Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Lung protein hyperconcentration may be a key factor in predicting COPD risks

Airway mucus consists of various proteins such as long mucins MUC5AC and MUC5B, both of which contribute greatly to the proper gel-like consistency of this most essential bodily fluid.

3 Jun 2021

Study: Lung squamous patients harboring druggable mutations have lower median overall survival

Oncotarget published "Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations" which reported that unlike lung adenocarcinoma patients, there is no FDA-approved targeted-therapy likely to benefit lung squamous cell carcinoma patients.

3 Jun 2021

Sinai Health researchers provide an ultra-detailed look at the organization of human cells

Researchers from Sinai Health have published a study providing an ultra-detailed look at the organization of a living human cell, providing a new tool that can help scientists around the world better understand what happens during disease.

2 Jun 2021

Rapid Novor First to Decode Polyclonal Antibodies Using Only Proteomics

Novel antibody discovery platform REpAb® unlocks direct access to key antibodies through next-generation protein sequencing

From Rapid Novor Inc 27 May 2021

Waters Introduces the SARS-CoV-2 LC-MS Kit (RUO) to Advance Clinical Research of Infectious Diseases

Waters Corporation today introduced a new RUO LC-MS test method to advance critical infectious disease research.

From Waters Corporation 27 May 2021

Proteomics technology shows how exercise improves the efficiency of muscle energy production

Mitochondria are the cell's power plants and produce the majority of a cell's energy needs through an electrochemical process called electron transport chain coupled to another process known as oxidative phosphorylation.

27 May 2021

Biognosys Announces the Appointment of Kristina Beeler as Chief Business Officer

Biognosys announces the appointment of Kristina Beeler as Chief Business Operator

From Biognosys 21 May 2021

New method provides greater quality control and safety of heparin drug

A new method to analyze the blood thinning drug Heparin has been developed that can pinpoint contaminants more accurately and quickly, providing greater quality control and safety.

17 May 2021

SARS-CoV-2 Nsp2 structure revealed by cryo-EM and AI

Researchers in the United States analyzed the non-structural protein 2 (Nsp2) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in order to better understand its function and to guide future drug discovery. The research paper is currently available on bioRxiv* preprint server.

16 May 2021

Phosphatidic acid is a key common substrate for hepatitis C and SARS-CoV-2 replication

A new study, released as a preprint on the bioRxiv* server, focuses on the lipid molecule called phosphatidic acid (PA), showing its crucial role in the replication of this virus, and thus its potential as a target for therapeutic intervention.

13 May 2021

Oleoyl-LPE promotes neurite outgrowth and protects against neuronal cell death

Lysophospholipids are phospholipids that have just one fatty acid chain, and in recent years, the role of lysophospholipids in physiology and pathophysiology has attracted attention.

12 May 2021

Researchers design compounds that prevent SARS-CoV-2 entry in human lung cells

Researchers have designed a new class of TMPRSS2 inhibitors that have shown broad antiviral activity against coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 May 2021

Cryptic pocket on the surface of SARS-CoV-2 may be a promising treatment target

In a new study currently available on the bioRxiv* preprint server, a multinational group of researchers modeled an entire membrane-embedded spike glycoprotein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and highlighted the potential of a specific mapping approach for unveiling cryptic, potentially druggable pockets on the viral surface.

7 May 2021

New combination treatment could benefit T-ALL patients who do not respond to chemotherapy

T-cell acute lymphoblastic leukemia is an aggressive cancer type that mostly affects children. The standard treatment is chemotherapy, but about one in four patients do not respond or develop resistance to this.

4 May 2021

Monitoring O2 and CO2 Using Benchtop Bioreactors

Discover how to monitor O2 and CO2 Using Benchtop Bioreactors.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 30 Apr 2021

Two compounds can cause musty, moldy scents in cocoa

Chocolate is a beloved treat, but sometimes the cocoa beans that go into bars and other sweets have unpleasant flavors or scents, making the final products taste bad.

28 Apr 2021

CU Cancer Center researchers receive PRCRP grant to investigate metastasis

Two members of the University of Colorado Cancer Center have received prestigious Idea Awards from the U.S. Department of Defense's Peer Reviewed Cancer Research Program.

27 Apr 2021

University-industry partnership leads to a new rapid COVID-19 test

A partnership between UC Davis and Maurice J. Gallagher, Jr., chairman and CEO of Allegiant Travel Company, has led to a new rapid COVID-19 test.

27 Apr 2021

Metabolic testing of COVID-19 patients through skin imprints

There is, therefore, a great need to understand how the illness can be diagnosed using more convenient and inexpensive methods. A new study posted to the medRxiv preprint server reveals the potential role of skin imprints to test for biomarkers that indicate a diagnosis of COVID-19 in a non-invasive way.

22 Apr 2021

Can sniffer dogs be trained to detect SARS-CoV-2 infection?

A new study in PLOS ONE discusses the novel use of dogs to sniff out the virus in patient samples as a potential additional diagnostic route to ease the situation.

21 Apr 2021