Platelet News and Research

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Regeneron Pharmaceuticals expands ophthalmology portfolio

Regeneron Pharmaceuticals, Inc. today announced that it has expanded its ophthalmology portfolio by acquiring full exclusive rights to two families of novel antibodies invented at Regeneron and previously included in Regeneron's antibody collaboration with Sanofi.

3 May 2013

SSRIs associated with increased risk of bleeding, transfusion, readmission and death

Selective serotonin reuptake inhibitors (SSRIs) - among the most widely prescribed antidepressant medications - are associated with increased risk of bleeding, transfusion, hospital readmission and death when taken around the time of surgery, according to an analysis led by researchers at UC San Francisco and Baystate Medical Center in Springfield, Mass.

30 Apr 2013

Bioactive plasma-based biomaterials can accelerate tissue healing

Platelet-rich plasma derived from blood contains growth factors and other bioactive molecules that promote healing at sites of tissue injury. However, it is difficult to deliver and retain these molecules at a target site, and clinical results have proven to be mixed - until now.

16 Apr 2013

Researchers explore how blocking EGFR changes signaling in glioblastoma cells

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor, fuels a wide variety of cancers-including a highly malignant brain cancer known as glioblastoma.

9 Apr 2013

Certain brain tumors develop drug resistance by exploiting normal cellular signaling pathways

Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors.

9 Apr 2013

Study: Pradaxa drug may increase risk and severity of viral infections

A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral infections, including flu and myocarditis, a viral infection of the heart and a significant cause of sudden death in children and young adults.

2 Apr 2013

Research on sports-related concussion, sudden cardiac death to be presented at 2013 AMSSM Annual Meeting

The latest research for sports-related concussion and sudden cardiac death in athletes, in addition to a record number of sports medicine research submissions, will be presented by members of the American Medical Society for Sports Medicine at the 2013 AMSSM Annual Meeting.

2 Apr 2013

PRP treatment reduces pain in patients with chronic tennis elbow

Eighty-four percent of patients suffering from chronic tennis elbow (lateral epicondylar tendinopathy) reported significantly less pain and elbow tenderness at six months following platelet rich plasma (PRP) treatment, according to results from the largest, multi-center study, to date, on PRP and tennis elbow, presented today at the 2013 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).

24 Mar 2013

Large population of healthy people take Aspirin to prevent cardiovascular disease: Study

A new study out of the Faculty of Medicine & Dentistry shows a large population of healthy people are taking Aspirin to prevent cardiovascular disease, despite the fact that new literature shows it isn't as beneficial as once thought.

20 Mar 2013

Cangrelor solidly outperforms clopidogrel during percutaneous coronary intervention

The experimental anti-clotting drug cangrelor solidly outperformed commonly used clopidogrel in a large global trial of patients who underwent coronary stent procedures, according to data from the phase III CHAMPION PHOENIX study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

Cangrelor more effective than clopidogrel in preventing blood clots

A new and experimental anti-clotting drug, cangrelor, proved better than the commonly used clopidogrel and was significantly more effective at preventing blood clots in a large trial of patients who underwent coronary stent procedures.

12 Mar 2013

Failure to use aspirin before angioplasty increases death rate

Despite recommendations from leading medical groups, a surprising number of patients are not given aspirin before artery-clearing coronary angioplasty and stenting, and those patients have a significantly higher in-hospital death rate, according to research from a Michigan network being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Novel drug seems to increase effectiveness of usual chemotherapy against IBC

Researchers in the University of Delaware's Department of Biological Sciences are investigating a new drug that has shown positive results in early tests of its ability to fight a rare and aggressive form of breast cancer.

8 Mar 2013

Study investigates how cancer cells 'hijack' platelets

A new research study has investigated how cancer cells 'hijack' blood cells known as platelets, enabling cancer to spread around the body and promoting the growth of new tumours, it was reported today at the annual Royal College of Surgeons in Ireland (RCSI) Research Day.

7 Mar 2013

Study shows how high shear stress could cause VWF to change shape and form blood clots

New research from Rice University, Baylor College of Medicine (BCM) and the Puget Sound Blood Center (PSBC) has revealed how stresses of flow in the small blood vessels of the heart and brain could cause a common protein to change shape and form dangerous blood clots.

6 Mar 2013

Wright Medical Group acquires BioMimetic Therapeutics

Wright Medical Group, Inc. today announced that it has completed its acquisition of BioMimetic Therapeutics, Inc. The transaction combines BioMimetic's breakthrough biologics platform and pipeline with Wright's established sales force and product portfolio, to further accelerate growth opportunities in Wright's Extremities business.

1 Mar 2013

Platelet News and Research

Regeneron Pharmaceuticals expands ophthalmology portfolio

SSRIs associated with increased risk of bleeding, transfusion, readmission and death

Bioactive plasma-based biomaterials can accelerate tissue healing

Researchers explore how blocking EGFR changes signaling in glioblastoma cells

Certain brain tumors develop drug resistance by exploiting normal cellular signaling pathways

Study: Pradaxa drug may increase risk and severity of viral infections

Research on sports-related concussion, sudden cardiac death to be presented at 2013 AMSSM Annual Meeting

PRP treatment reduces pain in patients with chronic tennis elbow

Large population of healthy people take Aspirin to prevent cardiovascular disease: Study

Cangrelor solidly outperforms clopidogrel during percutaneous coronary intervention

Cangrelor more effective than clopidogrel in preventing blood clots

Failure to use aspirin before angioplasty increases death rate

Novel drug seems to increase effectiveness of usual chemotherapy against IBC

Study investigates how cancer cells 'hijack' platelets

Study shows how high shear stress could cause VWF to change shape and form blood clots

Wright Medical Group acquires BioMimetic Therapeutics

Protamine–heparin complex antibodies raise concerns

FDA approves new vial size for CSL Behring’s Privigen to treat primary immunodeficiency

Study assesses ischaemic and haemorrhagic risk linked with history of stroke or TIA

Risk factors for invasive candidiasis in infants clarified

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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