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Understanding the mechanisms involved in heart disease and cancers

In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they've found the molecular mechanism by which the protein PCSK9 degrades the receptor of low density lipoproteins, the richest cholesterol particles in the bloodstream.

19 Jan 2023

How is long COVID diagnosed in adults?

In a recent study, researchers enlisted important points concerning post-coronavirus disease 2019 (COVID-19) or long COVID diagnosis among adults.

19 Jan 2023

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

Researchers explored the relationship between the development of goblet inflammatory cells and the age-related pathophysiology of SARS-CoV-2.

19 Jan 2023

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Researchers explored how mutations in emergent SARS-CoV-2 variants affect viral function, human immunity, and recognition by therapeutic antibodies.

19 Jan 2023

Berkeley Lights launches Beacon Select™, a new optofluidic system for cell line development

Berkeley Lights, Inc., a life sciences tools company, today announced the launch of the Beacon Select™, the company's new optofluidic system for cell line development (CLD).

From Bruker Cellular Analysis 19 Jan 2023

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

In this interview, News Medical spoke to Kate Lawrenson, Ph.D., about their latest research which detailed the molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

19 Jan 2023

Study elucidates the potential role of STRO-001 in B-cell non-Hodgkin lymphoma

A new research paper was published in Oncotarget's Volume 14 on January 12, 2023, entitled, "Targeting CD74 in B-cell non-Hodgkin lymphoma with the antibody-drug conjugate STRO-001."

18 Jan 2023

Research provides a comprehensive structural framework to design safer pain-relieving drugs

In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring peptides.

18 Jan 2023

Study finds wide variation in the quality of care for lung cancer across the U.S.

Treatment for lung cancer is rapidly evolving, with new technologies and research-proven procedures.

18 Jan 2023

Research explores the utility of epigenetically predicted BMI

DNA methylation is an accurate predictor of current BMI and a poor predictor of future BMI.

18 Jan 2023

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Researchers performed an observational study among COVID-19 patients and their close contacts registered with the Bangkok home health care services in Thailand.

18 Jan 2023

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Researchers performed immunoglobulin (Ig)M and IgG epitope mapping against 487 SARS-CoV-2 peptides.

18 Jan 2023

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 15, Issue 1, entitled, "Single-cell transcriptomics of peripheral blood in the aging mouse."

18 Jan 2023

Study sheds new light on how the B cell academy mounts a diverse immune response

Cells jostling for a spot in a germinal center face a cutthroat admissions process. Formed after exposure to a pathogen or vaccine, germinal centers act as a kind of immune system training academy, helping B cells refine their response to the threat.

18 Jan 2023

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

Researchers explored ways galectins can impact immunity and discussed the opportunities and challenges in the field.

18 Jan 2023

What factors are associated with successful dietary weight loss interventions?

A new study explored the factors governing the success of long- and short-term weight loss interventions.

18 Jan 2023

Researchers explore the mechanism involved in the living world’s fastest cell movements

Raphidocystis contractilis belongs to Heliozoa, a group of eukaryotes commonly found in fresh, brackish, and sea water.

18 Jan 2023

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two major hallmarks of quality

The Stem Cell and Bone Marrow Transplant Program at Cedars-Sinai Cancer was recently recognized with two important hallmarks of quality: official accreditation for CAR T-cell therapy, and a third year in a row ranking among the top adult bone marrow transplant programs in the U.S.

18 Jan 2023

Upregulation of Robo4 expression reduces mortality from severe infection

The researchers screened a library of drugs using a mouse endothelial cell line to identify pathways that are involved in the regulation of Robo4 and found that two competitive SMAD signaling pathways appear to regulate Robo4 expression.

18 Jan 2023

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Mice exposed to World Trade Center dust exhibit a significant impairment in spatial recognition and short- and long-term memory, as well as changes in genes related to immune-inflammatory responses and blood-brain barrier disruption, according to a study conducted by researchers from the Icahn School of Medicine at Mount Sinai and published January 17 in the Journal of Alzheimer's Disease.

17 Jan 2023

B Cell News and Research

Understanding the mechanisms involved in heart disease and cancers

How is long COVID diagnosed in adults?

Study shows SARS-CoV-2 exhibits differential tropism for nasal epithelial cells with age

How do mutations in emergent SARS-CoV-2 Omicron variants affect viral function, human immunity, and recognition by therapeutic antibodies?

Berkeley Lights launches Beacon Select™, a new optofluidic system for cell line development

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

Study elucidates the potential role of STRO-001 in B-cell non-Hodgkin lymphoma

Research provides a comprehensive structural framework to design safer pain-relieving drugs

Study finds wide variation in the quality of care for lung cancer across the U.S.

Research explores the utility of epigenetically predicted BMI

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Epitope mapping reveals the humoral responses against the main SARS-CoV-2 structural proteins in infected patients from Africa

Researchers use single-cell RNA-sequencing to study the aging peripheral blood in mice

Study sheds new light on how the B cell academy mounts a diverse immune response

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

What factors are associated with successful dietary weight loss interventions?

Researchers explore the mechanism involved in the living world’s fastest cell movements

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two major hallmarks of quality

Upregulation of Robo4 expression reduces mortality from severe infection

Exposure to World Trade Center particulate matter accelerates cognitive deterioration in mice model of Alzheimer's

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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