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Monoclonal antibody shows promise in slowing progression of ALS

New research reveals a type of monoclonal antibody already tested in certain forms of cancer may be a promising treatment in stopping the progression of amyotrophic lateral sclerosis, or ALS, a fatal neurodegenerative disease.

31 Jul 2023

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

A novel vaccine that targets inflamed brain cells associated with Alzheimer's disease may hold the key to potentially preventing or modifying the course of the disease, according to preliminary research presented at the American Heart Association's Basic Cardiovascular Sciences Scientific Sessions 2023.

31 Jul 2023

Researchers discover new spiroindolin-1,2-diazepine derivatives with anti-Alzheimer therapeutic potential

In a recent study, researchers designed substituted spiro indolin-1,2-diazepine derivatives '5a–v' with cholinesterase inhibitory activities as anti-Alzheimer's disease agents.

31 Jul 2023

Golgi apparatus may play a role in neuronal circuit reorganization during postnatal brain development

Neurons are the cells that constitute neural circuits and use chemicals and electricity to receive and send messages that allow the body to do everything, including thinking, sensing, moving, and more.

28 Jul 2023

Periaqueductal gray is essential for play and laughter in rats

To study play behaviors in animals, scientists must be able to authentically simulate play-conducive environments in the laboratory.

28 Jul 2023

Study analyzes the similarities between near-death experiences and psychedelic experiences

Researchers analyzed the similarities and differences between a near-death experience (NDE) while in a coma and the experience induced by a psychedelic drug.

28 Jul 2023

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

Researchers pursued insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of MS.

21 Jul 2023

New ultra-flexible neural implant records single-neuron activity in deep-brain regions

A new ultra-small and ultra-flexible electronic neural implant, delivered via blood vessels, can record single-neuron activity deep within the brains of rats, according to new study.

20 Jul 2023

Immune cells may play role in regulating maternal behavior

Immune system changes in the pregnant body that protect the fetus appear to extend to the brain, where a decrease in immune cells late in gestation may factor into the onset of maternal behavior, new research in rats suggests.

19 Jul 2023

Neuroscientists discover new brain cells that help correct navigational errors

During routine navigation in daily life, our brains use spatial mapping and memory to guide us from point A to point B. Just as routine: making a mistake in navigation that requires a course correction.

19 Jul 2023

The brain structure of superagers: identifying demographic, lifestyle, and clinical factors associated with their phenotype

Researchers used machine learning models to assess the physical and primarily mental performance of superagers.

19 Jul 2023

Study provides clues to the neural basis of consciousness

More than a quarter of all stroke victims develop a bizarre disorder - they lose conscious awareness of half of all that their eyes perceive.

18 Jul 2023

Targeted brain stimulation shows promise for treating TBI-related memory loss

Traumatic brain injury (TBI) has disabled 1 to 2% of the population, and one of their most common disabilities is problems with short-term memory. Electrical stimulation has emerged as a viable tool to improve brain function in people with other neurological disorders.

18 Jul 2023

Magnetic susceptibility as a promising marker for predicting future severity of Parkinson's disease

Researchers evaluate quantitative magnetic susceptibility mapping in detecting quantifiable markers of Parkinson’s disease progression.

18 Jul 2023

Primate brain cell atlas provides molecular and cellular basis for neural circuit research

A team of nearly 100 scientists recently mapped the cell-type taxonomy in the macaque cortex and revealed the relationship between cell-type composition and various primate brain regions by using the self-developed spatial transcriptome sequencing technology Stereo-seq and snRNA-seq technology, which provides a molecular and cellular basis for further investigation into neural circuits.

14 Jul 2023

Cortex News and Research

Monoclonal antibody shows promise in slowing progression of ALS

Novel vaccine targets inflamed brain cells in Alzheimer's to modify the course of disease

Researchers discover new spiroindolin-1,2-diazepine derivatives with anti-Alzheimer therapeutic potential

Golgi apparatus may play a role in neuronal circuit reorganization during postnatal brain development

Periaqueductal gray is essential for play and laughter in rats

Study analyzes the similarities between near-death experiences and psychedelic experiences

Insights into the pathophysiological mechanisms governing neuropsychiatric symptoms of multiple sclerosis

New ultra-flexible neural implant records single-neuron activity in deep-brain regions

Immune cells may play role in regulating maternal behavior

Neuroscientists discover new brain cells that help correct navigational errors

The brain structure of superagers: identifying demographic, lifestyle, and clinical factors associated with their phenotype

Study provides clues to the neural basis of consciousness

Targeted brain stimulation shows promise for treating TBI-related memory loss

Magnetic susceptibility as a promising marker for predicting future severity of Parkinson's disease

Primate brain cell atlas provides molecular and cellular basis for neural circuit research

Quality sleep can help bolster resilience to mental health disorders

CBD exposure during pregnancy can potentially harm a developing fetus

Study identifies a signature of risk for developing hypomania

Brain's electric fields drive neural activity to form memories

Abnormal cortical folding linked to major depressive disorder

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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