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Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

Joslin scientists have advanced understanding of how the cellular repair process is impaired in type 1 diabetes, which can cause cell death and lead to complications. The findings appear in the August issue of Cell Metabolism.

5 Aug 2015

CRI commits $29.3 million in new funds to accelerate development of cancer immunotherapies

The Cancer Research Institute, a nonprofit organization dedicated to fueling the discovery and development of immunotherapies for all forms of cancer, announced that it has committed more than $29.3 million in new funds to accelerate cancer immunology research and cancer immunotherapy clinical development in the United States, Australia, Canada, France, Sweden, Switzerland, and The Netherlands.

5 Aug 2015

Rice University scientists identify genetic mechanism that allows bacteria to resist antibiotics

Rice University scientists are developing strategies to keep germs from evolving resistance to antibiotics by heading them off at the pass.

5 Aug 2015

Access to dental care by low-income Americans becomes exception as only fewer dentists accept Medicaid

More than 2 percent of all emergency department visits are now related to nontraumatic dental conditions, according to a study by researchers at Stanford University, the University of California-San Francisco, Truven Health Analytics and the federal Agency for Healthcare Research and Quality.

5 Aug 2015

IP10 levels linked to HBsAg decline during TDF treatment

Baseline serum interferon-inducible protein 10 levels predict hepatitis B surface antigen reduction in patients with hepatitis B e antigen-negative chronic hepatitis B virus infection treated with tenofovir disoproxil fumarate, findings indicate.

4 Aug 2015

Armada, UMass Medical School partner to enhance ArmadaOne Specialty Pharmacy Workflow Platform

Armada Health Care has partnered with University of Massachusetts Medical School's Clinical Pharmacy Services business unit to provide enhancements and support regarding clinical protocols and therapy interventions within the ArmadaOne Specialty Pharmacy Workflow Platform.

4 Aug 2015

People with chronic insomnia may be able to get relief from half of standard sleeping pills

The roughly nine million Americans who rely on prescription sleeping pills to treat chronic insomnia may be able to get relief from as little as half of the drugs, and may even be helped by taking placebos in the treatment plan, according to new research published today in the journal Sleep Medicine by researchers from the Perelman School of Medicine at the University of Pennsylvania.

4 Aug 2015

Northwestern gets $17.5 million NIH grant to invent, develop implantable drug delivery system for HIV prevention

Northwestern Medicine scientists have received a five-year, $17.5 million grant from the National Institutes of Health for an interdisciplinary project that aims to invent, develop and test an implantable drug delivery system to protect high-risk individuals from HIV infection for up to a year at a time.

4 Aug 2015

Penn Medicine devises new approach to develop vaccines against lethal diseases

Researchers at the Perelman School of Medicine at the University of Pennsylvania have devised an entirely new approach to vaccines - creating immunity without vaccination.

4 Aug 2015

New big data collaboration aims to improve care management for diabetes, mental health

Duke-NUS Graduate Medical School Singapore and Holmusk, a global tele-health platform, have recently announced a collaboration to further the potential of big data in healthcare. Big data refers to very large, unstructured and diverse datasets that cannot be managed using conventional methods. In healthcare, big data and analytics allow us to discover patterns that would not be found otherwise, and make predictions about disease. This has the potential to improve care and lower costs.

4 Aug 2015

Common gout medications may offer protection from alcohol-induced liver disease, inflammation

New research in mice shows that two commonly used gout medications, which target uric acid and adenosine triphosphate, may offer protection from alcohol-induced liver disease and inflammation.

3 Aug 2015

U-M’s Taubman Health Sciences Library reopens as transformed space for learning, teaching

The books moved out two years ago, and the construction crews moved in. And today, the University of Michigan's Taubman Health Sciences Library reopens as a transformed space for learning, teaching and gathering.

3 Aug 2015

3D-printed models of children's brain anatomy help reduce operative risk of complex procedures

Boston Children's Hospital physicians report the first cases of children benefiting from 3D printing of their anatomy before undergoing high-risk brain procedures.

