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Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

A recent study presented topologically engineered fragment crystallizable-fusion proteins and antibodies as therapeutic options for diseases like human coronaviruses infections and cancers.

25 Mar 2022

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Researchers evaluated the neutralizing antibody titers and anti-receptor-binding domain immunoglobulin G titers in sera of kidney transplant recipients who were vaccinated against COVID-19 and treated with 300 mg dosage of Evusheld™

25 Mar 2022

Impact of truncated open reading frame 8 protein variants of SARS-CoV-2

A new study identified unique truncated open reading frame 8 proteins among SARS-CoV-2 sequences.

25 Mar 2022

Researchers characterize vaccines for infectious bronchitis virus

A new study characterized the genetic and immunological aspects of the infectious bronchitis virus (IBV) vaccines commercially used in Korea.

25 Mar 2022

Study investigates incident diabetes burden and risk in post-acute COVID-19 patients

Researchers examined the post-acute risk and burden of incident diabetes beyond the initial 30 days of COVID-19.

25 Mar 2022

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Researchers reported the efficacy of their self-developed CASCADE biosensor in naked-eye detection of SARS-CoV-2 RNA using gold nanoparticles.

25 Mar 2022

Study indicates combining a hydrogen peroxide-based disinfectant with cellulosic copper nanoparticles lowers human coronaviruses' infectivity

A recent study indicated that combining a hydrogen peroxide-based disinfectant and cellulosic copper nanoparticles lowered human coronaviruses' infectivity.

25 Mar 2022

Model for investigating the effect of mutations on the binding affinity of the SARS-CoV-2 RBD-ACE2 complex

Researchers used a CNN regression model to investigate the effect of mutations on the binding affinity of the SARS-CoV-2 RBD-ACE2 complex.

25 Mar 2022

Rutgers researchers use roundworms to unravel how cells communicate with one another

Scientists have long puzzled about a critical way that cells communicate with one another, but Rutgers researchers have used a simple roundworm to solve the mystery.

25 Mar 2022

Adaptive immunity against SARS-CoV-2 is persistent and robust in COVID-convalescent children

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection incites adaptive cellular immune responses. In many SARS-CoV-2 studies, peripheral blood is analyzed to study the immune responses. Now, a new study under consideration at the Nature Portfolio Journal analyzes the peripheral blood, tonsils, and adenoids of children to understand local and systemic immune responses to SARS-CoV-2.

25 Mar 2022

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

A team of international scientists has developed an mRNA-based coronavirus disease 2019 (COVID-19) vaccine encoding the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant. The vaccine candidate has shown high efficacy in inducing neutralizing antibodies and protecting against delta infection in mice. The study is currently available on the bioRxiv* preprint server.

24 Mar 2022

IgG Fc glycosylation: A marker for severe COVID-19

Researchers suggest that low anti-spike IgG1 glycosylation, sialyation, and high bisection are markers of severe COVID-19.

24 Mar 2022

Breast milk components show potent in vitro SARS-CoV-2 inhibition

Human breastmilk contains substances that can inhibit infection by SARS-CoV-2 and its variants, as well as prevent its replication.

24 Mar 2022

INRS professor developing a glycoconjugate vaccine for melioidosis

The threat from Melioidosis is real. The bacterium that causes this infectious multisymptom illness is resistant to antibiotics, making diagnosis and treatment more complex and resulting in a mortality rate of up to 50%.

24 Mar 2022

UB-612 vaccine booster found to elicit high neutralizing antibody levels against SARS-CoV-2 Omicron

Researchers evaluated the effectiveness of a novel vaccine candidate UB-612 against 14 SARS-CoV-2 variants, including the latest variant of concern, Omicron.

24 Mar 2022

Study evaluates humoral and cellular immune memory induced by different COVID-19 vaccines

Researchers evaluated the humoral and cellular immune memory induced by four COVID-19 vaccines representing three different vaccine platforms.

24 Mar 2022

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

A new study evaluated the N terminal domain of the SARS-CoV-2 nucleocapsid protein. It presented the targeted characteristics for selective ribonucleic acid identification by SARS-CoV-2 N in its 5'-genomic end.

24 Mar 2022

New SARS-CoV-2 Omicron-Delta recombinant virus identified in the US

Researchers reported a novel SARS-CoV-2 Omicron and Delta recombinant virus in the United States.

24 Mar 2022

Blood biomarker may uniquely aid prediction of dementia in Mexican Americans

Blood levels of a biomarker called glial fibrillary acidic protein (GFAP) may uniquely aid prediction of dementia in Mexican Americans, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and collaborating institutions reported March 24.

24 Mar 2022

Discovery could help explain why certain infections are hard to get rid of

A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections - such as urinary tract and bloodstream infections like sepsis- are hard to get rid of.

24 Mar 2022

Protein C News and Research

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Impact of truncated open reading frame 8 protein variants of SARS-CoV-2

Researchers characterize vaccines for infectious bronchitis virus

Study investigates incident diabetes burden and risk in post-acute COVID-19 patients

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Study indicates combining a hydrogen peroxide-based disinfectant with cellulosic copper nanoparticles lowers human coronaviruses' infectivity

Model for investigating the effect of mutations on the binding affinity of the SARS-CoV-2 RBD-ACE2 complex

Rutgers researchers use roundworms to unravel how cells communicate with one another

Adaptive immunity against SARS-CoV-2 is persistent and robust in COVID-convalescent children

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

IgG Fc glycosylation: A marker for severe COVID-19

Breast milk components show potent in vitro SARS-CoV-2 inhibition

INRS professor developing a glycoconjugate vaccine for melioidosis

UB-612 vaccine booster found to elicit high neutralizing antibody levels against SARS-CoV-2 Omicron

Study evaluates humoral and cellular immune memory induced by different COVID-19 vaccines

Study explores favorable signatures for specific RNA motif recognition by SARS-CoV-2 nucleocapsid

New SARS-CoV-2 Omicron-Delta recombinant virus identified in the US

Blood biomarker may uniquely aid prediction of dementia in Mexican Americans

Discovery could help explain why certain infections are hard to get rid of

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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