Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

A new bioRxiv* preprint reports on the successful use of a protocol to expand SARS-CoV-2-reactive T-cells a thousand-fold.

2 Jun 2021

New study sheds light on why many COVID-19 patients suffer from hypoxia

A new study published in the journal Stem Cell Reports by University of Alberta researchers is shedding light on why many COVID-19 patients, even those not in hospital, are suffering from hypoxia--a potentially dangerous condition in which there is decreased oxygenation in the body's tissues.

2 Jun 2021

Miniature 3D bone marrow model could lead to personalized treatment for blood platelet disorders

A new miniature 3D model of human bone marrow has been described today in the open-access eLife journal.

1 Jun 2021

Study could help identify risk of secondary leukaemia in certain children

Scientists from the Wellcome Sanger Institute and the University of Cambridge found that in children with neuroblastoma - a cancer of immature nerve cells - treatment with platinum chemotherapy caused changes to the genome that could then cause leukaemia in some children later on.

31 May 2021

New study may help improve stem cell transplantation, lead to better drugs

Your immune system is always busy fighting incoming threats. It consists of a system of cells, and when there is a shortage of cells, it affects the performance of the immune system.

29 May 2021

Study may lead to new treatments that eliminate cancer cells without harming other body cells

Normal cells usually have multiple solutions for fixing problems. For example, when DNA becomes damaged, healthy white blood cells can use several different strategies to make repairs.

28 May 2021

Next-generation SARS-CoV-2 subunit vaccine candidate elicits powerful immunity in preclinical trials

New research – by scientists at the University of Chicago, Johns Hopkins School of Medicine and the University of Iowa in the USA – describes a novel COVID-19 vaccine candidate that has achieved impressive immunologic results in mouse studies.

25 May 2021

Little evidence for mRNA COVID-19 vaccine-associated thrombocytopenia, suggests new FDA study

Even as a host of vaccines have been rolled out to counter the coronavirus disease 2019 (COVID-19) pandemic, some serious adverse effects have been reported, in the form of thrombocytopenia. A new study in the journal Vaccine reports the results of an evaluation of reported cases of this condition, using data from the Vaccine Adverse Event Reporting System (VAERS).

24 May 2021

Mild cases of COVID-19 provide lasting antibody protection, shows study

Months after recovering from mild cases of COVID-19, people still have immune cells in their body pumping out antibodies against the virus that causes COVID-19, according to a study from researchers at Washington University School of Medicine in St. Louis. Such cells could persist for a lifetime, churning out antibodies all the while.

24 May 2021

Researchers investigate link between the liver’s immune system composition and NASH pathology

Our livers work hard to perform an entire range of activities: helping us digest food, maintaining body temperature and serving as an important checkpoint of the immune system for everything that we eat.

24 May 2021

Blocking TGFβ1 could improve hematopoiesis in AML patients, indicates study

Bone marrow failure due to acute myeloid leukemia (AML) is a significant factor behind the disease's high rate of morbidity and mortality. Previous studies in mice suggest that AML cells inhibit healthy hematopoietic (blood) stem and progenitor cells (HSPC).

20 May 2021

Extensive cancer research data to be presented at the 2021 ASCO Annual Meeting

Rutgers Cancer Institute of New Jersey, a leader in cutting-edge clinical trials and health outcomes analyses and a designated Comprehensive Cancer Center by the National Cancer Institute, together with RWJBarnabas Health, today announced that data from its cancer clinical research program will be presented at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting, to be held virtually from June 4-8.

20 May 2021

People with venom allergies are more likely to have bone marrow disorder

Researchers at Michigan Medicine found that people with venom allergies are much more likely to suffer mastocytosis, a bone marrow disorder that causes higher risk of fatal reactions.

19 May 2021

Robust T cell and humoral immune response to SARS-CoV-2 in patients with immunodeficiency

A study of immune-deficient adults and children has shown that patients who fail to respond positively to infections and vaccinations have robust humoral immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) structural proteins.

18 May 2021

Scientists develop experimental direct-acting antiviral therapy to treat COVID-19

An international team of scientists from the Menzies Health Institute Queensland (MHIQ) at Griffith University and from City of Hope, a research and treatment center for cancer, diabetes and other life-threatening diseases in the U.S., have developed an experimental direct-acting antiviral therapy to treat COVID-19.

18 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Sepsis can cause alterations in the functioning of defense cells that lead to death

An article published in Frontiers in Immunology suggests that sepsis can cause alterations in the functioning of defense cells that persist even after the patient is discharged from hospital.

12 May 2021

Investigational gene therapy can restore immune function in children with inherited immunodeficiency disorder

An investigational gene therapy can safely restore the immune systems of infants and children who have a rare, life-threatening inherited immunodeficiency disorder, according to research supported in part by the National Institutes of Health.

12 May 2021

Researchers conduct first-in-man clinical trial for new stem cell technology

Institutes and centres under the SingHealth Duke-NUS Academic Medical Centre (AMC) are joining hands together with Singapore's first private cord blood bank, Cordlife Group Limited (Cordlife), to test a novel technology that expands the number of blood-forming stem cells from stored umbilical cord blood (UCB) in a first-in-man study in Singapore.

12 May 2021

An intranasal COVID-19 vaccine elicits long-lasting immunity against SARS-CoV-2 variants in vivo

A team of scientists from the Washington University School of Medicine and the University of Texas Medical Branch, USA, has recently evaluated the durability and robustness of an adenovirus-vectored, spike-based intranasal COVID-19 vaccine in mice.

11 May 2021

Bone Marrow News and Research

Further Reading

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

New study sheds light on why many COVID-19 patients suffer from hypoxia

Miniature 3D bone marrow model could lead to personalized treatment for blood platelet disorders

Study could help identify risk of secondary leukaemia in certain children

New study may help improve stem cell transplantation, lead to better drugs

Study may lead to new treatments that eliminate cancer cells without harming other body cells

Next-generation SARS-CoV-2 subunit vaccine candidate elicits powerful immunity in preclinical trials

Little evidence for mRNA COVID-19 vaccine-associated thrombocytopenia, suggests new FDA study

Mild cases of COVID-19 provide lasting antibody protection, shows study

Researchers investigate link between the liver’s immune system composition and NASH pathology

Blocking TGFβ1 could improve hematopoiesis in AML patients, indicates study

Extensive cancer research data to be presented at the 2021 ASCO Annual Meeting

People with venom allergies are more likely to have bone marrow disorder

Robust T cell and humoral immune response to SARS-CoV-2 in patients with immunodeficiency

Scientists develop experimental direct-acting antiviral therapy to treat COVID-19

Sepsis can cause alterations in the functioning of defense cells that lead to death

Sepsis can cause alterations in the functioning of defense cells that lead to death

Investigational gene therapy can restore immune function in children with inherited immunodeficiency disorder

Researchers conduct first-in-man clinical trial for new stem cell technology

An intranasal COVID-19 vaccine elicits long-lasting immunity against SARS-CoV-2 variants in vivo

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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