Receptor News and Research

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Experimental compound reduces cell death, inflammation, and organ damage in diabetes

An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes.

29 Oct 2025

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Peripheral afferent neurons - nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord) - are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often accompanied by severe pain.

29 Oct 2025

Novel computational platform can design synthetic protein receptors from scratch

Cancer immunotherapy, especially using T cells, is showing a lot of promise in treating blood cancers. Bioengineered T cells, especially those equipped with chimeric antigen receptors (CAR-T cells), have revolutionized cancer treatment.

28 Oct 2025

New drug can have a promising effect in cancer patients with active brain metastases

An international clinical study led by the Medical University of Vienna shows that the drug patritumab deruxtecan (HER3-DXd) can have a promising effect in patients with active brain metastases of various tumor types.

28 Oct 2025

Air pollution, even below EPA guidelines, increases breast cancer risk

Women living in parts of the United States with lower air quality, especially neighborhoods with heavy emissions from motor vehicles, are more likely to develop breast cancer, according to a multiyear analysis involving more than 400,000 women and 28,000 breast cancer cases.

28 Oct 2025

New study reveals how the glucocorticoid receptor forms complex structures inside cells

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

27 Oct 2025

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

New research from the Champalimaud Foundation (CF) reveals how missing just one essential amino acid can change gene expression and the brain's sensory systems, prompting animals to seek out protein-rich yeast and gut bacteria that help them restore nutritional balance and survive in times of need.

27 Oct 2025

Study reveals how eosinophils play a protective role against Candida infections

New research shows that eosinophils, immune cells usually linked to allergies, also play a protective role against Candida infections by using the CD48 receptor to recognize the fungus and release proteins that stop its growth.

27 Oct 2025

Semaglutide protects the heart beyond weight loss, SELECT trial shows

Semaglutide lowered the risk of major adverse cardiovascular events across all body weight and waist circumference levels in people with overweight or obesity and cardiovascular disease. Early waist reduction explained only a third of this benefit, showing that semaglutide’s heart protection extends beyond fat loss.

26 Oct 2025

Breakthrough menopause drug for hot flashes and night sweats gains FDA approval

The federal Food and Drug Administration today approved a new menopause drug that reduces hot flashes and night sweats after the drug was successfully tested at UVA Health and other sites in the United States and around the world.

24 Oct 2025

Unlocking the secrets of vascular health through eye imaging

The tiny blood vessels in your eyes might hold the key to predicting a person's risk of developing heart disease and how fast they're biologically aging, according to researchers at McMaster University and Population Health Research Institute (PHRI) - a joint institute of Hamilton Health Sciences and McMaster.

24 Oct 2025

Researchers reveal how maternal stress reshapes fetal growth and brain development

Maternal stress, encompassing physical, emotional, and psychological distress, remains a widespread yet underestimated risk during pregnancy.

24 Oct 2025

Leveraging the power of T cells for more effective and durable cancer immunotherapies

T cells play central roles in the adaptive immune response against cancer. Their functional inactivation is a primary driver of tumor progression, making the reactivation of T cell function a main goal in immunotherapy.

24 Oct 2025

Researchers identify nervous system components driving gastrointestinal cancer growth

Australian researchers have identified two nervous system components that drive tumor growth in gastrointestinal cancers, creating promising new avenues for treatment with existing approved therapies.

24 Oct 2025

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

A collaborative research group led by Haruna Kimura (graduate student), Dr. Akito Hasegawa (Assistant Professor), and Prof. Riichiro Abe from the Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, together with Prof. Takemasa Ozawa from the Department of Chemistry, School of Science, The University of Tokyo, and Dr. Yoichi Ogawa (Lecturer) from the Department of Dermatology, Faculty of Medicine, University of Yamanashi, has developed a novel therapeutic candidate that may improve the prognosis of severe cutaneous adverse reactions such as Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN).

24 Oct 2025

How COVID mRNA vaccines may make cancer treatments more effective

Researchers found that COVID-19 mRNA vaccines, when given within 100 days of starting immune checkpoint inhibitors, were linked to significantly longer survival in lung and melanoma cancer patients. The vaccines trigger a powerful type-I interferon response that primes tumors to become more responsive to immunotherapy.

23 Oct 2025

New discovery reshapes understanding of how brain inflammation arises in Alzheimer's disease

Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes scientists' understanding of how brain inflammation arises in Alzheimer's disease.

23 Oct 2025

Research opens new avenues for treating asthma and other inflammatory diseases

For decades, scientists have thought they understood the biochemical machinery that causes asthma-inflammation in the lungs that constricts airways and makes it hard to breathe.

23 Oct 2025

Biodesix announces expanded Bio-Rad Laboratories partnership agreement to develop Droplet Digital™ PCR high complexity assays

Biodesix, Inc., a leading diagnostics solutions company, today announced the signing of an expanded partnership agreement under which Biodesix will conduct the development, clinical validation, and regulatory submissions of in vitro diagnostic (IVD) assays to enable highly sensitive detection of multiple genomic markers focused on oncology applications, utilizing Bio-Rad's Droplet Digital™ PCR (ddPCR™) technology on Bio-Rad's QX600 platform.

23 Oct 2025

How psychedelics profoundly reshape the perception of time and consciousness

A perspective article published in Psychedelics by Prof. Xiaohui Wang and colleagues examines how psychedelic substances profoundly reshape the perception of time, offering unprecedented insights into consciousness and potential therapeutic applications.

23 Oct 2025

Receptor News and Research

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

Two analgesic drugs may one day be repurposed as anti-tumor therapies

Novel computational platform can design synthetic protein receptors from scratch

New drug can have a promising effect in cancer patients with active brain metastases

Air pollution, even below EPA guidelines, increases breast cancer risk

New study reveals how the glucocorticoid receptor forms complex structures inside cells

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

Study reveals how eosinophils play a protective role against Candida infections

Semaglutide protects the heart beyond weight loss, SELECT trial shows

Breakthrough menopause drug for hot flashes and night sweats gains FDA approval

Unlocking the secrets of vascular health through eye imaging

Researchers reveal how maternal stress reshapes fetal growth and brain development

Leveraging the power of T cells for more effective and durable cancer immunotherapies

Researchers identify nervous system components driving gastrointestinal cancer growth

Researchers uncover and inhibit a key cell death pathway in severe cutaneous adverse reactions

How COVID mRNA vaccines may make cancer treatments more effective

New discovery reshapes understanding of how brain inflammation arises in Alzheimer's disease

Research opens new avenues for treating asthma and other inflammatory diseases

Biodesix announces expanded Bio-Rad Laboratories partnership agreement to develop Droplet Digital™ PCR high complexity assays

How psychedelics profoundly reshape the perception of time and consciousness

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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