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GlaxoSmithKline receives CHMP positive opinion for REVOLADE

Ligand Pharmaceuticals Incorporated partner GlaxoSmithKline announced that today, the European Medicines Agency's Committee for Medicinal Products for Human Use issued a positive opinion recommending marketing authorization for GSK's REVOLADE (eltrombopag) as a treatment for low platelet counts (thrombocytopenia) in adult patients with chronic hepatitis C infection, where the degree of thrombocytopenia is the main factor preventing the initiation or limiting the ability to maintain optimal interferon-based therapy

26 Jul 2013

Novo Solutions MD announces releases of NovoScarMD scar cream

Novo Solutions MD announces the launch of NovoScarMD the most scientifically advanced scar cream to come to market in 10 years. NovoScarMD reverses existing and new scar damage, keloids, and stretch marks, and rapidly returns skin to its original state with almost no trace of skin injury

25 Jul 2013

Platelet activation inhibits host cell entry of HIV, shows research

Scientists of the DPZ have shown that platelet activation inhibits the host cell entry of HIV. Infection biologists of the German Primate Center (DPZ) under the direction of Stefan Pöhlmann have found evidence that platelets (thrombocytes) might constitute an innate defense against infection with the human immunodeficiency virus (HIV).

24 Jul 2013

AOSSM presents awards and grants to encourage research in orthopaedic sports medicine

In order to recognize and encourage cutting-edge research in key areas of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine (AOSSM) will present ten research awards and seven grants during its Annual Meeting, July 11-14 in Chicago, IL.

10 Jul 2013

Duke researchers solve some mysteries related to the use of aspirin

Aspirin has been widely used for more than 50 years as a common, inexpensive blood thinner for patients with heart disease and stroke, but doctors have little understanding of how it works and why some people benefit and others don't.

4 Jul 2013

Study shows activated blood platelets enable cancer cells to penetrate blood vessels

Malignant tumours often spread to remote areas of the body. In the majority of cases, metastases formation develops via the blood vascular system. The blood platelets thereby provide invaluable help to the tumour cells in penetrating new organs.

4 Jul 2013

CTI announces publication of preclinical, clinical data for pacritinib in Drugs of the Future 2013

Cell Therapeutics, Inc. today announced that a comprehensive article summarizing preclinical and clinical data for pacritinib, an oral JAK2/FLT3 inhibitor, authored by Srdan Verstovsek, M.D., Ph.D., et al., was published in the journal Drugs of the Future 2013.

3 Jul 2013

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

ARIAD Pharmaceuticals, Inc. today announced that the European Commission has granted a marketing authorization for Iclusig (ponatinib) as an orphan medicinal product for two indications.

2 Jul 2013

Ambit Biosciences presents data from Phase 2 ACE study of quizartinib for treatment of AML

Ambit Biosciences Corporation announced today data from the Phase 2 ACE study of quizartinib (AC220), a FLT3 inhibitor, were featured in multiple presentations at the 18th Congress of the European Hematology Association in Stockholm, Sweden.

27 Jun 2013

Study shows patients with avascular necrosis have turned to stem cell therapy for aid

Stem cells have long been touted as the next big thing. Well just maybe, it is here. According to Dr. Dennis Lox, some patients with a disorder of the bone called avascular necrosis (AVN), have turned to stem cell therapy for aid.

15 Jun 2013

Data demonstrate benefits of nurse-led programme on patient self-management of RA

Data first presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism demonstrate the benefits of a nurse-led programme on patient self-management and the management of rheumatoid arthritis co-morbidities.

14 Jun 2013

$Epidural steroid injection is associated with increased spinal fracture$

Epidural steroid injection is associated with increased spinal fracture

Most aging adults will experience back pain or a spinal disorder at some time in their life. In fact, about 25.8 million visits were made to physicians' offices due to primary back problems. Treatment focuses on pain relief and is available in both non-surgical (medication or physical therapy) and surgical forms.

7 Jun 2013

Does krill oil help your arthritis?

Arthritis is a condition that affects 1 in 5 Australians. That means that 1.4m people in NSW alone, have a form of arthritis and try to manage the impact it has on their lives. There are a number of very common and effective ways to tackle the condition such as physical activity and exercise, physical therapy, healthy eating and traditional medicines. All of these methods can play a role in reducing the pain arthritis causes in people’s daily lives.

5 Jun 2013

Study: New genetic marker predicts warfarin dose in African-Americans

A newfound genetic marker promises to better predict warfarin dose in African-Americans, according to a study published online today in The Lancet. If confirmed in further studies, the finding may help to avert more of the bleeds and blood clots that come when a patient's starting dose misses the drug's narrow safety window.

5 Jun 2013

Revised CPG on treatment of osteoarthritis of the knee addresses two key changes

The American Academy of Orthopaedic Surgeons recently released its revised clinical practice guideline on the treatment of osteoarthritis of the knee, addressing two key changes.

5 Jun 2013

TSRI scientists devise new technique to find therapeutic antibodies

Scientists at The Scripps Research Institute have devised a powerful new technique for finding antibodies that have a desired biological effect. Antibodies, which can bind to billions of distinct targets, are already used in many of the world's best-selling medicines, diagnostics and laboratory reagents.

24 May 2013

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs before it's dissolved, researchers reported in an early online publication at Nature.

24 May 2013

Neisseria meningitidis causes life threatening meningitis, meningococcal sepsis in humans

"Neisseria meningitidis is an important human pathogen that can cause rapidly progressing, life threatening meningitis and meningococcal sepsis in humans," Professor Jennings said.

24 May 2013

Antidepressant treatment results in lower rate of MSIMI

Among patients with stable coronary heart disease and mental stress-induced myocardial ischemia (MSIMI), 6 weeks of treatment with the antidepressant escitalopram, compared with placebo, resulted in a lower rate of MSIMI, according to a study in the May 22/29 issue of JAMA.

22 May 2013

Drug resistant brain tumors: an interview with Prof. Mischel, Ludwig Institute for Cancer Research and Prof. Bensinger, University of California

In cancer, mutations in proteins that control cell growth are common, leading to unrestrained cellular proliferation and tumor formation.

9 May 2013

Platelet News and Research

GlaxoSmithKline receives CHMP positive opinion for REVOLADE

Novo Solutions MD announces releases of NovoScarMD scar cream

Platelet activation inhibits host cell entry of HIV, shows research

AOSSM presents awards and grants to encourage research in orthopaedic sports medicine

Duke researchers solve some mysteries related to the use of aspirin

Study shows activated blood platelets enable cancer cells to penetrate blood vessels

CTI announces publication of preclinical, clinical data for pacritinib in Drugs of the Future 2013

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

Ambit Biosciences presents data from Phase 2 ACE study of quizartinib for treatment of AML

Study shows patients with avascular necrosis have turned to stem cell therapy for aid

Data demonstrate benefits of nurse-led programme on patient self-management of RA

Epidural steroid injection is associated with increased spinal fracture

Does krill oil help your arthritis?

Study: New genetic marker predicts warfarin dose in African-Americans

Revised CPG on treatment of osteoarthritis of the knee addresses two key changes

TSRI scientists devise new technique to find therapeutic antibodies

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Neisseria meningitidis causes life threatening meningitis, meningococcal sepsis in humans

Antidepressant treatment results in lower rate of MSIMI

Drug resistant brain tumors: an interview with Prof. Mischel, Ludwig Institute for Cancer Research and Prof. Bensinger, University of California

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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