection against measles, according to a modelling study in England which suggests the level of protection decreases slightly over time.

27 Sep 2024

Study: MMR vaccine remains the most effective measure to prevent measles infection

Most measles cases in England are among unvaccinated individuals. But, between 2011 and 2019, the proportion of measles cases in adults who received two doses of the MMR vaccine in England increased from 1.9% (20/1064) to 7.2% (57/790), however the cause of this increase remains unclear.

26 Sep 2024

Perceived stress can directly trigger psoriasis relapse

Innovative research has provided compelling evidence that perceived stress can directly trigger the relapse of psoriatic skin lesions. The study, presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2024, is the first to scientifically validate this connection in vivo.

26 Sep 2024

Study reveals positive correlation between type 2 immunity and long-term cancer remission

Results from a preclinical study in mice, led by EPFL, and a collaborative clinical study in patients show that the type 2 immune response – associated with parasitic infection and thought to play a negative role in cancer immunity – is positively correlated with long-term cancer remission.

26 Sep 2024

Targeting tumor immunity with transferrin receptor-directed photodynamic therapy

This new article publication from Acta Pharmaceutica Sinica B, discusses a transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB interruption.

26 Sep 2024

New biomarker profiling enhances early detection of melanoma

Innovative research has unveiled promising advancements in melanoma detection, which could significantly enhance diagnosis and prognosis by identifying the disease at its earliest, most treatable stages.

25 Sep 2024

Study reveals how inflammatory immune cells enhance prostate cancer resistance

There is a challenge related to prostate and many other cancers that cancer cells form resistance to treatments as the disease progresses. However, these resistance mechanisms are not yet fully understood.

24 Sep 2024

Key triggers for food allergies in children after organ transplants

Study reviews transplant-acquired food allergies, focusing on pediatric patients, particularly liver transplant recipients. It explores immune system dysfunction, immunosuppressive agents, and gut microbiota changes as contributors to the rise of food allergies after organ transplants.

23 Sep 2024

Dietary antigens reduce small intestine cancer by boosting immune T-cells

Study shows that dietary antigens can suppress small intestine carcinogenesis by activating T-cells through Peyer's patches. Adding bovine serum albumin (BSA) or ovalbumin (OVA) to antigen-free diets restored immune function and reduced tumor growth in mice.

22 Sep 2024

Fever enhances immune cell activity and induces mitochondrial stress

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also - in a particular subset of T cells - cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered.

20 Sep 2024