Malignant News and Research

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Study: Diet can influence the breast microbiome and alter breast cancer tumors

When people think of microbiome, they typically think about the gut, but there's also a breast microbiome, and the role it plays in breast health and breast cancer isn't thoroughly understood. A microbiome is the collection of microorganisms that live in a particular environment in the body.

4 Jun 2021

New nano-sized particles help improve detection of tumors within the body

Nano-sized particles have been engineered in a new way to improve detection of tumors within the body and in biopsy tissue, a research team in Sweden reports. The advance could enable identifying early stage tumors with lower doses of radiation.

3 Jun 2021

Optic nerve activity may trigger the formation of vision-harming tumors in children

In a study of mice, researchers showed how the act of seeing light may trigger the formation of vision-harming tumors in young children who are born with neurofibromatosis type 1 (NF1) cancer predisposition syndrome.

2 Jun 2021

The LUCA device shows high accuracy in thyroid cancer screening

Thyroid nodules are a common pathology having a prevalence of 19-76% when screened with ultrasound, with higher frequencies in women.

1 Jun 2021

Study shows that breast cancer can be prevented with better contraception choices

Hormonal contraceptives, e.g. the pill, the patch, and the vaginal ring, contain synthetic hormones that prevent pregnancy by either stopping ovulation, changing the cervical mucus to stop sperm from passing through the cervix and finding an egg, or changing the womb's lining to prevent a fertilized egg from being implanted in it.

29 May 2021

Study examines impact of chemotherapy on mechanical properties of prostate cancer cells

Malignant tumor cells undergo mechanical deformation more easily than normal cells, allowing them to migrate throughout the body.

28 May 2021

Targeting mTOR pathway can improve the effectiveness of chemotherapies for pediatric brain cancer

Two experimental drug approaches that target vulnerabilities in cancer cell metabolism may extend survival and enhance the effectiveness of standard chemotherapies for a highly aggressive type of pediatric brain cancer.

21 May 2021

Study describes differences between mutation profile of acral nevi and acral melanoma

Melanocytic nevi, or moles, are nonmalignant growths that arise from pigment producing cells of the skin.

12 May 2021

Personalized vaccine can provide effective immunization against cancer

Marie-Claude Bourgeois-Daigneault and her team at the CRCHUM are using mice to show how a combination of peptides and oncolytic viruses, used as an adjuvant, can provide effective immunization against cancer.

11 May 2021

Using ultrasound and RNA-loaded nanoparticles to deliver potent medicine to brain tumors

RNA-based drugs have the potential to change the standard of care for many diseases, making personalized medicine a reality. This rapidly expanding class of therapeutics are cost-effective, fairly easy to manufacture, and able to go where no drug has gone before, reaching previously undruggable pathways.

7 May 2021

New strategy could increase the effectiveness of chemotherapy treatments

New research led by a team at Massachusetts General Hospital (MGH) points to a promising strategy to boost tumors' intake of cancer drugs, thereby increasing the effectiveness of chemotherapy treatments.

7 May 2021

UMass Amherst researchers achieve breakthrough in the fight against cancer

A team of researchers at the Center for Bioactive Delivery at the University of Massachusetts Amherst's Institute for Applied Life Sciences has engineered a nanoparticle that has the potential to revolutionize disease treatment, including for cancer.

6 May 2021

Key mechanism behind mutant p53 aggregation process is linked to cancer pathology

Cancer has been recently shown to be affected by protein clusters, particularly by the aggregation of mutant variants of the tumor suppressor protein p53, which are present in more than half of malignant tumors.

5 May 2021

Certain immune cells can cause damage to the aging nervous system, study finds

Aging is the biggest risk factor for perturbation of the nervous system, even in the absence of distinct disease or trauma.

4 May 2021

Study reveals major factors that affect bone health in hematopoietic stem cell transplantation recipients

Impaired bone health is among the most significant long-term consequences of hematopoietic stem cell transplantation (HSCT), a common therapy for patients with malignant and non-malignant hematological diseases.

4 May 2021

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

A protein variant common in malignant bladder tumor cells may serve as a new avenue for treating bladder cancer.

29 Apr 2021

Mutation in a cancer-causing gene could exacerbate cerebral cavernous malformations in the brain

Researchers have discovered an explanation for why cerebral cavernous malformations (CCMs)--clusters of dilated blood vessels in the brain--can suddenly grow to cause seizures or stroke.

28 Apr 2021

Cholestenone could be a new antibacterial drug against H. pylori

Helicobacter pylori (H. pylori), a gram-negative pathogen that has infected half of the world's population is a Group I carcinogen according to the WHO. H. pylori resides in the gastric mucosa causing gastritis, ulcers, gastric cancers and malignant lymphoma of the stomach.

27 Apr 2021

Prolactin hormone acts as a major contributor to breast cancer development, studies find

The hormone prolactin has long been understood to play a vital role in breast growth and development and the production of milk during pregnancy.