Malignant News and Research

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New potential target for treating metastasized oral malignant melanoma in dogs

Scientists have shown that the biological molecule PD-L1 is a potential target for the treatment of metastasized oral malignant melanoma in dogs.

23 Apr 2021

FDA approves clinical trials to test the safety of cancer-detection technology

The U.S. Food and Drug Administration has approved human clinical trials to test the safety of cancer-detection technology developed at Case Western Reserve University: a tumor-targeting contrast agent that accurately detects aggressive prostate cancer in a magnetic resonance imaging (MRI) scan.

22 Apr 2021

Researchers develop a new method for the detection and evolution of kidney cancer

The research groups Mintota and Photochemistry Reactivity Group of the faculties of Chemistry and Pharmacy of the University of Valencia have developed a method for the detection and evolution of kidney cancer through urine and the dispersion of gold nanoparticles, in what is the first system that will provide reliable information on the existence and progress of this pathology.

21 Apr 2021

POT1 gene linked to glioma development mediates its effects in a sex-specific manner

Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner.

20 Apr 2021

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

In a study by Yale Cancer Center, researchers report on the discovery of a common mechanism that promotes both autoimmune diseases and blood cancers, including the blood diseases Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL) and Mantle Cell Lymphoma (MCL).

19 Apr 2021

Researchers develop an effective strategy to fight against chronic myelomonocytic leukemia

Leukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at Tokyo Medical and Dental University describe an ingenious strategy against chronic myelomonocytic leukemia (CMML) wherein an antibody-drug conjugate (ADC) comprising a cytotoxic drug payload linked to an antibody that selectively targets specific cell lines effectively blocks malignant cell proliferation at source.

16 Apr 2021

An ion pump tested as a possible method to treat malignant brain tumors

Despite surgery and subsequent treatment with chemotherapy and radiation, the majority of patients experience recurrence of malignant brain tumors.

15 Apr 2021

Research may lead to a significant breakthrough in the battle against deadly brain tumors

Groundbreaking research from Tel Aviv University may lead to a significant breakthrough in the battle against deadly brain cancer.

12 Apr 2021

Deep learning algorithms improve diagnostic performance of breast ultrasound

Ultrasound is widely used to detect breast cancer early, but misdiagnosis of benign lesions as malignant tumors sometimes leads to unnecessary biopsies.

5 Apr 2021

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

Cancer is the world's second deadliest disease which contributes towards the fatality of over 10 million people per year.

3 Apr 2021

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

A UCLA research team has shown that using a truncated form of the CD4 molecule as part of a gene therapy to combat HIV yielded superior and longer-lasting results in mouse models than previous similar therapies using the CD4 molecule.

3 Apr 2021

Cancer patients treated with immunotherapy at high risk of developing thrombotic complications

In a study recently published in the leading journal "Blood", Florian Moik and Cihan Ay from the Division of Hematology and Hemastasology of the Department of Medicine I of MedUni Vienna/Vienna General Hospital, working in collaboration with the Division of Oncology, the Department of Dermatology and the dispensary of Vienna General Hospital, provided preliminary data on the incidence, risk factors and clinical outcomes of thrombotic complications in this new form of cancer treatment.

31 Mar 2021

New blood test makes it easier to follow the progression of multiple myeloma

A new method makes it much easier to follow the progression of multiple myeloma, a form of blood cancer.

26 Mar 2021

New imaging technique can better identify the presence of residual cancers in rectal tissues

Rectal cancer, along with colon cancer, is the third-most common type of cancer in the United States, and treatment and surgery greatly affect the quality of life of patients.

26 Mar 2021

FDA authorizes marketing of new device for short-term treatment of gait deficit in MS patients

Today, the U.S. Food and Drug Administration authorized marketing of a new device indicated for use as a short-term treatment of gait deficit due to mild to moderate symptoms from multiple sclerosis (MS).

26 Mar 2021

Study uncovers new biomarkers in patients with malignant melanoma

A team of researchers has studied the molecular profile of small “messenger” vesicles called exosomes, produced by cancer stem cells (CSCs), which play a key role in the process of carcinogenesis and metastasis in the blood of patients with malignant melanoma.

25 Mar 2021

Novel gene therapy reprograms glioma cells into functional neurons

Glioma is a fatal neurological disorder that has limited interventional treatment, despite extensive research over the past several decades.

24 Mar 2021

Checkpoint inhibition could offer an effective treatment option for patients with rare cancer

Peritoneal mesothelioma is cancer that develops in the lining of the abdomen, which is known as the peritoneum.

24 Mar 2021

An electronic nose to detect harmful atmospheric free radicals

An international project involving researchers at Helmholtz-Zentrum Dresden-Rossendorf (HZDR) is receiving 3.2 million euros from the European research and innovation program "Horizon 2020" to develop a cost-effective method for measuring certain air pollutants.

23 Mar 2021

Cellular senescence of cancer-associated fibroblasts play a key role in peritoneal dissemination

Through an analysis of cellular components (cell fractions) from malignant ascites (fluid buildup in the abdomen caused by gastric cancer), a research collaboration based in Kumamoto University (Japan) has demonstrated that cellular senescence of cancer-associated fibroblasts (CAFs) play an important role in the peritoneal dissemination of gastric cancer foci (cells different from surrounding cells).

23 Mar 2021

Malignant News and Research

New potential target for treating metastasized oral malignant melanoma in dogs

FDA approves clinical trials to test the safety of cancer-detection technology

Researchers develop a new method for the detection and evolution of kidney cancer

POT1 gene linked to glioma development mediates its effects in a sex-specific manner

Yale scientists uncover common mechanism that promotes autoimmune diseases and blood cancers

Researchers develop an effective strategy to fight against chronic myelomonocytic leukemia

An ion pump tested as a possible method to treat malignant brain tumors

Research may lead to a significant breakthrough in the battle against deadly brain tumors

Deep learning algorithms improve diagnostic performance of breast ultrasound

Study paves way for effective monitoring of chemotherapeutic drug level in cancer patients

New approach to CAR T gene therapy yields efficient and longer-lasting response against HIV

Cancer patients treated with immunotherapy at high risk of developing thrombotic complications

New blood test makes it easier to follow the progression of multiple myeloma

New imaging technique can better identify the presence of residual cancers in rectal tissues

FDA authorizes marketing of new device for short-term treatment of gait deficit in MS patients

Study uncovers new biomarkers in patients with malignant melanoma

Novel gene therapy reprograms glioma cells into functional neurons

Checkpoint inhibition could offer an effective treatment option for patients with rare cancer

An electronic nose to detect harmful atmospheric free radicals

Cellular senescence of cancer-associated fibroblasts play a key role in peritoneal dissemination

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