3 Aug 2015

BRCA gene mutations and ovarian cancer: an interview with Dr Matulonis, Harvard Medical School

The BRCA gene encodes for the BRCA proteins, BRCA1 and BRCA2. These proteins are very important in repairing DNA, which they do by correcting double-stranded breaks.

2 Aug 2015

Reducing incorrect gene expression can extend lifespan of cells

Working with yeast and worms, researchers found that incorrect gene expression is a hallmark of aged cells and that reducing such "noise" extends lifespan in these organisms. The team published their findings this month in Genes & Development.

31 Jul 2015

New synthetic gene drives could one day improve human health and the environment

Gene drives are genetic elements - found naturally in the genomes of most of the world's organisms - that increase the chance of the gene they carry being passed on to all offspring, and thus, they can quickly spread through populations. Looking to these natural systems, researchers around the world, including some Wyss Institute scientists, are developing synthetic gene drives that could one day be leveraged by humans to purposefully alter the traits of wild populations of organisms to prevent disease transmission and eradicate invasive species.

31 Jul 2015

Researchers reconstruct ancient virus to improve gene therapy

Researchers at Massachusetts Eye and Ear/Schepens Eye Research Institute have reconstructed an ancient virus that is highly effective at delivering gene therapies to the liver, muscle, and retina. This discovery, published July 30 in Cell Reports, could potentially be used to design gene therapies that are not only safer and more potent than therapies currently available, but may also help a greater number of patients.

31 Jul 2015

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

The importance of a diet rich in fish oils - now a billion dollar food-supplement industry -- has been debated for over half a century. A few large clinical trials have supported the idea that fish oils confer therapeutic benefits to patients with cardiovascular disease. Researchers think that hearts and blood vessels may benefit in part from their anti-inflammatory properties.

31 Jul 2015

Psychotropic medication use widespread among older adults, new study finds

Older Americans receive prescriptions for mental health medications at more than twice the rate that younger adults do, a new study finds.

31 Jul 2015

GW Cancer Institute receives Eugene Washington PCORI Engagement Award to create online site for patient-centered care

The George Washington University Cancer Institute has been approved for a $250,000 Eugene Washington PCORI Engagement Award by the Patient-centered Outcomes Research Institute to create the first-ever online Community of Practice for patient-centered care.

31 Jul 2015

Medical School News and Research

Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

CRI commits $29.3 million in new funds to accelerate development of cancer immunotherapies

Rice University scientists identify genetic mechanism that allows bacteria to resist antibiotics

Access to dental care by low-income Americans becomes exception as only fewer dentists accept Medicaid

IP10 levels linked to HBsAg decline during TDF treatment

Armada, UMass Medical School partner to enhance ArmadaOne Specialty Pharmacy Workflow Platform

People with chronic insomnia may be able to get relief from half of standard sleeping pills

Northwestern gets $17.5 million NIH grant to invent, develop implantable drug delivery system for HIV prevention

Penn Medicine devises new approach to develop vaccines against lethal diseases

New big data collaboration aims to improve care management for diabetes, mental health

Common gout medications may offer protection from alcohol-induced liver disease, inflammation

U-M’s Taubman Health Sciences Library reopens as transformed space for learning, teaching

3D-printed models of children's brain anatomy help reduce operative risk of complex procedures

BRCA gene mutations and ovarian cancer: an interview with Dr Matulonis, Harvard Medical School

Reducing incorrect gene expression can extend lifespan of cells

New synthetic gene drives could one day improve human health and the environment

Researchers reconstruct ancient virus to improve gene therapy

New Penn study questions relevance of fish oil-derived SPMs and their anti-inflammatory effects in humans

Psychotropic medication use widespread among older adults, new study finds

GW Cancer Institute receives Eugene Washington PCORI Engagement Award to create online site for patient-centered care

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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